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Gamaleya Research Institute Of Epidemiology And Microbiology
The Gamaleya Research Institute of Epidemiology and Microbiology, previously the N. F. Gamaleya Federal Research Center for Epidemiology & Microbiology, is a Russian medical-research institute within the Ministry of Health of the Russian Federation.Other names include the Gamaleya Scientific Research Institute or Gamaleya National Research Center for Epidemiology and Microbiology Founded in 1891 by Filipp Markovich Blyumental, it is named after Soviet scientist Nikolay Fyodorovich Gamaleya (1859–1949), famed as a pioneer in microbiology and in vaccine research. The institute is best known internationally for developing the earliest vaccine for SARS-CoV-2, in collaboration with the 48th Central Research Institute of the Ministry of Defence and the Vector Institute of the Rospotrebnadzor, in response to the COVID-19 pandemic. History The institution was founded in 1891 as a private bacteriology- and chemical-microscopy-oriented laboratory, which later became the Blumenth ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Moscow
Moscow is the Capital city, capital and List of cities and towns in Russia by population, largest city of Russia, standing on the Moskva (river), Moskva River in Central Russia. It has a population estimated at over 13 million residents within the city limits, over 19.1 million residents in the urban area, and over 21.5 million residents in Moscow metropolitan area, its metropolitan area. The city covers an area of , while the urban area covers , and the metropolitan area covers over . Moscow is among the world's List of largest cities, largest cities, being the List of European cities by population within city limits, most populous city entirely in Europe, the largest List of urban areas in Europe, urban and List of metropolitan areas in Europe, metropolitan area in Europe, and the largest city by land area on the European continent. First documented in 1147, Moscow became the capital of the Grand Principality of Moscow, which led the unification of the Russian lan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Xinhua News Agency
Xinhua News Agency (English pronunciation: ),J. C. Wells: Longman Pronunciation Dictionary, 3rd ed., for both British and American English or New China News Agency, is the official state news agency of the People's Republic of China. It is a ministry-level institution of the State Council. Founded in 1931, it is the largest media organ in China. Xinhua is a publisher, as well as a news agency; it publishes in multiple languages and is a channel for the distribution of information related to the Chinese government and the ruling Chinese Communist Party (CCP). Its headquarters in Beijing are located close to the central government's headquarters at Zhongnanhai. Xinhua tailors its pro-Chinese government message to the nuances of each international audience. The organization has faced criticism for spreading propaganda and disinformation and for criticizing people, groups, or movements critical of the Chinese government and its policies. History The predecessor to Xinhua ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Organizations Based In Moscow
An organization or organisation (Commonwealth English; see spelling differences) is an entity—such as a company, or corporation or an institution (formal organization), or an association—comprising one or more people and having a particular purpose. Organizations may also operate secretly or illegally in the case of secret societies, criminal organizations, and resistance movements. And in some cases may have obstacles from other organizations (e.g.: MLK's organization). What makes an organization recognized by the government is either filling out incorporation or recognition in the form of either societal pressure (e.g.: Advocacy group), causing concerns (e.g.: Resistance movement) or being considered the spokesperson of a group of people subject to negotiation (e.g.: the Polisario Front being recognized as the sole representative of the Sahrawi people and forming a partially recognized state.) Compare the concept of social groups, which may include non-organiza ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Epidemics
An epidemic (from Ancient Greek, Greek ἐπί ''epi'' "upon or above" and δῆμος ''demos'' "people") is the rapid spread of disease to a large number of Host (biology), hosts in a given population within a short period of time. For example, in meningococcal infections, an attack rate in excess of 15 cases per 100,000 people for two consecutive weeks is considered an epidemic. Epidemics of infectious disease are generally caused by several factors including a change in the ecology of the host population (e.g., increased stress or increase in the density of a vector species), a genetic change in the pathogen reservoir or the introduction of an emerging pathogen to a host population (by movement of pathogen or host). Generally, an epidemic occurs when host Immunity (medicine), immunity to either an established pathogen or newly emerging novel pathogen is suddenly reduced below that found in the Endemic (epidemiology), endemic equilibrium and the transmission threshold is excee ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Infectious Disease Organizations
infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable disease, is an illness resulting from an infection. Infections can be caused by a wide range of pathogens, most prominently bacteria and viruses. Hosts can fight infections using their immune systems. Mammalian hosts react to infections with an innate response, often involving inflammation, followed by an adaptive response. Treatment for infections depends on the type of pathogen involved. Common medications include: * Antibiotics for bacterial infections. * Antivirals for viral infections. * Antifungals for fungal infections. * Antiprotozoals for protozoan infections. * Antihelminthics for infections caused by parasitic worms. Infectious diseases remain a significant global health concern, causing approximately 9.2 million deaths in 20 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gamaleya Research Institute Of Epidemiology And Microbiology
The Gamaleya Research Institute of Epidemiology and Microbiology, previously the N. F. Gamaleya Federal Research Center for Epidemiology & Microbiology, is a Russian medical-research institute within the Ministry of Health of the Russian Federation.Other names include the Gamaleya Scientific Research Institute or Gamaleya National Research Center for Epidemiology and Microbiology Founded in 1891 by Filipp Markovich Blyumental, it is named after Soviet scientist Nikolay Fyodorovich Gamaleya (1859–1949), famed as a pioneer in microbiology and in vaccine research. The institute is best known internationally for developing the earliest vaccine for SARS-CoV-2, in collaboration with the 48th Central Research Institute of the Ministry of Defence and the Vector Institute of the Rospotrebnadzor, in response to the COVID-19 pandemic. History The institution was founded in 1891 as a private bacteriology- and chemical-microscopy-oriented laboratory, which later became the Blumenth ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Immune Response
An immune response is a physiological reaction which occurs within an organism in the context of inflammation for the purpose of defending against exogenous factors. These include a wide variety of different toxins, viruses, intra- and extracellular bacteria, protozoa, Parasitic worm, helminths, and Fungus, fungi which could cause serious problems to the health of the host organism if not cleared from the body. In addition, there are other forms of immune response. For example, harmless exogenous factors (such as pollen and food components) can trigger allergy; latex and metals are also known allergens. A transplanted tissue (for example, blood) or organ can cause graft-versus-host disease. A type of immune reactivity known as Rh disease can be observed in pregnant women. These special forms of immune response are classified as hypersensitivity. Another special form of immune response is CD4+ T cells and antitumor immunity, antitumor immunity. In general, there are two branches of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biomarker
In biomedical contexts, a biomarker, or biological marker, is a measurable indicator of some biological state or condition. Biomarkers are often measured and evaluated using blood, urine, or soft tissues to examine normal biological processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention. as cited in Biomarkers are used in many scientific fields. Medicine Biomarkers used in the medical field, are a part of a relatively new clinical toolset categorized by their clinical applications. The four main classes are molecular, physiologic, histologic and radiographic biomarkers. All four types of biomarkers have a clinical role in narrowing or guiding treatment decisions and follow a sub-categorization of being either predictive, prognostic, or diagnostic. Predictive Predictive molecular, cellular, or imaging biomarkers that pass validation can serve as a method of predicting clinical outcomes. Predictive biomarkers are used to help optimize ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Effective Dose (pharmacology)
In pharmacology, an effective dose (ED) or effective concentration (EC) is the dose or concentration of a drug that produces a biological response. The term "effective dose" is used when measurements are taken ''in vivo,'' while "effective concentration" is used when the measurements are taken ''in vitro''. It has been stated that any substance can be toxic at a high enough dose. This concept was demonstrated in 2007 when a California woman died of water intoxication in a contest sanctioned by a radio station. The line between efficacy and toxicity is dependent upon the particular patient, although the dose administered by a physician should fall into the predetermined therapeutic window of the drug. The importance of determining the therapeutic range of a drug cannot be overstated. This is generally defined by the range between the minimum effective dose (MED) and the maximum tolerated dose (MTD). The MED is defined as the lowest dose level of a pharmaceutical product that ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clinical Trial
Clinical trials are prospective biomedical or behavioral research studies on human subject research, human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, pharmaceutical drug, drugs, medical nutrition therapy, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison. Clinical trials generate data on dosage, safety and efficacy. They are conducted only after they have received institutional review board, health authority/ethics committee approval in the country where approval of the therapy is sought. These authorities are responsible for vetting the risk/benefit ratio of the trial—their approval does not mean the therapy is 'safe' or effective, only that the trial may be conducted. Depending on product type and development stage, investigators initially enroll volunteers or patients into small Pilot experiment, pi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gam-COVID-Vac
Sputnik V (, the brand name from the Russian Direct Investment Fund or RDIF) or Gam-COVID-Vac (, the name under which it is legally registered and produced) is an adenovirus viral vector vaccine for COVID-19 developed by the Gamaleya Research Institute of Epidemiology and Microbiology in Russia. It is the world's first registered combination vector vaccine for the prevention of COVID-19, having been registered on 11 August 2020 by the Russian Ministry of Health. Gam-COVID-Vac was initially approved for distribution in Russia and then in 59 other countries (as of April 2021) on the preliminary results of Phase I– II studies eventually published on 4 September 2020. Approval in early August of Gam-COVID-Vac was met with criticism in mass media and discussions in the scientific community as to whether approval was justified in the absence of robust scientific research confirming safety and efficacy. A large-scale Brazilian study from Dec. 2020 to May 2021 confirmed its ef ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vladimir Putin
Vladimir Vladimirovich Putin (born 7 October 1952) is a Russian politician and former intelligence officer who has served as President of Russia since 2012, having previously served from 2000 to 2008. Putin also served as Prime Minister of Russia from 1999 to 2000 and again from 2008 to 2012. He is the longest-serving Russian president since the independence of Russia from the Soviet Union. Putin worked as a KGB foreign intelligence officer for 16 years, rising to the rank of Lieutenant colonel (Eastern Europe), lieutenant colonel. He resigned in 1991 to begin a political career in Saint Petersburg. In 1996, he moved to Moscow to join the administration of President Boris Yeltsin. He briefly served as the director of the Federal Security Service (FSB) and then as Secretary of the Security Council of Russia, secretary of the Security Council of Russia before Putin's rise to power, being appointed prime minister in August 1999. Following Yeltsin's resignation, Putin became Actin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
