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Enterovirus 68
Enterovirus D68 (EV-D68) is a member of the '' Picornaviridae'' family, an enterovirus. First isolated in California in 1962 and once considered rare, it has been on a worldwide upswing in the 21st century. It is suspected of causing a polio-like disorder called acute flaccid myelitis (AFM). Virology EV-D68 is one of the more than one hundred types of enteroviruses, a group of ssRNA viruses containing the polioviruses, coxsackieviruses, and echoviruses. It is unenveloped. Unlike all other enteroviruses, EV-D68 displays acid lability and a lower optimum growth temperature, both characteristic features of the human rhinoviruses. It was previously called human rhinovirus 87 by some researchers. Since the year 2000, the original virus strains diversified and evolved a genetically distinct outbreak strain, clade B1. It is Clade B1, but not older strains, which has been associated with AFM and is neuropathic in animal models. Epidemiology Since its discovery in 1962, EV-D68 ...
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Picornaviridae
Picornaviruses are a group of related nonenveloped RNA viruses which infect vertebrates including fish, mammals, and birds. They are viruses that represent a large family of small, positive-sense, single-stranded RNA viruses with a 30 nm icosahedral capsid. The viruses in this family can cause a range of diseases including the common cold, poliomyelitis, meningitis, hepatitis, and paralysis. Picornaviruses constitute the family ''Picornaviridae'', order '' Picornavirales'', and realm ''Riboviria''. There are 159 species in this family, assigned to 68 genera, most of which belong to 5 subfamilies. Notable examples are genera ''Enterovirus'' (including ''Rhinovirus'' and ''Poliovirus''), '' Aphthovirus'', '' Cardiovirus'', and '' Hepatovirus''. Etymology The name "picornavirus" has a dual etymology. Firstly, the name derives from ''picorna''- which is an acronym for "''p''oliovirus, ''i''nsensitivity to ether, ''c''oxsackievirus, ''o''rphan virus, ''r''hinovirus, and ...
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Polio-like Syndrome
Polio-like syndrome is a general description of a group of symptoms which mimic polio, including rarely permanent paralysis. Various triggers have been found, including some viruses from the same virus group as polio: enterovirus 68, enterovirus 71, and coxsackievirus A7. These are suspected in many cases of acute flaccid myelitis. Other non-virus causes of polio-like symptoms are observed, though rarely, from snake bite, spider bite, scorpion sting, tick bite, or chemicals such as arsenic Arsenic is a chemical element; it has Symbol (chemistry), symbol As and atomic number 33. It is a metalloid and one of the pnictogens, and therefore shares many properties with its group 15 neighbors phosphorus and antimony. Arsenic is not ... and organophosphorus insecticides. References Polio Syndromes {{nervoussystem-disease-stub ...
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Respiratory Illness
Respiratory diseases, or lung diseases, are pathological conditions affecting the organs and tissues that make gas exchange difficult in air-breathing animals. They include conditions of the respiratory tract including the trachea, bronchi, bronchioles, alveoli, pleurae, pleural cavity, the nerves and muscles of respiration. Respiratory diseases range from mild and self-limiting, such as the common cold, influenza, and pharyngitis to life-threatening diseases such as bacterial pneumonia, pulmonary embolism, tuberculosis, acute asthma, lung cancer, and severe acute respiratory syndromes, such as COVID-19. Respiratory diseases can be classified in many different ways, including by the organ or tissue involved, by the type and pattern of associated signs and symptoms, or by the cause of the disease. The study of respiratory disease is known as pulmonology. A physician who specializes in respiratory disease is known as a pulmonologist, a chest medicine specialist, a respiratory med ...
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Respiratory Disease
Respiratory diseases, or lung diseases, are pathological conditions affecting the organs and tissues that make gas exchange difficult in air-breathing animals. They include conditions of the respiratory tract including the trachea, bronchi, bronchioles, alveoli, pleurae, pleural cavity, the nerves and muscles of respiration. Respiratory diseases range from mild and self-limiting, such as the common cold, influenza, and pharyngitis to life-threatening diseases such as bacterial pneumonia, pulmonary embolism, tuberculosis, acute asthma, lung cancer, and severe acute respiratory syndromes, such as COVID-19. Respiratory diseases can be classified in many different ways, including by the organ or tissue involved, by the type and pattern of associated signs and symptoms, or by the cause of the disease. The study of respiratory disease is known as pulmonology. A physician who specializes in respiratory disease is known as a pulmonologist, a chest medicine specialist, a r ...
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Immunosuppression
Immunosuppression is a reduction of the activation or efficacy of the immune system. Some portions of the immune system itself have immunosuppressive effects on other parts of the immune system, and immunosuppression may occur as an adverse reaction to treatment of other conditions. In general, deliberately induced immunosuppression is performed to prevent the body from rejecting an organ transplant. Additionally, it is used for treating graft-versus-host disease after a bone marrow transplant, or for the treatment of auto-immune diseases such as systemic lupus erythematosus, rheumatoid arthritis, Sjögren's syndrome, or Crohn's disease. This is typically done using medications, but may involve surgery (splenectomy), plasmapheresis, or radiation. A person who is undergoing immunosuppression, or whose immune system is weak for some other reasons (such as chemotherapy or HIV), is said to be ''immunocompromised''. Deliberately induced Administration of immunosuppressive medi ...
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Asthma
Asthma is a common long-term inflammatory disease of the airways of the lungs. It is characterized by variable and recurring symptoms, reversible airflow obstruction, and easily triggered bronchospasms. Symptoms include episodes of wheezing, coughing, chest tightness, and shortness of breath. A sudden worsening of asthma symptoms sometimes called an 'asthma attack' or an 'asthma exacerbation' can occur when allergens, pollen, dust, or other particles, are inhaled into the lungs, causing the bronchioles to constrict and produce mucus, which then restricts oxygen flow to the alveoli. These may occur a few times a day or a few times per week. Depending on the person, asthma symptoms may become worse at night or with exercise. Asthma is thought to be caused by a combination of genetic and environmental factors. Environmental factors include exposure to air pollution and allergens. Other potential triggers include medications such as aspirin and beta blockers. Diag ...
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Northern Hemisphere
The Northern Hemisphere is the half of Earth that is north of the equator. For other planets in the Solar System, north is defined by humans as being in the same celestial sphere, celestial hemisphere relative to the invariable plane of the Solar System as Earth's North Pole. Due to Earth's axial tilt of 23.439281°, there is a seasonal variation in the lengths of the day and night. There is also a seasonal variation in temperatures, which lags the variation in day and night. Conventionally, winter in the Northern Hemisphere is taken as the period from the December solstice (typically December 21 UTC) to the March equinox (typically March 20 UTC), while summer is taken as the period from the June solstice through to the September equinox (typically on 23 September UTC). The dates vary each year due to the difference between the calendar year and the Year#Astronomical years, astronomical year. Within the Northern Hemisphere, oceanic currents can change the weather patterns that aff ...
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Autumn Equinox (Northern Hemisphere)
The September equinox (or southward equinox) is the moment when the Sun appears to cross the celestial equator, heading southward. Because of differences between the calendar year and the tropical year, the September equinox may occur from September 21 to 24. At the equinox, the Sun as viewed from the equator rises due east and sets due west. Before the Southward equinox, the Sun rises and sets more northerly, and afterwards, it rises and sets more southerly. The equinox may be taken to mark the end of astronomical summer and the beginning of astronomical autumn (autumnal equinox) in the Northern Hemisphere, while marking the end of astronomical winter and the start of astronomical spring (vernal equinox) in the Southern Hemisphere. Occurrences The September equinox is one point in time commonly used to determine the length of the tropical year. The dates and times of the September equinoxes that occur from the year 2018 to 2028 (UTC) are listed as follows: Constella ...
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Spring Equinox (Northern Hemisphere)
The March equinox or northward equinox is the equinox on the Earth when the subsolar point appears to leave the Southern Hemisphere and cross the celestial equator, heading northward as seen from Earth. The March equinox is known as the vernal equinox (or spring equinox) in the Northern Hemisphere and as the autumnal equinox (or fall equinox) in the Southern Hemisphere. On the Gregorian calendar at 0° longitude, the northward equinox can occur as early as 19 March (which happened most recently in 1796, and will happen next in 2044), and it can occur as late as 21 March (which happened most recently in 2007, and will happen next in 2102). For a common year the computed time slippage is about 5 hours 49 minutes ''later'' than the previous year, and for a leap year about 18 hours 11 minutes ''earlier'' than the previous year. Balancing the increases of the common years against the losses of the leap years keeps the calendar date of the March equinox from drifting more than one ...
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Spain
Spain, or the Kingdom of Spain, is a country in Southern Europe, Southern and Western Europe with territories in North Africa. Featuring the Punta de Tarifa, southernmost point of continental Europe, it is the largest country in Southern Europe and the fourth-most populous European Union member state. Spanning across the majority of the Iberian Peninsula, its territory also includes the Canary Islands, in the Eastern Atlantic Ocean, the Balearic Islands, in the Western Mediterranean Sea, and the Autonomous communities of Spain#Autonomous cities, autonomous cities of Ceuta and Melilla, in mainland Africa. Peninsular Spain is bordered to the north by France, Andorra, and the Bay of Biscay; to the east and south by the Mediterranean Sea and Gibraltar; and to the west by Portugal and the Atlantic Ocean. Spain's capital and List of largest cities in Spain, largest city is Madrid, and other major List of metropolitan areas in Spain, urban areas include Barcelona, Valencia, Seville, ...
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Norway
Norway, officially the Kingdom of Norway, is a Nordic countries, Nordic country located on the Scandinavian Peninsula in Northern Europe. The remote Arctic island of Jan Mayen and the archipelago of Svalbard also form part of the Kingdom of Norway. Bouvet Island, located in the Subantarctic, is a Dependencies of Norway, dependency, and not a part of the Kingdom; Norway also Territorial claims in Antarctica, claims the Antarctic territories of Peter I Island and Queen Maud Land. Norway has a population of 5.6 million. Its capital and largest city is Oslo. The country has a total area of . The country shares a long eastern border with Sweden, and is bordered by Finland and Russia to the northeast. Norway has an extensive coastline facing the Skagerrak strait, the North Atlantic Ocean, and the Barents Sea. The unified kingdom of Norway was established in 872 as a merger of Petty kingdoms of Norway, petty kingdoms and has existed continuously for years. From 1537 to 1814, Norway ...
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Sweden
Sweden, formally the Kingdom of Sweden, is a Nordic countries, Nordic country located on the Scandinavian Peninsula in Northern Europe. It borders Norway to the west and north, and Finland to the east. At , Sweden is the largest Nordic country by both area and population, and is the List of European countries by area, fifth-largest country in Europe. Its capital and largest city is Stockholm. Sweden has a population of 10.6 million, and a low population density of ; 88% of Swedes reside in urban areas. They are mostly in the central and southern half of the country. Sweden's urban areas together cover 1.5% of its land area. Sweden has a diverse Climate of Sweden, climate owing to the length of the country, which ranges from 55th parallel north, 55°N to 69th parallel north, 69°N. Sweden has been inhabited since Prehistoric Sweden, prehistoric times around 12,000 BC. The inhabitants emerged as the Geats () and Swedes (tribe), Swedes (), who formed part of the sea-faring peopl ...
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