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Filoviridae
''Filoviridae'' () is a International Committee on Taxonomy of Viruses, family of RNA virus#Group_V_–_negative-sense_ssRNA_viruses, single-stranded negative-sense RNA viruses in the order (biology), order ''Mononegavirales''. Two members of the family that are commonly known are Zaire ebolavirus, Ebola virus and Marburg virus. Both viruses, and some of their lesser known relatives, cause severe disease in humans and nonhuman primates in the form of viral hemorrhagic fevers. All filoviruses are classified by the US as select agents, by the World Health Organization as Risk Group 4 Pathogens (requiring Biosafety, Biosafety Level 4-equivalent containment), by the National Institutes of Health/National Institute of Allergy and Infectious Diseases as Category A Priority Pathogens, and by the Centers for Disease Control and Prevention as Bioterrorism, Category A Bioterrorism Agents, and are listed as Biological Agents for Export Control by the Australia Group. Use of term The Interna ...
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Marburgvirus
The genus ''Marburgvirus'' is the taxonomic home of ''Marburg marburgvirus'', whose members are the two known marburgviruses, Marburg virus (MARV) and Ravn virus (RAVV). Both viruses cause Marburg virus disease in humans and nonhuman primates, a form of viral hemorrhagic fever. Both are select agents, World Health Organization Risk Group 4 Pathogens (requiring Biosafety Level 4-equivalent containment), National Institutes of Health/ National Institute of Allergy and Infectious Diseases Category A Priority Pathogens, Centers for Disease Control and Prevention Category A Bioterrorism Agents, and are listed as Biological Agents for Export Control by the Australia Group. Use of term The genus ''Marburgvirus'' is a virological taxon included in the family '' Filoviridae'', order '' Mononegavirales''. The genus currently includes a single virus species, '' Marburg marburgvirus''. The members of the genus (i.e. the actual physical entities) are called marburgviruses. The n ...
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Marburg Virus
Marburg virus (MARV) is a hemorrhagic fever virus of the '' Filoviridae'' family of viruses and a member of the species '' Marburg marburgvirus'', genus '' Marburgvirus''. It causes Marburg virus disease in primates, a form of viral hemorrhagic fever. The World Health Organization (WHO) rates it as a Risk Group 4 Pathogen (requiring biosafety level 4-equivalent containment). In the United States, the National Institute of Allergy and Infectious Diseases ranks it as a Category A Priority Pathogen and the Centers for Disease Control and Prevention lists it as a Category A Bioterrorism Agent. It is also listed as a biological agent for export control by the Australia Group. The virus can be transmitted by exposure to one species of fruit bats or it can be transmitted between people via body fluids through unprotected sex and broken skin. The disease can cause haemorrhage, fever, and other symptoms similar to Ebola, which belongs to the same family of viruses. According to t ...
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Ebolavirus
The genus ''Ebolavirus'' (- or ; - or ) is a International Committee on Taxonomy of Viruses, virological taxon included in the family ''Filoviridae'' (filament-shaped viruses), order ''Mononegavirales''. The members of this genus are called ebolaviruses, and encode their genome in the form of RNA virus#Group V—negative-sense ssRNA viruses, single-stranded negative-sense RNA. The six known virus International Committee on Taxonomy of Viruses, species are named for the region where each was originally identified: ''Bundibugyo ebolavirus'', ''Reston ebolavirus'', ''Sudan ebolavirus'', ''Taï Forest ebolavirus'' (originally ''Côte d'Ivoire ebolavirus''), ''Zaire ebolavirus'', and ''Bombali ebolavirus''. The last is the most recent species to be named and was isolated from Angolan free-tailed bats in Sierra Leone. Each species of the genus ''Ebolavirus'' has one member virus, and four of these cause Ebola virus disease (EVD) in humans, a type of Viral hemorrhagic fever, hemorrhagic ...
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Zaire Ebolavirus
''Orthoebolavirus zairense'' or Zaire ebolavirus, more commonly known as Ebola virus (; EBOV), is one of six known species within the genus ''Ebolavirus''. Four of the six known ebolaviruses, including EBOV, cause a severe and often fatal hemorrhagic fever in humans and other mammals, known as Ebola virus disease (EVD). Ebola virus has caused the majority of human deaths from EVD, and was the cause of the 2013–2016 epidemic in western Africa, which resulted in at least suspected cases and confirmed deaths. Ebola virus and its genus were both originally named for Zaire (now the Democratic Republic of the Congo), the country where it was first described, and was at first suspected to be a new "strain" of the closely related Marburg virus. The virus was renamed "Ebola virus" in 2010 to avoid confusion. Ebola virus is the single member of the species ''Zaire ebolavirus'', which is assigned to the genus ''Ebolavirus'', family ''Filoviridae'', order ''Mononegavirales''. The me ...
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Cuevavirus
The species ''Lloviu cuevavirus'' ( ) is the taxonomic home of a virus that forms filamentous virion, ''Lloviu virus'' (LLOV). The species is included in the genus '' Cuevavirus''. LLOV is a distant relative of the commonly known Ebola virus and Marburg virus. Use of term The species ''Lloviu cuevavirus'' is a virological taxon (i.e. a man-made concept) included in the genus '' Cuevavirus'', family '' Filoviridae'', order '' Mononegavirales''. The species has a single virus member, Lloviu virus. Lloviu virus is the sole member of the species ''Lloviu cuevavirus'', which is included genus '' Cuevavirus'', family '' Filoviridae'', order '' Mononegavirales''. The name Lloviu virus is derived from ''Cueva del Lloviu'' (the name of a Spanish cave in which it was first discovered) and the taxonomic suffix ''virus'' (which denotes a virus species). In 2010, the species and the genus '' cuevavirus'' were proposed as independent species and genus. In July 2013, the species and the ...
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Dianlovirus
''Mengla dianlovirus'' (MLAV, also written ''Měnglà virus'') is a type of filovirus identified in a ''Rousettus'' bat in Mengla County, Yunnan Province, China, and was first reported in January 2019. It is classified in the same family as ''Ebolavirus'' and ''Marburgvirus''. It is the only member of the genus ''Dianlovirus''. The name derives from (), the Chinese language abbreviation for Yunnan, added to "filovirus", the common name for ''Filoviridae ''Filoviridae'' () is a International Committee on Taxonomy of Viruses, family of RNA virus#Group_V_–_negative-sense_ssRNA_viruses, single-stranded negative-sense RNA viruses in the order (biology), order ''Mononegavirales''. Two members of the ...''. Neither the species nor the genus are listed in the 2018 ICTV classification, as the virus was formally described after that report was released. A formal proposal was submitted for the taxa in January 2019. MLAV proteins, including VP35 and VP40, inhibit host immune re ...
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Viral Hemorrhagic Fever
Viral hemorrhagic fevers (VHFs) are a diverse group of diseases. "Viral" means a health problem caused by infection from a virus, " hemorrhagic" means to bleed, and "fever" means an unusually high body temperature. Bleeding and fever are common signs of VHFs, which is how the group of infections got its common name. There are five known families of RNA viruses which cause VHFs: '' Arenaviridae'', '' Filoviridae'', '' Flaviviridae'', '' Hantaviridae'', and ''Rhabdoviridae''. Some VHFs are usually mild, such as nephropathia epidemica (within the family ''Hantaviridae''). But some are usually severe and have a high death rate, such as Ebola virus (within the family ''Filoviridae''). All VHFs can potentially cause severe blood loss, high fever, and death. Both humans and non human animals can be infected. Signs and symptoms The following are signs and symptoms of most or all VHFs. * Circulatory shock *Diarrhea (feces which resemble more liquid than solid) *Headache *Hypotens ...
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Mononegavirales
''Mononegavirales'' is an order of negative-strand RNA viruses which have nonsegmented genomes. Some members that cause human disease in this order include Ebola virus, human respiratory syncytial virus, measles virus, mumps virus, Nipah virus, and rabies virus. Important pathogens of nonhuman animals and plants are also in the group. The order includes eleven virus families: '' Artoviridae'', '' Bornaviridae'', ''Filoviridae'', '' Lispiviridae'', '' Mymonaviridae'', '' Nyamiviridae'', ''Paramyxoviridae'', '' Pneumoviridae'', ''Rhabdoviridae'', '' Sunviridae'', and '' Xinmoviridae''. Use of term The order ''Mononegavirales'' (pronounced: ) According to the rules for taxon naming established by the International Committee on Taxonomy of Viruses (ICTV), the name ''Mononegavirales'' is always to be capitalized, italicized, and never abbreviated. The names of the order's physical members ("mononegaviruses" or "mononegavirads") are to be written in lower case, are not italicized, ...
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RNA Virus
An RNA virus is a virus characterized by a ribonucleic acid (RNA) based genome. The genome can be single-stranded RNA (ssRNA) or double-stranded (Double-stranded RNA, dsRNA). Notable human diseases caused by RNA viruses include influenza, SARS, MERS, COVID-19, Dengue virus, hepatitis C, hepatitis E, West Nile fever, Ebola virus disease, rabies, polio, mumps, and measles. All known RNA viruses, that is viruses that use a homologous RNA-dependent polymerase for replication, are categorized by the International Committee on Taxonomy of Viruses (ICTV) into the realm ''Riboviria''. This includes RNA viruses belonging to ''Group III'', ''Group IV'' or ''Group V'' of the Virus classification#Baltimore classification, Baltimore classification system as well as ''Group VI. Group VI'' viruses are retroviruses, viruses with RNA genetic material that use DNA intermediates in their Viral life cycle, life cycle including HIV-1 and HIV-2 which cause AIDS. The majority of such RNA viruses fall ...
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Virus
A virus is a submicroscopic infectious agent that replicates only inside the living Cell (biology), cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Viruses are found in almost every ecosystem on Earth and are the most numerous type of biological entity. Since Dmitri Ivanovsky's 1892 article describing a non-bacterial pathogen infecting tobacco plants and the discovery of the tobacco mosaic virus by Martinus Beijerinck in 1898, more than 16,000 of the millions of List of virus species, virus species have been described in detail. The study of viruses is known as virology, a subspeciality of microbiology. When infected, a host cell is often forced to rapidly produce thousands of copies of the original virus. When not inside an infected cell or in the process of infecting a cell, viruses exist in the form of independent viral particles, or ''virions'', consisting of (i) genetic material, i.e., long ...
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Bioterrorism
Bioterrorism is terrorism involving the intentional release or dissemination of biological agents. These agents include bacteria, viruses, insects, fungi, and/or their toxins, and may be in a naturally occurring or a human-modified form, in much the same way as in biological warfare. Further, modern agribusiness is vulnerable to anti-agricultural attacks by terrorists, and such attacks can seriously damage economy as well as consumer confidence. The latter destructive activity is called agrobioterrorism and is a subtype of agro-terrorism. Definition Bioterrorism agents are typically found in nature, but could be mutated or altered to increase their ability to cause disease, make them resistant to current medicines, or to increase their ability to be spread into the environment. Biological agents can be spread through the air, water, or in food. Biological agents are attractive to terrorists because they are extremely difficult to detect and do not cause illness for severa ...
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Suffix
In linguistics, a suffix is an affix which is placed after the stem of a word. Common examples are case endings, which indicate the grammatical case of nouns and adjectives, and verb endings, which form the conjugation of verbs. Suffixes can carry grammatical information (inflectional endings) or lexical information ( derivational/lexical suffixes)''.'' Inflection changes the grammatical properties of a word within its syntactic category. Derivational suffixes fall into two categories: class-changing derivation and class-maintaining derivation. Particularly in the study of Semitic languages, suffixes are called affirmatives, as they can alter the form of the words. In Indo-European studies, a distinction is made between suffixes and endings (see Proto-Indo-European root). A word-final segment that is somewhere between a free morpheme and a bound morpheme is known as a suffixoidKremer, Marion. 1997. ''Person reference and gender in translation: a contrastive investigation of ...
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