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Electrocochleography
Electrocochleography (abbreviated ECochG or ECOG) is a technique of recording electrical potentials generated in the inner ear and auditory nerve in response to sound stimulation, using an electrode placed in the ear canal or tympanic membrane. The test is performed by an otologist or audiologist with specialized training, and is used for detection of elevated inner ear pressure ( endolymphatic hydrops) or for the testing and monitoring of inner ear and auditory nerve function during surgery. Clinical applications The most common clinical applications of electrocochleography include: * Objective identification and monitoring of Ménière's disease and endolymphatic hydrops (EH) * Intraoperative monitoring of auditory system function during surgery on the brainstem or cerebellum * Enhancement of Wave I of the auditory brainstem response, particularly in patients who are hard of hearing * Diagnosis of auditory neuropathy Cochlear physiology The basilar membrane and the h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electrocorticography
Electrocorticography (ECoG), a type of intracranial electroencephalography (iEEG), is a type of electrophysiological monitoring that uses electrodes placed directly on the exposed surface of the brain to record electrical activity from the cerebral cortex. In contrast, conventional electroencephalography (EEG) electrodes monitor this activity from outside the skull. ECoG may be performed either in the operating room during surgery (intraoperative ECoG) or outside of surgery (extraoperative ECoG). Because a craniotomy (a surgical incision into the skull) is required to implant the electrode grid, ECoG is an invasive procedure. History ECoG was pioneered in the early 1950s by Wilder Penfield and Herbert Jasper, neurosurgeons at the Montreal Neurological Institute. The two developed ECoG as part of their groundbreakinMontreal procedure a surgical protocol used to treat patients with severe epilepsy. The cortical potentials recorded by ECoG were used to identify epileptogen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oval Window
The oval window (or ''fenestra vestibuli'' or ''fenestra ovalis'') is a connective tissue membrane-covered opening from the middle ear to the cochlea of the inner ear. Vibrations that contact the tympanic membrane travel through the three ossicles and into the inner ear. The oval window is the intersection of the middle ear with the inner ear and is directly contacted by the stapes; by the time vibrations reach the oval window, they have been reduced in amplitude and increased in pressure due to the lever action of the ossicle bones. This is not an amplification function; rather, an impedance-matching function, allowing sound to be transferred from air (outer ear) to liquid (cochlea). It is a reniform (kidney-shaped) opening leading from the tympanic cavity into the vestibule of the inner ear; its long diameter is horizontal and its convex border is upward. It is occupied by the base of the ''stapes'', the circumference of which is fixed by the annular ligament to the margin of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Charles Bray
Charles Bray (31 January 1811 – 5 October 1884) was a prosperous British ribbon manufacturer, social reformer, philanthropist, philosopher, and phrenologist. Life Bray was born in 1811 and his education included time in the school run by Mary Franklin. He would have attended chapel every day. Bray became a prosperous ribbon manufacturer who owned the '' Coventry Herald'' newspaper. His father had died in 1835, leaving him and each of his seven siblings a substantial inheritance. Charles married Caroline "Cara" Hennell (4 June 1814 – 21 February 1905) on 26 May 1836 at Hackney in Middlesex. A disciple of the social reformer Robert Owen, he used the wealth generated from his businesses to establish nonsectarian public schools and to try to bring about changes in society. Bray was a pantheist who argued that God cannot be separated from nature.Postlethwaite, Diana. (1984). ''Making it Whole: A Victorian Circle and the Shape of Their World''. Ohio State University Pres ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ernest Wever
Ernest is a given name derived from the Germanic word ''ernst'', meaning "serious", often shortened to Ernie. Notable people and fictional characters with the name include: People *Archduke Ernest of Austria (1553–1595), son of Maximilian II, Holy Roman Emperor *Ernest, Margrave of Austria (1027–1075) *Ernest, Duke of Bavaria (1373–1438) *Ernest, Duke of Opava (c. 1415–1464) *Ernest, Margrave of Baden-Durlach (1482–1553) *Ernest, Landgrave of Hesse-Rheinfels (1623–1693) *Ernest Augustus, Elector of Brunswick-Lüneburg (1629–1698) *Ernest, Count of Stolberg-Ilsenburg (1650–1710) *Ernest Augustus, King of Hanover (1771–1851), son of King George III of Great Britain *Ernest II, Duke of Saxe-Coburg and Gotha (1818–1893), sovereign duke of the Duchy of Saxe-Coburg and Gotha *Ernest Augustus, Crown Prince of Hanover (1845–1923) *Ernest, Landgrave of Hesse-Philippsthal (1846–1925) *Ernest Augustus, Prince of Hanover (1914–1987) *Prince Ernst August of Hano ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Direct Current
Direct current (DC) is one-directional electric current, flow of electric charge. An electrochemical cell is a prime example of DC power. Direct current may flow through a conductor (material), conductor such as a wire, but can also flow through semiconductors, electrical insulation, insulators, or even through a vacuum as in electron beam, electron or ion beams. The electric current flows in a constant direction, distinguishing it from alternating current (AC). A archaism, term formerly used for this type of current was galvanic current. The abbreviations ''AC'' and ''DC'' are often used to mean simply ''alternating'' and ''direct'', as when they modify ''Electric current, current'' or ''voltage''. Direct current may be converted from an alternating current supply by use of a rectifier, which contains Electronics, electronic elements (usually) or electromechanical elements (historically) that allow current to flow only in one direction. Direct current may be converted into alt ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Frequency Following Response
The frequency following response (FFR), also referred to as frequency following potential (FFP) is an evoked potential generated by periodic or nearly-periodic auditory stimuli.Burkard, R., Don, M., & Eggermont, J. J. Auditory evoked potentials: Basic principles and clinical application. Philadelphia: Lippincott Williams & Wilkins. Part of the auditory brainstem response (ABR), the FFR reflects sustained neural activity integrated over a population of neural elements: "the brainstem response...can be divided into transient and sustained portions, namely the onset response and the frequency-following response (FFR)". It is often phase-locked to the individual cycles of the stimulus waveform and/or the envelope of the periodic stimuli. It has not been well studied with respect to its clinical utility, although it can be used as part of a test battery for helping to diagnose auditory neuropathy. This may be in conjunction with, or as a replacement for, otoacoustic emissions. History ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alternating Current
Alternating current (AC) is an electric current that periodically reverses direction and changes its magnitude continuously with time, in contrast to direct current (DC), which flows only in one direction. Alternating current is the form in which electric power is delivered to businesses and residences, and it is the form of electrical energy that consumers typically use when they plug kitchen appliances, televisions, Fan (machine), fans and electric lamps into a wall socket. The abbreviations ''AC'' and ''DC'' are often used to mean simply ''alternating'' and ''direct'', respectively, as when they modify ''Electric current, current'' or ''voltage''. The usual waveform of alternating current in most electric power circuits is a sine wave, whose positive half-period corresponds with positive direction of the current and vice versa (the full period is called a ''wave cycle, cycle''). "Alternating current" most commonly refers to power distribution, but a wide range of other appl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Action Potential
An action potential (also known as a nerve impulse or "spike" when in a neuron) is a series of quick changes in voltage across a cell membrane. An action potential occurs when the membrane potential of a specific Cell (biology), cell rapidly rises and falls. This depolarization then causes adjacent locations to similarly depolarize. Action potentials occur in several types of Membrane potential#Cell excitability, excitable cells, which include animal cells like neurons and myocyte, muscle cells, as well as some plant cells. Certain endocrine cells such as pancreatic beta cells, and certain cells of the anterior pituitary gland are also excitable cells. In neurons, action potentials play a central role in cell–cell interaction, cell–cell communication by providing for—or with regard to saltatory conduction, assisting—the propagation of signals along the neuron's axon toward axon terminal, synaptic boutons situated at the ends of an axon; these signals can then connect wit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Postsynaptic Potential
Postsynaptic potentials are changes in the membrane potential of the postsynaptic terminal of a chemical synapse. Postsynaptic potentials are graded potentials, and should not be confused with action potentials although their function is to initiate or inhibit action potentials. Postsynaptic potentials occur when the presynaptic neuron releases neurotransmitters into the synaptic cleft. These neurotransmitters bind to receptors on the postsynaptic terminal, which may be a neuron, or a muscle cell in the case of a neuromuscular junction. These are collectively referred to as postsynaptic receptors, since they are located on the membrane of the postsynaptic cell. Postsynaptic potentials are important mechanisms by which neurons communicate with each other allowing for information processing, learning, memory formation, and complex behavior within the nervous system. Ion Involvement Ions can create excitatory or inhibitory potentials due to their unique reversal potentials and the m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spiral Ganglion
The spiral (cochlear) ganglion is a group of neuron cell bodies in the modiolus, the conical central axis of the cochlea. These bipolar neurons innervate the hair cells of the organ of Corti. They project their axons to the ventral and dorsal cochlear nuclei as the cochlear nerve, a branch of the vestibulocochlear nerve (CN VIII). Structure Neurons whose cell bodies lie in the spiral ganglion are strung along the bony core of the cochlea, and send fibers (axons) into the central nervous system (CNS). These bipolar neurons are the first neurons in the auditory system to fire an action potential, and supply all of the brain's auditory input. Their dendrites make synaptic contact with the base of hair cells, and their axons are bundled together to form the auditory portion of eighth cranial nerve. The number of neurons in the spiral ganglion is estimated to be about 35,000–50,000. Two apparent subtypes of spiral ganglion cells exist. Type I spiral ganglion cells com ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adenosine Triphosphate
Adenosine triphosphate (ATP) is a nucleoside triphosphate that provides energy to drive and support many processes in living cell (biology), cells, such as muscle contraction, nerve impulse propagation, and chemical synthesis. Found in all known forms of life, it is often referred to as the "molecular unit of currency" for intracellular energy transfer. When consumed in a Metabolism, metabolic process, ATP converts either to adenosine diphosphate (ADP) or to adenosine monophosphate (AMP). Other processes regenerate ATP. It is also a Precursor (chemistry), precursor to DNA and RNA, and is used as a coenzyme. An average adult human processes around 50 kilograms (about 100 mole (unit), moles) daily. From the perspective of biochemistry, ATP is classified as a nucleoside triphosphate, which indicates that it consists of three components: a nitrogenous base (adenine), the sugar ribose, and the Polyphosphate, triphosphate. Structure ATP consists of three parts: a sugar, an amine base ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stereocilia
Stereocilia (or stereovilli or villi) are non-motile apical cell modifications. They are distinct from cilia and microvilli, but are closely related to microvilli. They form single "finger-like" projections that may be branched, with normal cell membrane characteristics. They contain actin. Stereocilia are found in the vas deferens, the epididymis, and the sensory cells of the inner ear. Structure Stereocilia are cylindrical and non-motile. They are much longer and thicker than microvilli, form single "finger-like" projections that may be branched, and have more of the characteristics of the cellular membrane proper. Like microvilli, they contain actin and lack an axoneme. This distinguishes them from cilia. They do not have a basal body at their base since they do not contain microtubules. They may or may not be covered by a glycocalyx coating. They have no fixed arrangement, different to the structure present in kinocilium. Organs containing stereocilia Stereocilia are ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
