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F Statistics
In population genetics, ''F''-statistics (also known as fixation indices) describe the statistically expected level of Zygosity, heterozygosity in a population; more specifically the expected degree of (usually) a reduction in heterozygosity when compared to Hardy–Weinberg law, Hardy–Weinberg expectation. ''F''-statistics can also be thought of as a measure of the correlation between genes drawn at different levels of a (hierarchically) subdivided population. This correlation is influenced by several evolutionary processes, such as genetic drift, founder effect, population bottleneck, bottleneck, genetic hitchhiking, meiotic drive, mutation, gene flow, inbreeding, natural selection, or the Wahlund effect, but it was originally designed to measure the amount of allelic fixation owing to genetic drift. The concept of ''F''-statistics was developed during the 1920s by the American geneticist Sewall Wright, who was interested in inbreeding in cattle. However, because complete d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
F-test
An ''F''-test is any statistical test in which the test statistic has an ''F''-distribution under the null hypothesis. It is most often used when comparing statistical models that have been fitted to a data set, in order to identify the model that best fits the population from which the data were sampled. Exact "''F''-tests" mainly arise when the models have been fitted to the data using least squares. The name was coined by George W. Snedecor, in honour of Ronald Fisher. Fisher initially developed the statistic as the variance ratio in the 1920s. Common examples Common examples of the use of ''F''-tests include the study of the following cases: * The hypothesis that the means of a given set of normally distributed populations, all having the same standard deviation, are equal. This is perhaps the best-known ''F''-test, and plays an important role in the analysis of variance (ANOVA). * The hypothesis that a proposed regression model fits the data well. See Lack-of-fit sum ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cattle
Cattle (''Bos taurus'') are large, domesticated, cloven-hooved, herbivores. They are a prominent modern member of the subfamily Bovinae and the most widespread species of the genus ''Bos''. Adult females are referred to as cows and adult males are referred to as bulls. Cattle are commonly raised as livestock for meat ( beef or veal, see beef cattle), for milk (see dairy cattle), and for hides, which are used to make leather. They are used as riding animals and draft animals ( oxen or bullocks, which pull carts, plows and other implements). Another product of cattle is their dung, which can be used to create manure or fuel. In some regions, such as parts of India, cattle have significant religious significance. Cattle, mostly small breeds such as the Miniature Zebu, are also kept as pets. Different types of cattle are common to different geographic areas. Taurine cattle are found primarily in Europe and temperate areas of Asia, the Americas, and Australia. Zebus ( ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Scarlet Tiger Moth
The scarlet tiger moth (''Callimorpha dominula'', formerly ''Panaxia dominula'') is a colorful moth belonging to the tiger moth subfamily, Arctiinae. The species was first described by Carl Linnaeus in his 1758 10th edition of ''Systema Naturae''. Subspecies Subspecies within this species include: * ''Callimorpha dominula dominula'' (Linnaeus, 1758) (Baltic, Belarus, Ukraine, Moldova, western Russia and central Europe) * ''Callimorpha dominula lusitanica'' Staudinger, 1894 (Portugal) * ''Callimorpha dominula pompalis'' Nitsche, 926/small> (valleys of the southern Alps) * ''Callimorpha dominula persona'' (Hübner, 1790) (Italy south of the Alps, excluding Piedmont and southern Alpine valleys) * ''Callimorpha dominula trinacriae'' Nardelli & Giandolfo, 1996 (Sicily) * ''Callimorpha dominula profuga'' (Goeze, 1781) (Balkans: Macedonia (Scopje); Albania; Greece; western Turkey) * ''Callimorpha dominula rossica'' Kolenati, 1846 (Caucasus, Transcaucasia, except Talysh Mountains; north ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Identity By Descent
A DNA segment is identical by state (IBS) in two or more individuals if they have identical nucleotide sequences in this segment. An IBS segment is identical by descent (IBD) in two or more individuals if they have inherited it from a common ancestor without recombination, that is, the segment has the same ancestral origin in these individuals. DNA segments that are IBD are IBS per definition, but segments that are not IBD can still be IBS due to the same mutations in different individuals or recombinations that do not alter the segment. Theory All individuals in a finite population are related if traced back long enough and will, therefore, share segments of their genomes IBD. During meiosis segments of IBD are broken up by recombination. Therefore, the expected length of an IBD segment depends on the number of generations since the most recent common ancestor at the locus of the segment. The length of IBD segments that result from a common ancestor ''n'' generations in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene Locus
In genetics, a locus (plural loci) is a specific, fixed position on a chromosome where a particular gene or genetic marker is located. Each chromosome carries many genes, with each gene occupying a different position or locus; in humans, the total number of protein-coding genes in a complete haploid set of 23 chromosomes is estimated at 19,000–20,000. Genes may possess multiple variants known as alleles, and an allele may also be said to reside at a particular locus. Diploid and polyploid cells whose chromosomes have the same allele at a given locus are called homozygous with respect to that locus, while those that have different alleles at a given locus are called heterozygous. The ordered list of loci known for a particular genome is called a gene map. Gene mapping is the process of determining the specific locus or loci responsible for producing a particular phenotype or biological trait. Association mapping, also known as "linkage disequilibrium mapping", is a method of ma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Allele Frequencies
Allele frequency, or gene frequency, is the relative frequency of an allele (variant of a gene) at a particular locus in a population, expressed as a fraction or percentage. Specifically, it is the fraction of all chromosomes in the population that carry that allele over the total population or sample size. Microevolution is the change in allele frequencies that occurs over time within a population. Given the following: # A particular locus on a chromosome and a given allele at that locus # A population of ''N'' individuals with ploidy ''n'', i.e. an individual carries ''n'' copies of each chromosome in their somatic cells (e.g. two chromosomes in the cells of diploid species) # The allele exists in ''i'' chromosomes in the population then the allele frequency is the fraction of all the occurrences ''i'' of that allele and the total number of chromosome copies across the population, ''i''/(''nN''). The allele frequency is distinct from the genotype frequency, although they are r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hardy–Weinberg Principle
In population genetics, the Hardy–Weinberg principle, also known as the Hardy–Weinberg equilibrium, model, theorem, or law, states that allele and genotype frequencies in a population will remain constant from generation to generation in the absence of other evolutionary influences. These influences include ''genetic drift'', '' mate choice'', ''assortative mating'', ''natural selection'', ''sexual selection'', ''mutation'', ''gene flow'', '' meiotic drive'', ''genetic hitchhiking'', ''population bottleneck'', ''founder effect,'' ''inbreeding and outbreeding depression''. In the simplest case of a single locus with two alleles denoted ''A'' and ''a'' with frequencies and , respectively, the expected genotype frequencies under random mating are for the AA homozygotes, for the aa homozygotes, and for the heterozygotes. In the absence of selection, mutation, genetic drift, or other forces, allele frequencies ''p'' and ''q'' are constant between generations, so equilibriu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Expected Value
In probability theory, the expected value (also called expectation, expectancy, mathematical expectation, mean, average, or first moment) is a generalization of the weighted average. Informally, the expected value is the arithmetic mean of a large number of independently selected outcomes of a random variable. The expected value of a random variable with a finite number of outcomes is a weighted average of all possible outcomes. In the case of a continuum of possible outcomes, the expectation is defined by integration. In the axiomatic foundation for probability provided by measure theory, the expectation is given by Lebesgue integration. The expected value of a random variable is often denoted by , , or , with also often stylized as or \mathbb. History The idea of the expected value originated in the middle of the 17th century from the study of the so-called problem of points, which seeks to divide the stakes ''in a fair way'' between two players, who have to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Observation
Observation is the active acquisition of information from a primary source. In living beings, observation employs the senses. In science, observation can also involve the perception and recording of data via the use of scientific instruments. The term may also refer to any data collected during the scientific activity. Observations can be qualitative, that is, only the absence or presence of a property is noted, or quantitative if a numerical value is attached to the observed phenomenon by counting or measuring. Science The scientific method requires observations of natural phenomena to formulate and test hypotheses. It consists of the following steps: # Ask a question about a natural phenomenon # Make observations of the phenomenon # Formulate a hypothesis that tentatively answers the question # Predict logical, observable consequences of the hypothesis that have not yet been investigated # Test the hypothesis' predictions by an experiment, observational study, field study ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coefficient Of Relationship
The coefficient of relationship is a measure of the degree of consanguinity (or biological relationship) between two individuals. The term coefficient of relationship was defined by Sewall Wright in 1922, and was derived from his definition of the coefficient of inbreeding of 1921. The measure is most commonly used in genetics and genealogy. A coefficient of inbreeding can be calculated for an individual, and is typically one-half the coefficient of relationship between the parents. In general, the higher the level of inbreeding the closer the coefficient of relationship between the parents approaches a value of 1, expressed as a percentage, and approaches a value of 0 for individuals with arbitrarily remote common ancestors. Coefficient of relationship The coefficient of relationship ( r ) between two individuals B and C is obtained by a summation of coefficients calculated for every line by which they are connected to their common ancestors. Each such line connects the two i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fixation Index
The fixation index (FST) is a measure of population differentiation due to genetic structure. It is frequently estimated from genetic polymorphism data, such as single-nucleotide polymorphisms (SNP) or microsatellites. Developed as a special case of Wright's F-statistics, it is one of the most commonly used statistics in population genetics. Definition Two of the most commonly used definitions for FST at a given locus are based on 1) the variance of allele frequencies between populations, and on 2) the probability of Identity by descent. If \bar is the average frequency of an allele in the total population, \sigma^2_S is the variance in the frequency of the allele between different subpopulations, weighted by the sizes of the subpopulations, and \sigma^2_T is the variance of the allelic state in the total population, FST is defined as : F_ = \frac = \frac Wright's definition illustrates that FST measures the amount of genetic variance that can be explained by population stru ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Effective Population Size
The effective population size (''N''''e'') is a number that, in some simplified scenarios, corresponds to the number of breeding individuals in the population. More generally, ''N''''e'' is the number of individuals that an idealised population would need to have in order for some specified quantity of interest (typically change of genetic diversity or inbreeding rates) to be the same as in the real population. Idealised populations are based on unrealistic but convenient simplifications such as random mating, simultaneous birth of each new generation, constant population size, and equal numbers of children per parent. For most quantities of interest and most real populations, the effective population size ''N''''e'' is usually smaller than the census population size ''N'' of a real population. The same population may have multiple effective population sizes, for different properties of interest, including for different genetic loci. The effective population size is most commonly ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
