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Core (laboratory)
A core facility (also known as core laboratory or simply "core", like in "flow cytometry core") is a centralized shared research resource that provides scientific community with access to unique and highly specialized instruments, technologies, services, and experts. Cores are frequently built around a specific technology or instrumentation, but not always (for example, biostatistics cores offer services of experts skilled in the use of software packages). A database of US core facilities is maintained by the Association of Biomolecular Resource Facilities. By the late 20th century, the researchers in the life sciences were increasingly dependent on the use of expensive and complex instruments and techniques that cannot be economically replicated inside each laboratory. In many areas (for example, in translational science) access to core laboratories became essential. Once the research institutions recognized the potential cost savings of provisioning state-of-the-art instrumentati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Flow Cytometry
Flow cytometry (FC) is a technique used to detect and measure the physical and chemical characteristics of a population of cells or particles. In this process, a sample containing cells or particles is suspended in a fluid and injected into the flow cytometer instrument. The sample is focused to ideally flow one cell at a time through a laser beam, where the light scattered is characteristic to the cells and their components. Cells are often labeled with fluorescent markers so light is absorbed and then emitted in a band of wavelengths. Tens of thousands of cells can be quickly examined and the data gathered are processed by a computer. Flow cytometry is routinely used in basic research, clinical practice, and clinical trials. Uses for flow cytometry include: * Cell counting * Cell sorting * Determining cell characteristics and function * Detecting microorganisms * Biomarker detection * Protein engineering detection * Diagnosis of health disorders such as blood cancers * Me ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
