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Dendral
Dendral was a project in artificial intelligence (AI) of the 1960s, and the computer software expert system that it produced. Its primary aim was to study hypothesis formation and discovery in science. For that, a specific task in science was chosen: help organic chemists in identifying unknown organic molecules, by analyzing their mass spectra and using knowledge of chemistry.November, 2006 It was done at Stanford University by Edward Feigenbaum, Bruce G. Buchanan, Joshua Lederberg, and Carl Djerassi, along with a team of highly creative research associates and students. It began in 1965 and spans approximately half the history of AI research.Lindsay et al., 1980 The software program Dendral is considered the first expert system because it automated the decision-making process and problem-solving behavior of organic chemists. The project consisted of research on two main programs Heuristic Dendral and Meta-Dendral, and several sub-programs. It was written in the Lisp program ...
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Expert System
In artificial intelligence, an expert system is a computer system emulating the decision-making ability of a human expert. Expert systems are designed to solve complex problems by reasoning through bodies of knowledge, represented mainly as if–then rules rather than through conventional procedural code. The first expert systems were created in the 1970s and then proliferated in the 1980s. Expert systems were among the first truly successful forms of artificial intelligence (AI) software. An expert system is divided into two subsystems: the inference engine and the knowledge base. The knowledge base represents facts and rules. The inference engine applies the rules to the known facts to deduce new facts. Inference engines can also include explanation and debugging abilities. History Early development Soon after the dawn of modern computers in the late 1940s and early 1950s, researchers started realizing the immense potential these machines had for modern society. One ...
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History Of Artificial Intelligence
The history of artificial intelligence (AI) began in ancient history, antiquity, with myths, stories and rumors of artificial beings endowed with intelligence or consciousness by master craftsmen. The seeds of modern AI were planted by philosophers who attempted to describe the process of human thinking as the mechanical manipulation of symbols.This work culminated in the invention of the computer, programmable digital computer in the 1940s, a machine based on the abstract essence of mathematical reasoning. This device and the ideas behind it inspired a handful of scientists to begin seriously discussing the possibility of building an electronic brain. The field of artificial intelligence, AI research was founded at a Dartmouth workshop, workshop held on the campus of Dartmouth College, USA during the summer of 1956. Those who attended would become the leaders of AI research for decades. Many of them predicted that a machine as intelligent as a human being would exist in no mor ...
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Edward Feigenbaum
Edward Albert Feigenbaum (born January 20, 1936) is a computer scientist working in the field of artificial intelligence, and joint winner of the 1994 ACM Turing Award. He is often called the "father of expert systems." Education and early life Feigenbaum was born in Weehawken, New Jersey in 1936 to a culturally Jewish family, and moved to nearby North Bergen, where he lived until the age of 16, when he left to start college. Knuth, Don"Oral History of Edward Feigenbaum'' Computer History Museum, 2007. Accessed October 23, 2015. "I was born in Weehawken, New Jersey, which is a town on the Palisades opposite New York. In fact, it’s the place where the Lincoln Tunnel dives under the water and comes up in New York. Then my parents moved up the Palisades four miles to a town called North Bergen, and there I lived until I was 16 and went off to Carnegie Tech." His hometown did not have a secondary school of its own, and so he chose Weehawken High School for its college preparatory p ...
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Carl Djerassi
Carl Djerassi (October 29, 1923 – January 30, 2015) was an Austrian-born Bulgarian-American pharmaceutical chemist, novelist, playwright and co-founder of Djerassi Resident Artists Program with Diane Wood Middlebrook. He is best known for his contribution to the development of oral contraceptive pills,Ball P (2015) "Carl Djerassi", Nature 519(7541), 34. nicknamed the "father of the pill". Early life Carl Djerassi was born in Vienna, Austria, but spent the first years of his infancy in Sofia, Bulgaria, the home of his father, Samuel Djerassi, a dermatologist and specialist in sexually transmitted diseases.Weintraub, Bob "Pincus, Djerassi and Oral Contraceptives" ''Chemistry in Israel'', Bulletin of the Israel Chemical Society. August 2005, pp. 47–50. His mother was Alice Friedmann, a Viennese dentist and physician. Both parents were Jewish. Following his parents' divorce, Djerassi and his mother moved to Vienna. Until the age of 14, he attended the same ''realgymnasium'' tha ...
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George Polya
George may refer to: People * George (given name) * George (surname) * George (singer), American-Canadian singer George Nozuka, known by the mononym George * George Washington, First President of the United States * George W. Bush, 43rd President of the United States * George H. W. Bush, 41st President of the United States * George V, King of Great Britain, Ireland, the British Dominions and Emperor of India from 1910-1936 * George VI, King of Great Britain, Ireland, the British Dominions and Emperor of India from 1936-1952 * Prince George of Wales * George Papagheorghe also known as Jorge / GEØRGE * George, stage name of Giorgio Moroder * George Harrison, an English musician and singer-songwriter Places South Africa * George, Western Cape ** George Airport United States * George, Iowa * George, Missouri * George, Washington * George County, Mississippi * George Air Force Base, a former U.S. Air Force base located in California Characters * George (Peppa Pig), a 2-year-o ...
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Herbert A
Herbert may refer to: People Individuals * Herbert (musician), a pseudonym of Matthew Herbert Name * Herbert (given name) * Herbert (surname) Places Antarctica * Herbert Mountains, Coats Land * Herbert Sound, Graham Land Australia * Herbert, Northern Territory, a rural locality * Herbert, South Australia. former government town * Division of Herbert, an electoral district in Queensland * Herbert River, a river in Queensland * County of Herbert, a cadastral unit in South Australia Canada * Herbert, Saskatchewan, Canada, a town * Herbert Road, St. Albert, Canada New Zealand * Herbert, New Zealand, a town * Mount Herbert (New Zealand) United States * Herbert, Illinois, an unincorporated community * Herbert, Michigan, a former settlement * Herbert Creek, a stream in South Dakota * Herbert Island, Alaska Arts, entertainment, and media Fictional entities * Herbert (Disney character) * Herbert Pocket (''Great Expectations'' character), Pip's close friend and roommate in t ...
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John McCarthy (computer Scientist)
John McCarthy (September 4, 1927 – October 24, 2011) was an American computer scientist and cognitive scientist. He was one of the founders of the discipline of artificial intelligence. He co-authored the document that coined the term "artificial intelligence" (AI), developed the programming language family Lisp (programming language), Lisp, significantly influenced the design of the language ALGOL, popularized time-sharing, and invented Garbage collection (computer science), garbage collection. McCarthy spent most of his career at Stanford University. He received many accolades and honors, such as the 1971 Turing Award for his contributions to the topic of AI, the United States National Medal of Science, and the Kyoto Prize. Early life and education John McCarthy was born in Boston, Massachusetts, on September 4, 1927, to an Irish people, Irish immigrant father and a Lithuanian Jewish immigrant mother, John Patrick and Ida (Glatt) McCarthy. The family was obliged to relocat ...
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Hemoglobin
Hemoglobin (haemoglobin BrE) (from the Greek word αἷμα, ''haîma'' 'blood' + Latin ''globus'' 'ball, sphere' + ''-in'') (), abbreviated Hb or Hgb, is the iron-containing oxygen-transport metalloprotein present in red blood cells (erythrocytes) of almost all vertebrates (the exception being the fish family Channichthyidae) as well as the tissues of some invertebrates. Hemoglobin in blood carries oxygen from the respiratory organs (''e.g.'' lungs or gills) to the rest of the body (''i.e.'' tissues). There it releases the oxygen to permit aerobic respiration to provide energy to power functions of an organism in the process called metabolism. A healthy individual human has 12to 20grams of hemoglobin in every 100mL of blood. In mammals, the chromoprotein makes up about 96% of the red blood cells' dry content (by weight), and around 35% of the total content (including water). Hemoglobin has an oxygen-binding capacity of 1.34mL O2 per gram, which increases the total blood oxy ...
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Exobiology
Astrobiology, and the related field of exobiology, is an interdisciplinary scientific field that studies the origins, early evolution, distribution, and future of life in the universe. Astrobiology is the multidisciplinary field that investigates the deterministic conditions and contingent events with which life arises, distributes, and evolves in the universe. Astrobiology makes use of molecular biology, biophysics, biochemistry, chemistry, astronomy, physical cosmology, exoplanetology, geology, paleontology, and ichnology to investigate the possibility of life on other worlds and help recognize biospheres that might be different from that on Earth. The origin and early evolution of life is an inseparable part of the discipline of astrobiology. Astrobiology concerns itself with interpretation of existing scientific data, and although speculation is entertained to give context, astrobiology concerns itself primarily with hypotheses that fit firmly into existing scientific th ...
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Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid ...
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Chemical Graph
In chemical graph theory and in mathematical chemistry, a molecular graph or chemical graph is a representation of the structural formula of a chemical compound in terms of graph theory. A chemical graph is a labeled graph whose vertices correspond to the atoms of the compound and edges correspond to chemical bonds. Its vertices are labeled with the kinds of the corresponding atoms and edges are labeled with the types of bonds. For particular purposes any of the labelings may be ignored. A hydrogen-depleted molecular graph or hydrogen-suppressed molecular graph is the molecular graph with hydrogen vertices deleted. In some important cases (topological index calculation etc.) the following classical definition is sufficient: a molecular graph is a connected, undirected graph which admits a one-to-one correspondence with the structural formula of a chemical compound in which the vertices of the graph correspond to atoms of the molecule and edges of the graph correspond to chemica ...
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