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Elvin A. Kabat
Elvin Abraham Kabat (September 1, 1914 – June 16, 2000) was an American biomedical scientist and one of the founding fathers of modern quantitative immunochemistry. Kabat was awarded the Louisa Gross Horwitz Prize from Columbia University in 1977 and the National Medal of Science in 1991. He is the father of Jon Kabat-Zinn. Elvin A. Kabat was the president of the American Association of Immunologists from 1965 to 1966, a member of the National Academy of Sciences and a fellow of the American Academy of Arts and Sciences. He laid the foundations of the Kabat numbering scheme, a scheme for the numbering of amino acid residues in antibodies based upon variable regions. In 1969, he started collecting and aligning amino acid sequences of human and mouse Bence Jones proteins and immunoglobulin light chains in 1969. In 1995 he was awarded the American Association of Immunologists Lifetime Achievement Award. Work Kabat was instrumental in the discovery of the structural and genetic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Elvin Kabat
Elvin Abraham Kabat (September 1, 1914 – June 16, 2000) was an American biomedical scientist and one of the founding fathers of modern quantitative immunochemistry. Kabat was awarded the Louisa Gross Horwitz Prize from Columbia University in 1977 and the National Medal of Science in 1991. He is the father of Jon Kabat-Zinn. Elvin A. Kabat was the president of the American Association of Immunologists from 1965 to 1966, a member of the National Academy of Sciences and a fellow of the American Academy of Arts and Sciences. He laid the foundations of the Kabat numbering scheme, a scheme for the numbering of amino acid residues in antibodies based upon variable regions. In 1969, he started collecting and aligning amino acid sequences of human and mouse Bence Jones proteins and immunoglobulin light chains in 1969. In 1995 he was awarded the American Association of Immunologists Lifetime Achievement Award. Work Kabat was instrumental in the discovery of the structural and genet ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heterogeneity
Homogeneity and heterogeneity are concepts often used in the sciences and statistics relating to the uniformity of a substance or organism. A material or image that is homogeneous is uniform in composition or character (i.e. color, shape, size, weight, height, distribution, texture, language, income, disease, temperature, radioactivity, architectural design, etc.); one that is heterogeneous is distinctly nonuniform in at least one of these qualities. Heterogeneous Mixtures, in chemistry, is where certain elements are unwillingly combined and, when given the option, will separate. Etymology and spelling The words ''homogeneous'' and ''heterogeneous'' come from Medieval Latin ''homogeneus'' and ''heterogeneus'', from Ancient Greek ὁμογενής (''homogenēs'') and ἑτερογενής (''heterogenēs''), from ὁμός (''homos'', “same”) and ἕτερος (''heteros'', “other, another, different”) respectively, followed by γένος (''genos'', “kind”); - ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electrophoresis
Electrophoresis, from Ancient Greek ἤλεκτρον (ḗlektron, "amber") and φόρησις (phórēsis, "the act of bearing"), is the motion of dispersed particles relative to a fluid under the influence of a spatially uniform electric field. Electrophoresis of positively charged particles ( cations) is sometimes called cataphoresis, while electrophoresis of negatively charged particles (anions) is sometimes called anaphoresis. The electrokinetic phenomenon of electrophoresis was observed for the first time in 1807 by Russian professors Peter Ivanovich Strakhov and Ferdinand Frederic Reuss at Moscow University, who noticed that the application of a constant electric field caused clay particles dispersed in water to migrate. It is ultimately caused by the presence of a charged interface between the particle surface and the surrounding fluid. It is the basis for analytical techniques used in chemistry for separating molecules by size, charge, or binding affinity. Electrop ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Uppsala, Sweden
Uppsala (, or all ending in , ; archaically spelled ''Upsala'') is the county seat of Uppsala County and the fourth-largest city in Sweden, after Stockholm, Gothenburg, and Malmö. It had 177,074 inhabitants in 2019. Located north of the capital Stockholm it is also the seat of Uppsala Municipality. Since 1164, Uppsala has been the ecclesiastical centre of Sweden, being the seat of the Archbishop of the Church of Sweden. Uppsala is home to Scandinavia's largest cathedral – Uppsala Cathedral, which was the frequent site of the coronation of the Swedish monarch until the late 19th century. Uppsala Castle, built by King Gustav Vasa, served as one of the royal residences of the Swedish monarchs, and was expanded several times over its history, making Uppsala the secondary capital of Sweden during its greatest extent. Today it serves as the residence of the Governor of Uppsala County. Founded in 1477, Uppsala University is the oldest centre of higher education in Scandinavia ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Arne Tiselius
Arne Wilhelm Kaurin Tiselius (10 August 1902 – 29 October 1971) was a Swedish biochemist who won the Nobel Prize in Chemistry in 1948 "for his research on electrophoresis and adsorption analysis, especially for his discoveries concerning the complex nature of the serum proteins." Education Tiselius was born in Stockholm. Following the death of his father, the family moved to Gothenburg where he went to school, and after graduation at the local "Realgymnasium" in 1921, he studied at the Uppsala University, specializing in chemistry. Career and research Tiselius became a research assistant at Theodor Svedberg's laboratory in 1925 and obtained his doctoral degree in 1930 on the moving-boundary method of studying the electrophoresis of proteins. From then to 1935 he published a number of papers on diffusion and adsorption in naturally occurring base-exchanging zeolites, and these studies continued during a year's visit to Hugh Stott Taylor's laboratory in Princeton Universit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Columbia University College Of Physicians And Surgeons
Columbia University Vagelos College of Physicians and Surgeons (VP&S) is the graduate medical school of Columbia University, located at the Columbia University Irving Medical Center in the Washington Heights neighborhood of Manhattan. Founded in 1767 by Samuel Bard as the medical department of King's College (now Columbia University), VP&S was the first medical school in the Thirteen Colonies to award the Doctor of Medicine (MD) degree. Beginning in 1993, VP&S was also the first U.S. medical school to hold a white coat ceremony. According to '' U.S. News & World Report'', VP&S is one of the most selective medical schools in the United States based on average MCAT score, GPA, and acceptance rate. In 2018, 7,537 people applied and 1,007 were interviewed for 140 seats in its entering MD class. The median undergraduate GPA and average MCAT score for successful applicants in 2014 were 3.82 and 36, respectively. Columbia is third for research among American medical schools by '' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Michael Heidelberger
Michael Heidelberger (April 29, 1888 – June 25, 1991) was an American immunologist, often regarded as the father of modern immunology. He and Oswald Avery showed that the polysaccharides of pneumococcus are antigens, enabling him to show that antibodies are proteins. He spent most his early career at Columbia University and comparable time in his later years on the faculty of New York University. In 1934 and 1936 he received the Guggenheim Fellowship. In 1967 he received the National Medal of Science, and then he earned the Lasker Award for basic medical research in 1953 and again in 1978. His papers are held at the National Library of Medicine in Bethesda, Maryland. Early life Heidelberger was born in 1888 in New York City to a Jewish couple, David and Fannie Campe Heidelberger, a traveling salesman and a homemaker respectively. An older brother had died shortly after birth; a younger brother, Charles, was born 21 months after Michael. His paternal grandfather, also named Mi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemistry
Chemistry is the scientific study of the properties and behavior of matter. It is a natural science that covers the elements that make up matter to the compounds made of atoms, molecules and ions: their composition, structure, properties, behavior and the changes they undergo during a reaction with other substances. Chemistry also addresses the nature of chemical bonds in chemical compounds. In the scope of its subject, chemistry occupies an intermediate position between physics and biology. It is sometimes called the central science because it provides a foundation for understanding both basic and applied scientific disciplines at a fundamental level. For example, chemistry explains aspects of plant growth ( botany), the formation of igneous rocks ( geology), how atmospheric ozone is formed and how environmental pollutants are degraded ( ecology), the properties of the soil on the moon ( cosmochemistry), how medications work ( pharmacology), and how to collec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
City College Of New York
The City College of the City University of New York (also known as the City College of New York, or simply City College or CCNY) is a public university within the City University of New York (CUNY) system in New York City. Founded in 1847, City College was the first free public institution of higher education in the United States. It is the oldest of CUNY's 25 institutions of higher learning, and is considered its flagship college. Located in Hamilton Heights overlooking Harlem in Manhattan, City College's 35-acre (14 ha) Collegiate Gothic campus spans Convent Avenue from 130th to 141st Streets. It was initially designed by renowned architect George B. Post, and many of its buildings have achieved landmark status. The college has graduated ten Nobel Prize winners, one Fields Medalist, one Turing Award winner, three Pulitzer Prize winners, and three Rhodes Scholars. Among these alumni, the latest is a Bronx native, John O'Keefe (2014 Nobel Prize in Medicine). City Colleg ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
New York City
New York, often called New York City or NYC, is the most populous city in the United States. With a 2020 population of 8,804,190 distributed over , New York City is also the most densely populated major city in the United States, and is more than twice as populous as second-place Los Angeles. New York City lies at the southern tip of New York State, and constitutes the geographical and demographic center of both the Northeast megalopolis and the New York metropolitan area, the largest metropolitan area in the world by urban landmass. With over 20.1 million people in its metropolitan statistical area and 23.5 million in its combined statistical area as of 2020, New York is one of the world's most populous megacities, and over 58 million people live within of the city. New York City is a global cultural, financial, entertainment, and media center with a significant influence on commerce, health care and life sciences, research, technology, education, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Leukocyte
White blood cells, also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders. All white blood cells are produced and derived from multipotent cells in the bone marrow known as hematopoietic stem cells. Leukocytes are found throughout the body, including the blood and lymphatic system. All white blood cells have nuclei, which distinguishes them from the other blood cells, the anucleated red blood cells (RBCs) and platelets. The different white blood cells are usually classified by cell lineage (myeloid cells or lymphoid cells). White blood cells are part of the body's immune system. They help the body fight infection and other diseases. Types of white blood cells are granulocytes (neutrophils, eosinophils, and basophils), and agranulocytes (monocytes, and lymphocytes (T cells and B cells)). Myeloid cells ( myelocytes) include neutrophils, eosinophils, mast cells, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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