Firing Pattern
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Firing Pattern
Neural oscillations, or brainwaves, are rhythmic or repetitive patterns of neural activity in the central nervous system. Neural tissue can generate oscillatory activity in many ways, driven either by mechanisms within individual neurons or by interactions between neurons. In individual neurons, oscillations can appear either as oscillations in membrane potential or as rhythmic patterns of action potentials, which then produce oscillatory activation of post-synaptic neurons. At the level of neural ensembles, synchronized activity of large numbers of neurons can give rise to macroscopic oscillations, which can be observed in an electroencephalogram. Oscillatory activity in groups of neurons generally arises from feedback connections between the neurons that result in the synchronization of their firing patterns. The interaction between neurons can give rise to oscillations at a different frequency than the firing frequency of individual neurons. A well-known example of macros ...
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Brain Imaging
Neuroimaging is the use of quantitative (computational) techniques to study the structure and function of the central nervous system, developed as an objective way of scientifically studying the healthy human brain in a non-invasive manner. Increasingly it is also being used for quantitative research studies of brain disease and psychiatric illness. Neuroimaging is highly multidisciplinary involving neuroscience, computer science, psychology and statistics, and is not a medical specialty. Neuroimaging is sometimes confused with neuroradiology. Neuroradiology is a medical specialty that uses non-statistical brain imaging in a clinical setting, practiced by radiologists who are medical practitioners. Neuroradiology primarily focuses on recognizing brain lesions, such as vascular diseases, strokes, tumors, and inflammatory diseases. In contrast to neuroimaging, neuroradiology is qualitative (based on subjective impressions and extensive clinical training) but sometimes uses basic q ...
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Pink Noise
Pink noise, noise, fractional noise or fractal noise is a signal (information theory), signal or process with a frequency spectrum such that the power spectral density (power per frequency interval) is inversely proportional to the frequency of the signal. In pink noise, each Octave (electronics), octave interval (halving or doubling in frequency) carries an equal amount of noise energy. Pink noise sounds like a waterfall. It is often used to tune loudspeaker systems in professional audio. Pink noise is one of the most commonly observed signals in biological systems. The name arises from the pink appearance of visible light with this power spectrum. This is in contrast with white noise which has equal intensity per frequency interval. Definition Within the scientific literature, the term "1/f noise" is sometimes used loosely to refer to any noise with a power spectral density of the form S(f) \propto \frac, where is frequency, and , with exponent usually close to 1. On ...
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Phase (waves)
In physics and mathematics, the phase (symbol φ or ϕ) of a wave or other periodic function F of some real variable t (such as time) is an angle-like quantity representing the fraction of the cycle covered up to t. It is expressed in such a scale that it varies by one full turn as the variable t goes through each period (and F(t) goes through each complete cycle). It may be measured in any angular unit such as degrees or radians, thus increasing by 360° or 2\pi as the variable t completes a full period. This convention is especially appropriate for a sinusoidal function, since its value at any argument t then can be expressed as \varphi(t), the sine of the phase, multiplied by some factor (the amplitude of the sinusoid). (The cosine may be used instead of sine, depending on where one considers each period to start.) Usually, whole turns are ignored when expressing the phase; so that \varphi(t) is also a periodic function, with the same period as F, that repeatedly ...
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Amplitude
The amplitude of a periodic variable is a measure of its change in a single period (such as time or spatial period). The amplitude of a non-periodic signal is its magnitude compared with a reference value. There are various definitions of amplitude (see below), which are all functions of the magnitude of the differences between the variable's extreme values. In older texts, the phase of a periodic function is sometimes called the amplitude. Definitions Peak amplitude and semi-amplitude For symmetric periodic waves, like sine waves or triangle waves, ''peak amplitude'' and ''semi amplitude'' are the same. Peak amplitude In audio system measurements, telecommunications and others where the measurand is a signal that swings above and below a reference value but is not sinusoidal, peak amplitude is often used. If the reference is zero, this is the maximum absolute value of the signal; if the reference is a mean value ( DC component), the peak amplitude is the maximum ab ...
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Frequency
Frequency is the number of occurrences of a repeating event per unit of time. Frequency is an important parameter used in science and engineering to specify the rate of oscillatory and vibratory phenomena, such as mechanical vibrations, audio signals (sound), radio waves, and light. The interval of time between events is called the period. It is the reciprocal of the frequency. For example, if a heart beats at a frequency of 120 times per minute (2 hertz), its period is one half of a second. Special definitions of frequency are used in certain contexts, such as the angular frequency in rotational or cyclical properties, when the rate of angular progress is measured. Spatial frequency is defined for properties that vary or cccur repeatedly in geometry or space. The unit of measurement of frequency in the International System of Units (SI) is the hertz, having the symbol Hz. Definitions and units For cyclical phenomena such as oscillations, waves, or for examp ...
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Local Field Potentials
Local field potentials (LFP) are transient electrical signals generated in nerves and other tissues by the summed and synchronous electrical activity of the individual cells (e.g. neurons) in that tissue. LFP are "extracellular" signals, meaning that they are generated by transient imbalances in ion concentrations in the spaces outside the cells, that result from cellular electrical activity. LFP are 'local' because they are recorded by an electrode placed nearby the generating cells. As a result of the Inverse-square law, such electrodes can only 'see' potentials in a spatially limited radius. They are 'potentials' because they are generated by the voltage that results from charge separation in the extracellular space. They are 'field' because those extracellular charge separations essentially create a local electric field. LFP are typically recorded with a high-impedance microelectrode placed in the midst of the population of cells generating it. They can be recorded, for exam ...
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Action Potential
An action potential (also known as a nerve impulse or "spike" when in a neuron) is a series of quick changes in voltage across a cell membrane. An action potential occurs when the membrane potential of a specific Cell (biology), cell rapidly rises and falls. This depolarization then causes adjacent locations to similarly depolarize. Action potentials occur in several types of Membrane potential#Cell excitability, excitable cells, which include animal cells like neurons and myocyte, muscle cells, as well as some plant cells. Certain endocrine cells such as pancreatic beta cells, and certain cells of the anterior pituitary gland are also excitable cells. In neurons, action potentials play a central role in cell–cell interaction, cell–cell communication by providing for—or with regard to saltatory conduction, assisting—the propagation of signals along the neuron's axon toward axon terminal, synaptic boutons situated at the ends of an axon; these signals can then connect wit ...
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Evoked Potential
An evoked potential or evoked response is an electrical potential in a specific pattern recorded from a specific part of the nervous system, especially the brain, of a human or other animals following presentation of a stimulus such as a light flash or a pure tone. Different types of potentials result from stimuli of different modalities and types. Evoked potential is distinct from spontaneous potentials as detected by electroencephalography (EEG), electromyography (EMG), or other electrophysiologic recording method. Such potentials are useful for electrodiagnosis and monitoring that include detections of disease and drug-related sensory dysfunction and intraoperative monitoring of sensory pathway integrity. Evoked potential amplitudes tend to be low, ranging from less than a microvolt to several microvolts, compared to tens of microvolts for EEG, millivolts for EMG, and often close to 20 millivolts for ECG. To resolve these low-amplitude potentials against the background of ...
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Vladimir Pravdich-Neminsky
Vladimir Pravdich-Neminsky (, ; 2 July 1879 – 17 May 1952) was a Ukrainian physiologist who published the first EEG and the evoked potential of the mammalian brain. He was a representative of Kyiv Physiological School. He was a victim of Soviet repressions. Life Family Vladimir Pravdich-Neminsky was born in Kyiv in Polish-Ukrainian aristocratic family of Neminsky of Prawdzic coat of arms. His father Volodymyr Stanislavovych had a rank of Active State Councillor. He owned 309 dessiatines (approximately 320 hectares or 850 acres) of farmland in Ivashkivtsi village in Podolia Governorate. In the beginning of the 20th century he lent it to local farmers. Little is known of Volodymyr Stanislavovych origin. There was an officer called Stanislav Neminsky (born 1809) in Russian Caucasian army in 1849 but it is unknown whether he is of any relation to Volodymyr. From 1901 to 1911, Volodymyr Stanislavovych worked as an officer in a chancery of Kyiv Land Bank. In 1899, he owned a ...
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Adolf Beck (physiologist)
Adolf Abraham Beck (1 January 1863, Kraków – August 1942, Lviv) was a Polish physician and professor of physiology at the University of Lviv. He is considered one of the pioneers of electroencephalography (EEG). Life and career He was born on 1 January 1863, in Kraków, Galicia (Central Europe), Galicia, into a poor Jewish family. During his academic career, Beck supported himself as a tutor, private tutor. Upon graduating with distinction from the gymnasium of his native city in 1884, he entered the Jagiellonian University in Kraków. In 1888, while still a medical student, Beck gained the prize of the university by a paper on the excitability of a nerve, afterward published under the title, "O pobudliwości różnych miejsc tego samego nerwu" (On the Excitability of a Nerve at Different Points). In 1890 he received the degree of Doctor of Medicine, M.D., and in the same year published the results of his extensive research on electrical processes in the brain. His papers ...
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