|
Circovirus
''Circovirus'' is a genus of viruses, in the family ''Circoviridae''. Birds (such as pigeons and ducks) and pigs serve as natural hosts, though dogs have been shown to be infected as well. It is a single stranded DNA virus (ssDNA). There are 49 species in this genus. Some members of this genus cause disease: PCV-1 is non pathogenic, while PCV-2 causes postweaning multisystemic wasting syndrome (PMWS). Taxonomy The following species are recognized: *'' Barbel circovirus'' *'' Bat associated circovirus 1'' *'' Bat associated circovirus 2'' *'' Bat associated circovirus 3'' *'' Bat associated circovirus 4'' *'' Bat associated circovirus 5'' *'' Bat associated circovirus 6'' *'' Bat associated circovirus 7'' *'' Bat associated circovirus 8'' *'' Bat associated circovirus 9'' *'' Bat associated circovirus 10'' *'' Bat associated circovirus 11'' *'' Bat associated circovirus 12'' *'' Bat associated circovirus 13'' *'' Beak and feather disease virus'' *'' Bear circovirus'' *'' Canary ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Canine Circovirus
''Canine circovirus'' (CaCV or DogCV), first isolated in 2012, is a small non-enveloped, icosahedral, single-stranded DNA virus that infects domestic dogs and wild canids exclusively. It is a member of the ''Circoviridae'' family and the genus ''Circovirus''. There are currently 11 species of known circoviruses that have been identified to affect a wide variety of birds and mammals. As seen with all extensively studied circoviruses, the diameter ranges between approximately 15 and 25 nanometers. The icosahedral triangulation number is 1, the smallest size a viral capsid can be, in which there are a total of 60 protein subunits that make up the capsid. CaCV is not to be confused with canine coronavirus, another diarrhea-causing agent within the family ''Coronaviridae'', or porcine circoviruses which are a members of the same genus as CaCV but only seen in pigs. CaCV (genome 1) was the first ''Circovirus'' to be identified that infects a mammal species other than pigs. Genome The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Circoviridae
''Circoviridae'' is a family of DNA viruses. Birds and mammals serve as natural hosts. There are 101 species in this family, assigned to 2 genera. Diseases associated with this family include: PCV-2: postweaning multisystemic wasting syndrome; CAV: chicken infectious anemia. Structure Viruses in the family ''Circoviridae'' are non-enveloped, with icosahedral and round geometries, and T=1 symmetry. The diameter is around 20 nm. Genomes are circular and non-segmented, around 3.8kb in length. The capsid consists of 12 pentagonal trumpet-shaped pentamers. There are two main open reading frames arranged in opposite directions that encode the replication and capsid proteins. Alternative start codons are common in the avian species. Life cycle Viral replication is nuclear. Entry into the host cell is achieved by penetration into the host cell. Replication follows the ssDNA rolling circle model. DNA templated transcription, with some alternative splicing mechanism is the method ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Duck Circovirus
''Duck circovirus'' (DuCV) is a type of virus found in ducks. Strains of the virus have predominantly been found in China, though strains have also been isolated from ducks in Germany and the United States. ''Duck circovirus'' is a small nonenveloped virus with a monomeric single-stranded circular DNA genome. DuCV has been clustered in the ''Circoviridae'' family genus ''Circovirus'', according to the eighth report of the International Committee on Taxonomy of Viruses. Pathogenicity Scientists have studied ''Duck circovirus'' by using polymerase chain reaction (PCR)-based methods and dot blot hybridisation (DBH) tests. Infection with DuCV appears to cause growth disorders in ducks as well as eventual immunosuppression due to depletion of lymphatic cells. Transmission It was found that ducks between the ages of 40~60 days were more susceptible to ''Duck circovirus''. There was no evidence showing that the DuCV virus was capable of vertical transmission. Clinical signs The clin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Postweaning Multisystemic Wasting Syndrome
Porcine circoviral disease (PCVD) and porcine circovirus associated disease (PCVAD), is a disease seen in domestic pigs. This disease causes illness in piglets, with clinical signs including progressive loss of body condition, visibly enlarged lymph nodes, difficulty in breathing, and sometimes diarrhea, pale skin, and jaundice. PCVD is very damaging to the pig-producing industry and has been reported worldwide. PCVD is caused by ''Porcine circovirus 2'' (PCV-2). The North American industry endorses "PCVAD" and European use "PCVD" to describe this disease. PMWS and PCV-2 ''Postweaning multisystemic wasting syndrome'' (''PMWS'') is the classic PCVD entity, caused by PCV-2. PCV-2 has a near universal distribution – present in most pig herds. In contrast, PMWS is more sporadic in its distribution. Experimental induction of PMWS has not been achieved by PCV-2 infection alone, using infectious DNA clones of the virus or a pure form of PCV-2 derived from infectious DNA clones. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Beak And Feather Disease Virus
Psittacine beak and feather disease (PBFD) is a viral disease affecting all Old World and New World parrots. The causative virus—''beak and feather disease virus'' (BFDV)—belongs to the taxonomic genus ''Circovirus'', family ''Circoviridae''. It attacks the feather follicles and the beak and claw matrices of the bird, causing progressive feather, claw and beak malformation and necrosis. In later stages of the disease, feather shaft constriction occurs, hampering development until eventually all feather growth stops. It occurs in an acutely fatal form and a chronic form. Cracking and peeling of the outer layers of the claws and beak make tissues vulnerable to secondary infection. Because the virus also affects the thymus and Bursa of Fabricius, slowing lymphocyte production, immunosuppression occurs and the bird becomes more vulnerable to secondary infections. Beak fractures and necrosis of the hard palate can prevent the bird from eating.Pyne, MPsittacine Beak and Feather ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bear Circovirus
Bears are carnivoran mammals of the family Ursidae. They are classified as caniforms, or doglike carnivorans. Although only eight species of bears are extant, they are widespread, appearing in a wide variety of habitats throughout the Northern Hemisphere and partially in the Southern Hemisphere. Bears are found on the continents of North America, South America, Europe, and Asia. Common characteristics of modern bears include large bodies with stocky legs, long snouts, small rounded ears, shaggy hair, plantigrade paws with five nonretractile claws, and short tails. While the polar bear is mostly carnivorous, and the giant panda feeds almost entirely on bamboo, the remaining six species are omnivorous with varied diets. With the exception of courting individuals and mothers with their young, bears are typically solitary animals. They may be diurnal or nocturnal and have an excellent sense of smell. Despite their heavy build and awkward gait, they are adept runners, cli ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
