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Fred J. Ansfield
Fred Joseph Ansfield, M.D. (1910 - 1996) was an American pioneer of medical oncology. He was a leader in applying Fluorouracil, 5-FU (5-Fluorouracil) to humans, demonstrating its effectiveness as a chemotherapy drug. Ansfield co-founded the American Society of Clinical Oncology (ASCO) in 1964, along with Harry Bisel, Arnoldus Goudsmit, Herman H. Freckman, Robert W. Talley, William Wilson and Jane C. WJane Cooke Wright.  He served as ASCO's third president (1966-1967). "He shall be remembered by cancer treatment specialists everywhere as one of the founders of Medical Oncology." Early life Ansfield was born on August 30, 1910, in Milwaukee, Wisconsin. By age 13, both of his parents had died from cancer, steering him towards medicine and cancer research. He attended the University of Wisconsin–Madison, University of Wisconsin, receiving his Bachelor's degree in 1931. During this period he first had the idea to use mice to find a cure for Mammary tumor, mammary cancer in anim ...
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Oncology
Oncology is a branch of medicine that deals with the study, treatment, diagnosis and prevention of cancer. A medical professional who practices oncology is an ''oncologist''. The name's etymological origin is the Greek word ὄγκος (''ónkos''), meaning "tumor", "volume" or "mass". Oncology is concerned with: * The diagnosis of any cancer in a person (pathology) * Therapy (e.g. surgery, chemotherapy, radiotherapy and other modalities) * Follow-up of cancer patients after successful treatment * Palliative care of patients with terminal malignancies * Ethical questions surrounding cancer care * Screening efforts: ** of populations, or ** of the relatives of patients (in types of cancer that are thought to have a hereditary basis, such as breast cancer) Diagnosis Medical histories remain an important screening tool: the character of the complaints and nonspecific symptoms (such as fatigue, weight loss, unexplained anemia, fever of unknown origin, paraneoplastic phe ...
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Silver Star
The Silver Star Medal (SSM) is the United States Armed Forces' third-highest military decoration for valor in combat. The Silver Star Medal is awarded primarily to members of the United States Armed Forces for gallantry in action against an enemy of the United States. History The Silver Star Medal (SSM) is the successor award to the "Citation Star" ( silver star) which was established by an Act of Congress on July 9, 1918, during World War I. On July 19, 1932, the Secretary of War approved the conversion of the "Citation Star" to the SSM with the original "Citation Star" incorporated into the center of the medal. Authorization for the Silver Star Medal was placed into law by an Act of Congress for the U.S. Navy on August 7, 1942, and an Act of Congress for the U.S. Army on December 15, 1942. The current statutory authorization for the medal is Title 10 of the United States Code, for the U.S. Army, for the U.S. Navy and U.S. Marine Corps, and for the U.S. Air Force and ...
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Physicians From Wisconsin
A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the study, diagnosis, prognosis and treatment of disease, injury, and other physical and mental impairments. Physicians may focus their practice on certain disease categories, types of patients, and methods of treatment—known as specialities—or they may assume responsibility for the provision of continuing and comprehensive medical care to individuals, families, and communities—known as general practice. Medical practice properly requires both a detailed knowledge of the academic disciplines, such as anatomy and physiology, underlying diseases and their treatment—the ''science'' of medicine—and also a decent competence in its applied practice—the art or ''craft'' of medicine. Both the role of the physician and the meaning of ...
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Military Personnel From Milwaukee
A military, also known collectively as armed forces, is a heavily armed, highly organized force primarily intended for warfare. It is typically authorized and maintained by a sovereign state, with its members identifiable by their distinct military uniform. It may consist of one or more military branches such as an army, navy, air force, space force, marines, or coast guard. The main task of the military is usually defined as defence of the state and its interests against external armed threats. In broad usage, the terms ''armed forces'' and ''military'' are often treated as synonymous, although in technical usage a distinction is sometimes made in which a country's armed forces may include both its military and other paramilitary forces. There are various forms of irregular military forces, not belonging to a recognized state; though they share many attributes with regular military forces, they are less often referred to as simply ''military''. A nation's military may ...
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Writers From Milwaukee
A writer is a person who uses written words in different writing styles and techniques to communicate ideas. Writers produce different forms of literary art and creative writing such as novels, short stories, books, poetry, travelogues, plays, screenplays, teleplays, songs, and essays as well as other reports and news articles that may be of interest to the general public. Writers' texts are published across a wide range of media. Skilled writers who are able to use language to express ideas well, often contribute significantly to the cultural content of a society. The term "writer" is also used elsewhere in the arts and music, such as songwriter or a screenwriter, but also a stand-alone "writer" typically refers to the creation of written language. Some writers work from an oral tradition. Writers can produce material across a number of genres, fictional or non-fictional. Other writers use multiple media such as graphics or illustration to enhance the communication of ...
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1996 Deaths
File:1996 Events Collage.png, From left, clockwise: A bomb explodes at Centennial Olympic Park in Atlanta, set off by a radical anti-abortionist; The center fuel tank explodes on TWA Flight 800, causing the plane to crash and killing everyone on board; Eight people die in a blizzard on Mount Everest; Dolly the Sheep becomes the first mammal to have been cloned from an adult somatic cell; The Port Arthur Massacre occurs on Tasmania, and leads to major changes in Australia's gun laws; Macarena, sung by Los del Río and remixed by The Bayside Boys, becomes a major dance craze and cultural phenomenon; Ethiopian Airlines Flight 961 crash-ditches off of the Comoros Islands after the plane was hijacked; the 1996 Summer Olympics are held in Atlanta, marking the Centennial (100th Anniversary) of the modern Olympic Games., 300x300px, thumb rect 0 0 200 200 Centennial Olympic Park bombing rect 200 0 400 200 TWA FLight 800 rect 400 0 600 200 1996 Mount Everest disaster rect 0 200 300 400 ...
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1910 Births
Year 191 ( CXCI) was a common year starting on Friday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Apronianus and Bradua (or, less frequently, year 944 ''Ab urbe condita''). The denomination 191 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Parthia * King Vologases IV of Parthia dies after a 44-year reign, and is succeeded by his son Vologases V. China * A coalition of Chinese warlords from the east of Hangu Pass launches a punitive campaign against the warlord Dong Zhuo, who seized control of the central government in 189, and held the figurehead Emperor Xian hostage. After suffering some defeats against the coalition forces, Dong Zhuo forcefully relocates the imperial capital from Luoyang to Chang'an. Before leaving, Dong Zhuo orders his troops to loot the tombs of t ...
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Charles Heidelberger
Charles Heidelberger (December 23, 1920 – January 18, 1983) was a cancer researcher who developed and patented an anticancer drug called 5-Fluorouracil that remains widely used against cancers of the stomach, colon and breast. He was also director of basic research at the University of Southern California's Comprehensive Cancer Center. He received an American Cancer Society National Award in 1974. Heidelberger served on editorial boards of various scientific journals: ''Cancer Research'', '' Molecular Pharmacology'', '' Biochemical Pharmacology'', the '' International Journal of Cancer'', ''In Vitro'', and the ''Journal of Medicinal Chemistry''. He served as director for Basic Research of the USC Cancer Center, and was a Distinguished Professor at the University of Southern California. His former home in Madison, Wisconsin, now known as the Dr. Charles and Judith Heidelberger House, is listed on the National Register of Historic Places. Notable awards and distinctions Heidelb ...
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Cancer Immunotherapy
Cancer immunotherapy (sometimes called immuno-oncology) is the stimulation of the immune system to treat cancer, improving on the immune system's natural ability to fight the disease. It is an application of the fundamental research of cancer immunology and a growing subspecialty of oncology. Cancer immunotherapy exploits the fact that cancer cells often have tumor antigens, molecules on their surface that can be detected by the antibody proteins of the immune system, binding to them. The tumor antigens are often proteins or other macromolecules (e.g., carbohydrates). Normal antibodies bind to external pathogens, but the modified immunotherapy antibodies bind to the tumor antigens marking and identifying the cancer cells for the immune system to inhibit or kill. Clinical success of cancer immunotherapy is highly variable between different forms of cancer; for instance, certain subtypes of gastric cancer react well to the approach whereas immunotherapy is not effective for o ...
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McArdle Laboratory
The McArdle Laboratory for Cancer Research is a basic cancer research facility located on the University of Wisconsin–Madison campus in Madison, Wisconsin. It houses the university's Department of Oncology . The staff of the McArdle Laboratory numbers approximately 200. Twenty-eight faculty members lead research groups focused on various fields such as cancer virology, signal transduction, cell cycle, cancer genetics, and carcinogenesis. Peer-reviewed grants awarded on a competitive basis by agencies such as the National Cancer Institute, Department of Defense, American Cancer Society, and Susan G. Komen for the Cure provide the major source of research funds for the McArdle Laboratory. A small percentage of McArdle’s operating budget is provided by the State of Wisconsin. Private donations and bequests made directly to the McArdle Laboratory play a vital role in the support of the research carried out at the Laboratory. Founding faculty Harold P. Rusch, Roswell Boutwell, ...
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Cancer Therapy
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. While these symptoms may indicate cancer, they can also have other causes. Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor diet, lack of physical activity or excessive drinking of alcohol. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. In the developing world, 15% of cancers are due to infections such as '' Helicobacter pylori'', hepatitis B, hepatitis C, human papillomavirus infection, Epstein–Barr virus and human immunodeficiency virus (HIV). These factors act, at least partly, by changing the genes ...
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Immune System
The immune system is a network of biological processes that protects an organism from diseases. It detects and responds to a wide variety of pathogens, from viruses to parasitic worms, as well as cancer cells and objects such as wood splinters, distinguishing them from the organism's own healthy tissue. Many species have two major subsystems of the immune system. The innate immune system provides a preconfigured response to broad groups of situations and stimuli. The adaptive immune system provides a tailored response to each stimulus by learning to recognize molecules it has previously encountered. Both use molecules and cells to perform their functions. Nearly all organisms have some kind of immune system. Bacteria have a rudimentary immune system in the form of enzymes that protect against virus infections. Other basic immune mechanisms evolved in ancient plants and animals and remain in their modern descendants. These mechanisms include phagocytosis, antimicrobial ...
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