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Eli Moschcowitz
Eli Moschcowitz (2 August 1879 – 23 February 1964) was an American doctor best known for his role in discovering thrombotic thrombocytopenic purpura (TTP), which was originally called "Moschcowitz syndrome". He is also known for having an early role in the development of psychosomatic medicine. Early life Moschcowitz was born to a Jewish family in Girált, Hungary. Career Moschcowitz received a medical degree from Columbia University College of Physicians and Surgeons. He spent much of his career as a pathologist at Beth Israel Medical Center in Manhattan, and was later medical director of Mount Sinai Hospital (Manhattan) and Professor of Clinical Medicine at Columbia. He was also a Diplomate of the American Board of Internal Medicine. In 1925 Moschcowitz described the autopsy pathology of a young female patient who died of a disease that first caused petechiae, pallor, paralysis, and coma. Her blood vessels were largely filled with platelets. Modern reports still occasionally ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Giraltovce
Giraltovce ( hu, Girált, rue, Ґіралтівцї) is a town in the Prešov Region of eastern Slovakia. History The town was first mentioned in 1383 as ''Giralth''. It was named after a man called Geralth who was first hereditary scultetus (a locator serving a noble in founding a new village). The town was founded in the 13th century. In 1427 it was the property of the Széchy family, a few years later it belonged to the Somosy family. The scultetus had a leading role in the village. They acted as the representative of the village before the landlords, regional and religious authorities. They controlled villagers to pay their taxes. Moreover, they had also right of minor magistracy. Their rights were more restricted by changes in the 16th century. In the 17th century, the institution of hereditary scultetus in the village expired. Since that moment, local villagers voted their Chief Magistrate ("Richter"). The most privileged part of inhabitants of the village was nobility, w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
World Chess Champion
The World Chess Championship is played to determine the world champion in chess. The current world champion is Magnus Carlsen of Norway, who has held the title since 2013. The first event recognized as a world championship was the 1886 match between the two leading players in the world, Wilhelm Steinitz and Johannes Zukertort. Steinitz won, becoming the first world champion. From 1886 to 1946, the champion set the terms, requiring any challenger to raise a sizable stake and defeat the champion in a match in order to become the new world champion. Following the death of reigning world champion Alexander Alekhine in 1946, FIDE (the International Chess Federation) took over administration of the World Championship, beginning with the 1948 World Championship tournament. From 1948 to 1993, FIDE organized a set of tournaments to choose a new challenger every three years. In 1993, reigning champion Garry Kasparov broke away from FIDE, which led to a rival claimant to the title of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jewish Hungarian Scientists
Jews ( he, יְהוּדִים, , ) or Jewish people are an ethnoreligious group and nation originating from the Israelites Israelite origins and kingdom: "The first act in the long drama of Jewish history is the age of the Israelites""The people of the Kingdom of Israel and the ethnic and religious group known as the Jewish people that descended from them have been subjected to a number of forced migrations in their history" and Hebrews of historical Israel and Judah. Jewish ethnicity, nationhood, and religion are strongly interrelated, "Historically, the religious and ethnic dimensions of Jewish identity have been closely interwoven. In fact, so closely bound are they, that the traditional Jewish lexicon hardly distinguishes between the two concepts. Jewish religious practice, by definition, was observed exclusively by the Jewish people, and notions of Jewish peoplehood, nation, and community were suffused with faith in the Jewish God, the practice of Jewish (religious) la ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
People From Giraltovce
A person ( : people) is a being that has certain capacities or attributes such as reason, morality, consciousness or self-consciousness, and being a part of a culturally established form of social relations such as kinship, ownership of property, or legal responsibility. The defining features of personhood and, consequently, what makes a person count as a person, differ widely among cultures and contexts. In addition to the question of personhood, of what makes a being count as a person to begin with, there are further questions about personal identity and self: both about what makes any particular person that particular person instead of another, and about what makes a person at one time the same person as they were or will be at another time despite any intervening changes. The plural form "people" is often used to refer to an entire nation or ethnic group (as in "a people"), and this was the original meaning of the word; it subsequently acquired its use as a plural form of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Columbia University Vagelos College Of Physicians And Surgeons Alumni
Columbia may refer to: * Columbia (personification), the historical female national personification of the United States, and a poetic name for America Places North America Natural features * Columbia Plateau, a geologic and geographic region in the U.S. Pacific Northwest * Columbia River, in Canada and the United States ** Columbia Bar, a sandbar in the estuary of the Columbia River ** Columbia Country, the region of British Columbia encompassing the northern portion of that river's upper reaches *** Columbia Valley, a region within the Columbia Country ** Columbia Lake, a lake at the head of the Columbia River *** Columbia Wetlands, a protected area near Columbia Lake ** Columbia Slough, along the Columbia watercourse near Portland, Oregon * Glacial Lake Columbia, a proglacial lake in Washington state * Columbia Icefield, in the Canadian Rockies * Columbia Island (District of Columbia), in the Potomac River * Columbia Island (New York), in Long Island Sound Populated p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jewish American Scientists
Jews ( he, יְהוּדִים, , ) or Jewish people are an ethnoreligious group and nation originating from the Israelites Israelite origins and kingdom: "The first act in the long drama of Jewish history is the age of the Israelites""The people of the Kingdom of Israel and the ethnic and religious group known as the Jewish people that descended from them have been subjected to a number of forced migrations in their history" and Hebrews of historical Israel and Judah. Jewish ethnicity, nationhood, and religion are strongly interrelated, "Historically, the religious and ethnic dimensions of Jewish identity have been closely interwoven. In fact, so closely bound are they, that the traditional Jewish lexicon hardly distinguishes between the two concepts. Jewish religious practice, by definition, was observed exclusively by the Jewish people, and notions of Jewish peoplehood, nation, and community were suffused with faith in the Jewish God, the practice of Jewish (religious) l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Hematologists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * Ba ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1964 Deaths
Events January * January 1 – The Federation of Rhodesia and Nyasaland is dissolved. * January 5 - In the first meeting between leaders of the Roman Catholic and Orthodox churches since the fifteenth century, Pope Paul VI and Patriarch Athenagoras I of Constantinople meet in Jerusalem. * January 6 – A British firm, the Leyland Motor Corp., announces the sale of 450 buses to the Cuban government, challenging the United States blockade of Cuba. * January 9 – '' Martyrs' Day'': Armed clashes between United States troops and Panamanian civilians in the Panama Canal Zone precipitate a major international crisis, resulting in the deaths of 21 Panamanians and 4 U.S. soldiers. * January 11 – United States Surgeon General Luther Terry reports that smoking may be hazardous to one's health (the first such statement from the U.S. government). * January 12 ** Zanzibar Revolution: The predominantly Arab government of Zanzibar is overthrown by African nationalist rebels ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1879 Births
Events January–March * January 1 – The Specie Resumption Act takes effect. The United States Note is valued the same as gold, for the first time since the American Civil War. * January 11 – The Anglo-Zulu War begins. * January 22 – Anglo-Zulu War – Battle of Isandlwana: A force of 1,200 British soldiers is wiped out by over 20,000 Zulu warriors. * January 23 – Anglo-Zulu War – Battle of Rorke's Drift: Following the previous day's defeat, a smaller British force of 140 successfully repels an attack by 4,000 Zulus. * February 3 – Mosley Street in Newcastle upon Tyne (England) becomes the world's first public highway to be lit by the electric incandescent light bulb invented by Joseph Swan. * February 8 – At a meeting of the Royal Canadian Institute, engineer and inventor Sandford Fleming first proposes the global adoption of standard time. * March 3 – United States Geological Survey is founded. * March ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
John Vivian Dacie
Sir John Vivian Dacie, FRS (20 July 1912 Putney, London – 12 February 2005) was a British haematologist. Education He was born in Putney, London and educated at King's College School, Wimbledon, after which he studied medicine at King's College Hospital Medical School, qualifying in 1936. Career He had house jobs at King's College Hospital, the Royal Postgraduate Medical School, London University, Hammersmith and a research post at Manchester Royal Infirmary. During World War II (1943–1946) he served in the Royal Army Medical Corps, ending up a lieutenant colonel. After the war he was a Senior Lecturer and then in 1956 Professor at the Royal Postgraduate Medical School. He founded the Leukaemia Research Fund, Great Ormond Street, London (1960). His main achievements concerned the Hemolytic anemias, a field in which he was a world leader. He discovered and named Christmas disease, more commonly referred to as haemophilia B, a deficiency of coagulation Factor IX. Sir Dac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ADAMTS13
ADAMTS13 (''a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13'')—also known as ''von Willebrand factor-cleaving protease'' (VWFCP)—is a zinc-containing metalloprotease enzyme that cleaves von Willebrand factor (vWf), a large protein involved in blood clotting. It is secreted into the blood and degrades large vWf multimers, decreasing their activity. Genetics The ''ADAMTS13'' gene maps to the ninth chromosome (9q34). Discovery Since 1982 it had been known that thrombotic thrombocytopenic purpura (TTP), one of the microangiopathic hemolytic anemias (see below), was characterized in its familial form by the presence in plasma of unusually large von Willebrand factor multimers (ULVWF). In 1994, vWF was shown to be cleaved between a tyrosine at position 1605 and a methionine at 1606 by a plasma metalloprotease enzyme when it was exposed to high levels of shear stress. In 1996, two research groups independently further characterized this enzym ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thrombotic Thrombocytopenic Purpura
Thrombotic thrombocytopenic purpura (TTP) is a blood disorder that results in blood clots forming in small blood vessels throughout the body. This results in a low platelet count, low red blood cells due to their breakdown, and often kidney, heart, and brain dysfunction. Symptoms may include large bruises, fever, weakness, shortness of breath, confusion, and headache. Repeated episodes may occur. In about half of cases a trigger is identified, while in the remainder the cause remains unknown. Known triggers include bacterial infections, certain medications, autoimmune diseases such as lupus, and pregnancy. The underlying mechanism typically involves antibodies inhibiting the enzyme ADAMTS13. This results in decreased break down of large multimers of von Willebrand factor (vWF) into smaller units. Less commonly TTP is inherited from a person's parents, known as Upshaw–Schulman syndrome, such that ADAMTS13 dysfunction is present from birth. Diagnosis is typically based on ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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