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Diclofenac Sodium
Diclofenac, sold under the brand name Voltaren, among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammatory diseases such as gout. It is taken by mouth or rectally in a suppository, used by injection, or applied to the skin. Improvements in pain last for as much as eight hours. It is also available in combination with misoprostol in an effort to decrease stomach problems. Common side effects include abdominal pain, gastrointestinal bleeding, nausea, dizziness, headache, and swelling. Serious side effects may include heart disease, stroke, kidney problems, and stomach ulceration. Use is not recommended in the third trimester of pregnancy. It is likely safe during breastfeeding. Diclofenac is believed to work by decreasing the production of prostaglandins, like other drugs in this class. Diclofenac was patented in 1965 by J.R. Geigy AG; it came into medical use in the United States in 1988. It is available as a generic medication. In 2 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diclofenac/misoprostol
Diclofenac/misoprostol, sold under the brand name Arthrotec, is a fixed-dose combination medication that contains: *Diclofenac sodium: Nonsteroidal anti-inflammatory drug (NSAID) with analgesic properties *Misoprostol: Gastrointestinal (GI) mucosal protective prostaglandin E1 analog. In the United Kingdom it is marketed by Pharmacia and it is indicated for prophylaxis against NSAID-induced gastroduodenal ulceration in people requiring diclofenac for rheumatoid arthritis or osteoarthritis. The American College of Rheumatology and a Canadian consensus report both recommend GI-protective agents such as misoprostol be combined with long term NSAID therapy and a review concluded that diclofenac/misoprostol is a cost effective treatment in patients requiring long term NSAID therapy who are at increased risk of developing gastropathy. Contraindications Arthrotec must not be taken during pregnancy, as it may deform or otherwise harm the fetus A fetus or foetus (; plural fetuses ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |