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Entrainment (chronobiology)
In the study of chronobiology, entrainment refers to the synchronization of a biological clock to an environmental cycle. An example is the interaction between circadian rhythms and environmental cues, such as light and temperature. Entrainment helps organisms adapt their bodily processes according to the timing of a changing environment. For example, entrainment is manifested during travel between time zones, hence why humans experience jet lag. Biological rhythms are endogenous; they persist even in the absence of environmental cues as they are driven by an internal mechanism, most notably the circadian clock. Of the several possible cues (known as '' zeitgebers,'' German for 'time-givers') that can contribute to entrainment of the circadian clock, light has the greatest impact. Units of circadian time (CT) are used to describe entrainment to refer to the relationship between the rhythm and the light signal/pulse. Modes of entrainment There are two general modes of entrainm ...
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Chronobiology
Chronobiology is a field of biology that examines timing processes, including periodic (cyclic) phenomena in living organisms, such as their adaptation to solar- and lunar-related rhythms. These cycles are known as biological rhythms. Chronobiology comes from the ancient Greek χρόνος (''chrónos'', meaning "time"), and biology, which pertains to the study, or science, of life. The related terms ''chronomics'' and ''chronome'' have been used in some cases to describe either the molecular mechanisms involved in chronobiological phenomena or the more quantitative aspects of chronobiology, particularly where comparison of cycles between organisms is required. Chronobiological studies include but are not limited to comparative anatomy, physiology, genetics, molecular biology and behavior of organisms related to their biological rhythms. Other aspects include epigenetics, development, reproduction, ecology and evolution. The subject Chronobiology studies variations of t ...
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Liver
The liver is a major metabolic organ (anatomy), organ exclusively found in vertebrates, which performs many essential biological Function (biology), functions such as detoxification of the organism, and the Protein biosynthesis, synthesis of various proteins and various other Biochemistry, biochemicals necessary for digestion and growth. In humans, it is located in the quadrants and regions of abdomen, right upper quadrant of the abdomen, below the thoracic diaphragm, diaphragm and mostly shielded by the lower right rib cage. Its other metabolic roles include carbohydrate metabolism, the production of a number of hormones, conversion and storage of nutrients such as glucose and glycogen, and the decomposition of red blood cells. Anatomical and medical terminology often use the prefix List of medical roots, suffixes and prefixes#H, ''hepat-'' from ἡπατο-, from the Greek language, Greek word for liver, such as hepatology, and hepatitis The liver is also an accessory digestive ...
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Diurnality
Diurnality is a form of plant and ethology, animal behavior characterized by activity during daytime, with a period of sleeping or other inactivity at night. The common adjective used for daytime activity is "diurnal". The timing of activity by an animal depends on a variety of environmental factors such as the temperature, the ability to gather food by sight, the risk of predation, and the time of year. Diurnality is a cycle of activity within a 24-hour period; cyclic activities called circadian rhythms are endogenous cycles not dependent on external cues or environmental factors except for a zeitgeber. Animals active during twilight are crepuscular, those active during the night are nocturnal and animals active at sporadic times during both night and day are cathemerality, cathemeral. Plants that open their flowers during the daytime are described as diurnal, while those that bloom during nighttime are nocturnal. The timing of flower opening is often related to the time at whic ...
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Crepuscular
In zoology, a crepuscular animal is one that is active primarily during the twilight period, being matutinal (active during dawn), vespertine (biology), vespertine/vespertinal (active during dusk), or both. This is distinguished from diurnality, diurnal and nocturnality, nocturnal behavior, where an animal is active during the hours of daytime and of night, respectively. Some crepuscular animals may also be active by moonlight or during an overcast day. Matutinal animals are active only after dawn, and vespertine (biology), vespertine only before dusk. A number of factors affect the time of day an animal is active. Predation, Predators hunt when their prey is available, and prey try to avoid the times when their principal predators are at large. The temperature may be too high at midday or too low at night. Some creatures may adjust their activities depending on local competition. Etymology and usage The word ''crepuscular'' derives from the Latin ''wiktionary:crepusculum, cre ...
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Non-24-hour Sleep–wake Disorder
Non-24-hour sleep–wake disorder (non-24, N24SWD, or N24) is one of several chronic circadian rhythm sleep disorders (CRSDs). It is defined as a "chronic steady pattern comprising ..daily delays in sleep onset and wake times in an individual living in a society". Symptoms result when the non-entrained ( free-running) endogenous circadian rhythm drifts out of alignment with the light–dark cycle in nature. Although this sleep disorder is more common in blind people, affecting up to 70% of the totally blind, it can also affect sighted people. Non-24 may also be comorbid with bipolar disorder, depression, and traumatic brain injury. The American Academy of Sleep Medicine (AASM) has provided CRSD guidelines since 2007 with the latest update released in 2015. People with non-24 experience daily shifts in the circadian rhythm such as peak time of alertness, body temperature minimum, metabolism and hormone secretion. These shifts do not align with the natural light–dark cycle. ...
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Advanced Sleep Phase Disorder
Advanced Sleep Phase Disorder (ASPD), also known as the advanced sleep-phase type (ASPT) of circadian rhythm sleep disorder, is a condition that is characterized by a recurrent pattern of early evening (e.g. 7-9 PM) sleepiness and very early morning awakening (e.g. 2-4 AM). This sleep phase advancement can interfere with daily social and work schedules, and results in shortened sleep duration and excessive daytime sleepiness. The timing of sleep and melatonin levels are regulated by the body's central circadian clock, which is located in the suprachiasmatic nucleus in the hypothalamus. Symptoms Individuals with ASPD report being unable to stay awake until conventional bedtime, falling asleep too quickly and/or early in the evening, and being unable to stay asleep until their desired waking time, experiencing early morning insomnia. When someone has advanced sleep phase disorder their melatonin levels and core body temperature cycle hours earlier than an average person. These sympt ...
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Delayed Sleep Phase Disorder
Delayed sleep phase disorder (DSPD), more often known as delayed sleep phase syndrome and also as delayed sleep–wake phase disorder, is the delaying of a person's circadian rhythm (biological clock) compared to those of societal norms. The disorder affects the timing of biological rhythms including sleep, peak period of alertness, core body temperature, and hormonal cycles. People with this disorder are often called night owls. The diagnosis of this disorder is currently a point of contention among specialists of sleep disorders. Many insomnia-related disorders can present significantly differently between patients, and circadian rhythm disorders and melatonin related disorders are not well understood by modern medical science. The orexin system was only identified in 1998, yet it appears intimately implicated in human sleep-wake systems. Evidence for the plasticity of human circadian rhythm cycles has been provided by multiple studies. In one example, several dozen volun ...
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Chronotype
A chronotype is the behavioral manifestation of an underlying circadian rhythm's myriad of physical processes. A person's chronotype is the propensity for the individual to sleep at a particular time during a 24-hour period. ''Eveningness'' (delayed sleep period; most active and alert in the evening) and ''morningness'' (advanced sleep period; most active and alert in the morning) are the two extremes with most individuals having some flexibility in the timing of their sleep period. However, across development there are changes in the propensity of the sleep period with pre-pubescent children preferring an advanced sleep period, adolescents preferring a delayed sleep period and many elderly preferring an advanced sleep period. Humans are normally diurnal creatures that are active in the daytime. As with most other diurnal animals, human activity-rest patterns are endogenously regulated by biological clocks with a circadian (~24-hour) period. Chronotypes have also been investigat ...
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Sleep Hygiene
Sleep hygiene is a behavioral and environmental practice developed in the late 1970s as a method to help people with mild to moderate insomnia. Clinicians assess the sleep hygiene of people with insomnia and other conditions, such as depression, and offer recommendations based on the assessment. Sleep hygiene recommendations include establishing a regular sleep schedule, using naps with care, not exercising physically (or mentally) too close to bedtime, limiting worry, limiting exposure to light in the hours before sleep, getting out of bed if sleep does not come, not using bed for anything but sleep and sex, avoiding alcohol (as well as nicotine, caffeine, and other stimulants) in the hours before bedtime, and having a peaceful, comfortable and dark sleep environment. Assessment Assessment of sleep hygiene includes a clinical interview and self-report questionnaires and sleep diaries, which are typically kept from one to two weeks, to record a representative sample data. T ...
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Pendulum Clocks
A pendulum clock is a clock that uses a pendulum, a swinging weight, as its timekeeping element. The advantage of a pendulum for timekeeping is that it is an approximate harmonic oscillator: It swings back and forth in a precise time interval dependent on its length, and resists swinging at other rates. From its invention in 1656 by Christiaan Huygens, inspired by Galileo Galilei, until the 1930s, the pendulum clock was the world's most precise timekeeper, accounting for its widespread use. Throughout the 18th and 19th centuries, pendulum clocks in homes, factories, offices, and railroad stations served as primary time standards for scheduling daily life, work shifts, and public transportation. Their greater accuracy allowed for the faster pace of life which was necessary for the Industrial Revolution. The home pendulum clock was replaced by less-expensive synchronous electric clocks in the 1930s and 1940s. Pendulum clocks are now kept mostly for their decorative and antique val ...
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Peripheral Oscillators
A peripheral device, or simply peripheral, is an auxiliary hardware device that a computer uses to transfer information externally. A peripheral is a hardware component that is accessible to and controlled by a computer but is not a core component of the computer. A peripheral can be categorized based on the direction in which information flows relative to the computer: * The computer receives data from an ''input device''; examples: mouse, keyboard, scanner, game controller, microphone and webcam * The computer sends data to an ''output device''; examples: monitor, printer, headphones, and speakers * The computer sends and receives data via an ''input/output device''; examples: storage device (such as disk drive, solid-state drive, USB flash drive, memory card and tape drive), modem, router, gateway and network adapter Many modern electronic devices, such as Internet-enabled digital watches, video game consoles, smartphones, and tablet computers, have interfaces for u ...
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Heart
The heart is a muscular Organ (biology), organ found in humans and other animals. This organ pumps blood through the blood vessels. The heart and blood vessels together make the circulatory system. The pumped blood carries oxygen and nutrients to the tissue, while carrying metabolic waste such as carbon dioxide to the lungs. In humans, the heart is approximately the size of a closed fist and is located between the lungs, in the middle compartment of the thorax, chest, called the mediastinum. In humans, the heart is divided into four chambers: upper left and right Atrium (heart), atria and lower left and right Ventricle (heart), ventricles. Commonly, the right atrium and ventricle are referred together as the right heart and their left counterparts as the left heart. In a healthy heart, blood flows one way through the heart due to heart valves, which prevent cardiac regurgitation, backflow. The heart is enclosed in a protective sac, the pericardium, which also contains a sma ...
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