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Gallotannin
A gallotannin is any of a class of molecules belonging to the hydrolysable tannins. Gallotannins are polymers formed when gallic acid, a polyphenol monomer, esterifies and binds with the hydroxyl group of a polyol carbohydrate such as glucose. Metabolism Gallate 1-beta-glucosyltransferase uses UDP-glucose and gallate to produce UDP and 1-galloyl-β-D-glucose. Beta-glucogallin O-galloyltransferase uses 1-O-galloyl-β-D-glucose to produce D-glucose and 1-O,6-O-digalloyl-β-D-glucose. Beta-glucogallin-tetrakisgalloylglucose O-galloyltransferase uses 1-O-galloyl-β-D-glucose and 1,2,3,6-tetrakis-O-galloyl-β-D-glucose to produce D-glucose and 1,2,3,4,6-pentakis-O-galloyl-β-D-glucose (1,2,3,4,6-penta-O-galloyl-β-D-glucose, the common precursor of gallotannins and the related ellagitannins). Tannase is a key enzyme in the degradation of gallotannins that uses digallic acid and H2O to produce gallic acid. See also * List of antioxidants in food This is a list of antio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tannase
The enzyme tannase (EC 3.1.1.20) catalyzes the following reaction: : digallate + H2O = 2 gallate It is a key enzyme in the degradation of gallotannins and ellagicitannins, two types of hydrolysable tannins. Specifically, tannase catalyzes the hydrolysis of ester and depside bonds of hydrolysable tannins to release glucose and gallic or ellagic acid. Tannase belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name is tannin acylhydrolase. Other names in common use include tannase S, and tannin acetylhydrolase. This enzyme has two known domains and one known active site. Tannase can be found in plants, bacteria, and fungi and has different purposes depending on the organism it is found in. Tannase also has many purposes for human use. The production of gallic acid is important in the pharmaceutical industry as it's needed to create trimethoprim, an antibacterial drug. Tannase also has many applications in the food and bevera ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hydrolysable Tannin
A hydrolysable tannin or pyrogallol-type tannin is a type of tannin that, on heating with hydrochloric or sulfuric acids, yields gallic or ellagic acids. At the center of a hydrolysable tannin molecule, there is a carbohydrate (usually D-glucose but also cyclitols like quinic or shikimic acids). The hydroxyl groups of the carbohydrate are partially or totally esterified with phenolic groups such as gallic acid in gallotannins or ellagic acid in ellagitannins. Hydrolysable tannins are mixtures of polygalloyl glucoses and/or poly-galloyl quinic acid derivatives containing in between 3 up to 12 gallic acid residues per molecule. Hydrolysable tannins are hydrolysed by weak acids or weak bases to produce carbohydrate and phenolic acids. Examples of gallotannins are the gallic acid esters of glucose in tannic acid (C76H52O46), found in the leaves and bark of many plant species. Hydrolysable tannins can be extracted from different vegetable plants, such as chestnut wood (''Cast ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1-galloyl-β-D-glucose
Glucogallin is chemical compound formed from gallic acid and β-D-glucose. It can be found in oaks species like the North American white oak (''Quercus alba''), European red oak (''Quercus robur'') and Amla fruit (''Phyllanthus emblica''). It is formed by a gallate 1-beta-glucosyltransferase (UDP-glucose: gallate glucosyltransferase), an enzyme performing the esterification of two substrates, UDP-glucose and gallate to yield two products, UDP and glucogallin. This enzyme can be found in oak leaf preparations. This the first step in the biosynthesis of gallotannins. The molecule is then used by enzymes in the gallotannins synthetics pathway like beta-glucogallin O-galloyltransferase or beta-glucogallin-tetrakisgalloylglucose O-galloyltransferase. β-Glucogallin is aldose reductase inhibitor Aldose reductase inhibitors are a class of drugs being studied as a way to prevent eye and nerve damage in people with diabetes. Mechanism Their target, aldose reductase, is an enzyme t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1,2,3,4,6-pentagalloyl-glucose
Pentagalloylglucose, or more specifically 1,2,3,4,6-penta-''O''-galloyl-β-D-glucose, is the pentagallic acid ester of glucose. It is a gallotannin and the precursor of ellagitannins. Pentagalloylglucose can precipitate proteins, including human salivary α-amylase. Natural occurrence Pentagalloylglucose can be found in ''Punica granatum'' (pomegranate), '' Elaeocarpus sylvestris'', ''Rhus typhina'' (Staghorn sumac), ''Paeonia suffruticosa'' (Tree Peony),., ''Mangifera indica'' (mango) and '' Bouea macrophylla'' Griffith ( maprang). Biosynthesis The enzyme beta-glucogallin-tetrakisgalloylglucose O-galloyltransferase uses 1-O-galloyl-β-D-glucose and 1,2,3,6-tetrakis-O-galloyl-β-D-glucose to produce D-glucose and pentagalloylglucose. Metabolism Tellimagrandin II is formed from pentagalloylglucose by oxidative dehydrogenation and coupling of 2 galloyl groups. β-glucogallin: 1,2,3,4,6-pentagalloyl-β-D-glucose galloyltransferase is an enzyme found in the leaves of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1-O,6-O-digalloyl-β-D-glucose
1,6-Digalloylglucose, or more specifically 1,6-di-''O''-galloyl-β-D-glucose, is a gallotannin A gallotannin is any of a class of molecules belonging to the hydrolysable tannins. Gallotannins are polymers formed when gallic acid, a polyphenol monomer, esterifies and binds with the hydroxyl group of a polyol carbohydrate such as glucose. Met .... It can be found in some oak species. References Gallotannins {{phenol-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gallic Acid
Gallic acid (also known as 3,4,5-trihydroxybenzoic acid) is a trihydroxybenzoic acid with the formula C6 H2( OH)3CO2H. It is classified as a phenolic acid. It is found in gallnuts, sumac, witch hazel, tea leaves, oak bark, and other plants. It is a white solid, although samples are typically brown owing to partial oxidation. Salts and esters of gallic acid are termed "gallates". Its name is derived from oak galls, which were historically used to prepare tannic acid. Despite the name, gallic acid does not contain gallium. Isolation and derivatives Gallic acid is easily freed from gallotannins by acidic or alkaline hydrolysis. When heated with concentrated sulfuric acid, gallic acid converts to rufigallol. Hydrolyzable tannins break down on hydrolysis to give gallic acid and glucose or ellagic acid and glucose, known as gallotannins and ellagitannins, respectively. Biosynthesis Gallic acid is formed from 3-dehydroshikimate by the action of the enzyme shikimat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1-O-galloyl-β-D-glucose
Glucogallin is chemical compound formed from gallic acid and glucose, β-D-glucose. It can be found in oaks species like the North American white oak (''Quercus alba''), European red oak (''Quercus robur'') and Amla fruit (''Phyllanthus emblica''). It is formed by a gallate 1-beta-glucosyltransferase (UDP-glucose: gallate glucosyltransferase), an enzyme performing the esterification of two substrates, UDP-glucose and gallic acid, gallate to yield two products, Uridine diphosphate, UDP and glucogallin. This enzyme can be found in oak leaf preparations. This the first step in the biosynthesis of gallotannins. The molecule is then used by enzymes in the gallotannins synthetics pathway like beta-glucogallin O-galloyltransferase or beta-glucogallin-tetrakisgalloylglucose O-galloyltransferase. β-Glucogallin is aldose reductase inhibitor. Half-life of β-Glucogallin in human body seems to be unknown. References {{Gallotannin Gallotannins ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Beta-glucogallin O-galloyltransferase
In enzymology, a beta-glucogallin O-galloyltransferase () is an enzyme that catalyzes the chemical reaction :2 1-O-galloyl-beta-D-glucose \rightleftharpoons D-glucose + 1-O,6-O-digalloyl-beta-D-glucose Hence, this enzyme has one substrate, 1-O-galloyl-beta-D-glucose, and two products, D-glucose and 1-O,6-O-digalloyl-beta-D-glucose. This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivi ... of this enzyme class is 1-O-galloyl-beta-D-glucose:1-O-galloyl-beta-D-glucose O-galloyltransferase. References * * EC 2.3.1 Enzymes of unknown structure {{2.3-enzyme-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Digallic Acid
Digallic acid is a polyphenolic compound found in ''Pistacia lentiscus''. Digallic acid is also present in the molecule of tannic acid. Digalloyl esters involve either ''-meta,'' or ''-para'' depside bonds. Tannase is an enzyme that uses digallate to produce gallic acid Gallic acid (also known as 3,4,5-trihydroxybenzoic acid) is a trihydroxybenzoic acid with the formula C6 H2( OH)3CO2H. It is classified as a phenolic acid. It is found in gallnuts, sumac, witch hazel, tea leaves, oak bark, and other plant .... This enzyme can also be used to produce digallic acid from gallotannins. References Gallotannins Trihydroxybenzoic acids Gallate esters Benzoate esters {{aromatic-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Uridine Diphosphate
Uridine diphosphate, abbreviated UDP, is an organic compound. It is an ester of pyrophosphoric acid with the nucleoside uridine. UDP consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase uracil. UDP is an important factor in glycogenesis. Before glucose can be stored as glycogen in the liver and muscles, the enzyme UDP-glucose pyrophosphorylase forms a UDP-glucose unit by combining glucose 1-phosphate with uridine triphosphate, cleaving a pyrophosphate ion in the process. Then, the enzyme glycogen synthase combines UDP-glucose units to form a glycogen chain. The UDP molecule is cleaved from the glucose ring during this process and can be reused by UDP-glucose pyrophosphorylase. See also * DNA * Nucleoside * Nucleotide * Oligonucleotide * RNA Ribonucleic acid (RNA) is a polymeric molecule that is essential for most biological functions, either by performing the function itself (non-coding RNA) or by forming a template for the production of prote ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
UDP-glucose
Uridine diphosphate glucose (uracil-diphosphate glucose, UDP-glucose) is a nucleotide sugar. It is involved in glycosyltransferase reactions in metabolism. Functions UDP-glucose is used in nucleotide sugar metabolism as an activated form of glucose, a substrate for enzymes called glucosyltransferases. UDP-glucose is a precursor of glycogen and can be converted into UDP-galactose and UDP-glucuronic acid, which can then be used as substrates by the enzymes that make polysaccharides containing galactose and glucuronic acid. UDP-glucose can also be used as a precursor of sucrose, lipopolysaccharides and glycosphingolipids. Components UDP-glucose consists of the pyrophosphate group, ribose, glucose, and uracil. See also * DNA * Nucleoside * Nucleotide * Oligonucleotide * RNA * TDP-glucose * Uracil Uracil () (nucleoside#List of nucleosides and corresponding nucleobases, symbol U or Ura) is one of the four nucleotide bases in the nucleic acid RNA. The others are adenine ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
D-glucose
Glucose is a sugar with the molecular formula , which is often abbreviated as Glc. It is overall the most abundant monosaccharide, a subcategory of carbohydrates. It is mainly made by plants and most algae during photosynthesis from water and carbon dioxide, using energy from sunlight. It is used by plants to make cellulose, the most abundant carbohydrate in the world, for use in cell walls, and by all living organisms to make adenosine triphosphate (ATP), which is used by the cell as energy. In energy metabolism, glucose is the most important source of energy in all organisms. Glucose for metabolism is stored as a polymer, in plants mainly as amylose and amylopectin, and in animals as glycogen. Glucose circulates in the blood of animals as blood sugar. The naturally occurring form is -glucose, while its stereoisomer L-glucose, -glucose is produced synthetically in comparatively small amounts and is less biologically active. Glucose is a monosaccharide containing six carbon ato ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
