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Filarioidea
The Filarioidea are a superfamily of highly specialised parasitic nematodes. Species within this superfamily are known as filarial worms or filariae (singular filaria). Infections with parasitic filarial worms cause disease conditions generically known as filariasis. Drugs against these worms are known as filaricides. Introduction Filarioidea all are specialised parasites and the definitive host is always a vertebrate, a mammal, bird, reptile or amphibian, but ''not'' a fish. The intermediate host is always an arthropod. Most of Filarioidea parasitise wild species, birds in particular, but some, especially in the family Onchocercidae, attack mammals, including humans and some domestic animals. Conditions that result from parasitism by Onchocercidae include some of the most troublesome diseases of the warmer regions, including river blindness and elephantiasis. Taxonomy The Filarioidea include several families: * Aproctidae * Creagrocercidae * Drilonematidae *Filariidae * ...
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Brugia Malayi
''Brugia malayi'' is a filarial (arthropod-borne) nematode (roundworm), one of the three causative agents of lymphatic filariasis in humans. Lymphatic filariasis, also known as elephantiasis, is a condition characterized by swelling of the lower limbs. The two other filarial causes of lymphatic filariasis are '' Wuchereria bancrofti'' and ''Brugia timori'', which both differ from ''B. malayi'' morphologically, symptomatically, and in geographical extent. ''B. malayi'' is transmitted by '' Mansonia'' mosquitoes and is restricted to South and Southeast Asia. It is one of the tropical diseases targeted for elimination by the year 2020 by the World Health Organization, which has spurred vaccine and drug development, as well as new methods of vector control. Signs and symptoms ''B. malayi'' is one of the causative agents of lymphatic filariasis, a condition marked by infection and swelling of the lymphatic system. The disease is primarily caused by the presence of worms in the lym ...
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Brugia Timori
''Brugia timori'' is a filarial (arthropod-borne) nematode (roundworm) which causes the disease "Timor filariasis", or "Timorian filariasis". While this disease was first described in 1965, the identity of ''Brugia timori'' as the causative agent was not known until 1977. In that same year, ''Anopheles barbirostris'' was shown to be its primary vector. There is no known animal reservoir host. Signs and symptoms Like other human filariasis infections, ''Brugia timori'' filariasis causes acute fever and chronic lymphedema. The life cycle of ''Brugia timori'' is very similar to that of '' Wuchereria bancrofti'' and '' Brugia malayi'', leading to nocturnal periodicity of the disease symptoms. Eosinophilia is common during acute stages of infection. So far ''Brugia timori'' has only been found in the Lesser Sunda Islands of Indonesia. It is locally confined to areas inhabited by its mosquito vector, which breeds in rice fields. One study of the prevalence of infection in ...
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Parasitism
Parasitism is a Symbiosis, close relationship between species, where one organism, the parasite, lives on or inside another organism, the Host (biology), host, causing it some harm, and is Adaptation, adapted structurally to this way of life. The entomologist E. O. Wilson has characterised parasites as "predators that eat prey in units of less than one". Parasites include single-celled protozoans such as the agents of malaria, sleeping sickness, and amoebic dysentery; animals such as hookworms, lice, mosquitoes, and vampire bats; fungi such as Armillaria mellea, honey fungus and the agents of ringworm; and plants such as mistletoe, dodder, and the Orobanchaceae, broomrapes. There are six major parasitic Behavioral ecology#Evolutionarily stable strategy, strategies of exploitation of animal hosts, namely parasitic castration, directly transmitted parasitism (by contact), wikt:trophic, trophicallytransmitted parasitism (by being eaten), Disease vector, vector-transmitted paras ...
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Loa Loa
''Loa loa'' is a filarial (arthropod-borne) nematode (roundworm) that causes ''Loa loa'' filariasis. ''Loa loa'' actually means "worm worm", but is commonly known as the "eye worm", as it localizes to the conjunctiva of the eye. ''Loa loa'' is commonly found in Africa.Schmidt, Gerald et al. "Foundations of Parasitology". 7th ed. McGraw Hill, New York, NY, 2005. It mainly inhabits rain forests in West Africa and has native origins in Ethiopia. The disease caused by ''Loa loa'' is called loiasis and is one of the neglected tropical diseases. ''L. loa'' is one of three parasitic filarial nematodes that cause subcutaneous filariasis in humans. The other two are '' Mansonella streptocerca and Onchocerca volvulus'' (causes river blindness). Maturing larvae and adults of the "eye worm" occupy the subcutaneous layer of the skin – the fat layer – of humans, causing disease. The ''L. loa'' adult worm which travels under the skin can survive up to 10–15 years, causing infl ...
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Creagrocercidae
Creagrocercidae is a family of nematodes belonging to the order Spirurida Spirurida is an order of spirurian nematodes. Like all nematodes, they have neither a circulatory nor a respiratory system. Some Spirurida, like the genus '' Gongylonema'', can cause disease in humans. One such disease is a skin infection wi .... Genera: * '' Creagrocercus'' Baylis, 1943 References Nematodes {{chromadorea-stub ...
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Mansonella Streptocerca
''Mansonella streptocerca'', (formerly ''Diptalonema streptocerca''), is a filarial (arthropod-borne) nematode (roundworm) causing the disease streptocerciasis. It is a common parasite in the skin of humans in the rain forests of Africa, where it is thought to be a parasite of chimpanzees, as well. ''Mansonella streptocerca'' is one of three filarial nematodes that cause subcutaneous filariasis in humans. The other two filarial nematodes are '' Loa loa'' (the African eye worm), and '' Onchocerca volvulus'' (river blindness). The worm is distributed across West and Central Africa. Life cycle The contraction of an ''M. streptocerca'' infection can be better understood through an understanding of its life cycle. The life cycle involves two stages: one involving a midge (genus '' Culicoides'') and another involving a human host. First, a midge ingests a blood meal from a human host. This allows third-stage filarial larvae to enter the bite wound. Once inside the dermis, the ...
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Loa Loa Filariasis
''Loa loa'' filariasis is a skin and eye disease caused by the nematode worm ''Loa loa''. Humans contract this disease through the bite of a deer fly or mango fly (''Chrysops'' spp.), the vectors for ''Loa loa''. The adult ''Loa loa'' filarial worm migrates throughout the subcutaneous tissues of humans, occasionally crossing into subconjunctival tissues of the eye where it can be easily observed. ''Loa loa'' does not normally affect one's vision but can be painful when moving about the eyeball or across the bridge of the nose.John, David T. and William A. Petri, Jr. Markell and Voge's Medical Parasitology. 9th ed. 2006. The disease can cause red itchy swellings below the skin called "Calabar swellings". The disease is treated with the drug diethylcarbamazine (DEC), and when appropriate, surgical methods may be employed to remove adult worms from the conjunctiva. Loiasis belongs to the so-called neglected diseases. Signs and symptoms A filariasis such as loiasis most often con ...
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Wuchereria Bancrofti
''Wuchereria bancrofti'' is a filarial (arthropod-borne) nematode (roundworm) that is the major cause of lymphatic filariasis. It is one of the three parasitic worms, together with ''Brugia malayi'' and '' B. timori'', that infect the lymphatic system to cause lymphatic filariasis. These filarial worms are spread by a variety of mosquito vector species. ''W. bancrofti'' is the most prevalent of the three and affects over 120 million people, primarily in Central Africa and the Nile delta, South and Central America, the tropical regions of Asia including southern China, and the Pacific islands. If left untreated, the infection can develop into lymphatic filariasis. In rare conditions, it also causes tropical pulmonary eosinophilia. No vaccine is commercially available, but high rates of cure have been achieved with various antifilarial regimens and lymphatic filariasis is the target of the World Health Organization Global Program to Eliminate Lymphatic Filariasis with the aim to ...
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Disease
A disease is a particular abnormal condition that negatively affects the structure or function of all or part of an organism, and that is not immediately due to any external injury. Diseases are often known to be medical conditions that are associated with specific signs and symptoms. A disease may be caused by external factors such as pathogens or by internal dysfunctions. For example, internal dysfunctions of the immune system can produce a variety of different diseases, including various forms of immunodeficiency, hypersensitivity, allergies and autoimmune disorders. In humans, ''disease'' is often used more broadly to refer to any condition that causes pain, dysfunction, distress, social problems, or death to the person affected, or similar problems for those in contact with the person. In this broader sense, it sometimes includes injuries, disabilities, disorders, syndromes, infections, isolated symptoms, deviant behaviors, and atypical variations of stru ...
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Pathogen
In biology, a pathogen ( el, πάθος, "suffering", "passion" and , "producer of") in the oldest and broadest sense, is any organism or agent that can produce disease. A pathogen may also be referred to as an infectious agent, or simply a germ. The term ''pathogen'' came into use in the 1880s. Typically, the term ''pathogen'' is used to describe an ''infectious'' microorganism or agent, such as a virus, bacterium, protozoan, prion, viroid, or fungus. Small animals, such as helminths and insects, can also cause or transmit disease. However, these animals are usually referred to as parasites rather than pathogens. The scientific study of microscopic organisms, including microscopic pathogenic organisms, is called microbiology, while parasitology refers to the scientific study of parasites and the organisms that host them. There are several pathways through which pathogens can invade a host. The principal pathways have different episodic time frames, but soil has the ...
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Microfilaria Of Dirofilaria Immitis (Heartworms) Surrounded By Neoplastic Lymphocytes 1
::''Microfilaria may also refer to an informal "collective group" genus name, proposed by Cobbold in 1882. While a convenient category for newly discovered microfilariae which can not be assigned to a known species because the adults are unknown, it is seldom used today.'' The microfilaria (plural microfilariae, sometimes abbreviated mf) is an early stage in the life cycle of certain parasitic nematodes in the family Onchocercidae. In these species, the adults live in a tissue or the circulatory system of vertebrates (the "definitive hosts"). They release microfilariae into the bloodstream of the vertebrate host. The microfilariae are taken up by blood-feeding arthropod vectors (the "intermediate hosts"). In the intermediate host the microfilariae develop into infective larvae that can be transmitted to a new vertebrate host. The presence of microfilariae in the host bloodstream is called "microfilaraemia". The success of filariasis eradication programs is typically gauged ...
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Ungellidae
Ungellidae is a family of nematodes belonging to the order Rhabditida Rhabditida is an order of free-living, zooparasitic, and phytoparasitic microbivorous nematodes living in soil. The Cephalobidae, Panagrolaimidae, Steinernematidae, and Strongyloididae seem to be closer to the Tylenchia, regardless of whethe .... Genera Genera: * '' Acanthungella'' Ivanova & Hope, 2004 * '' Adungella'' Timm, 1967 * '' Chabaudigella'' Ivanova & Bain, 2012 References {{Taxonbar, from=Q18711952 Nematodes ...
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