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Comatose
A coma is a deep state of prolonged unconsciousness in which a person cannot be awakened, fails to respond normally to painful stimuli, light, or sound, lacks a normal sleep-wake cycle and does not initiate voluntary actions. The person may experience respiratory and circulatory problems due to the body's inability to maintain normal bodily functions. People in a coma often require extensive medical care to maintain their health and prevent complications such as pneumonia or blood clots. Coma patients exhibit a complete absence of wakefulness and are unable to consciously feel, speak or move. Comas can be the result of natural causes, or can be medically induced, for example, during general anesthesia. Clinically, a coma can be defined as the consistent inability to follow a one-step command. For a patient to maintain consciousness, the components of ''wakefulness'' and ''awareness'' must be maintained. Wakefulness is a quantitative assessment of the degree of consciousness, ...
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Persistent Vegetative State
A vegetative state (VS) or post-coma unresponsiveness (PCU) is a disorder of consciousness in which patients with severe brain damage are in a state of partial arousal rather than true awareness. After four weeks in a vegetative state, the patient is classified as being in a persistent vegetative state (PVS). This diagnosis is classified as a permanent vegetative state some months (three in the US and six in the UK) after a non-traumatic brain injury or one year after a traumatic injury. The term unresponsive wakefulness syndrome may be used alternatively, as "vegetative state" has some negative connotations among the public. It is occasionally also called Apallic syndrome or Apallisches syndrome, Loanword, borrowings from German, primarily in European or older sources. Definition There are several definitions that vary by technical versus layman's usage. There are different legal implications in different countries. Medical definition Per the definition of the British Royal ...
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Consciousness
Consciousness, at its simplest, is awareness of a state or object, either internal to oneself or in one's external environment. However, its nature has led to millennia of analyses, explanations, and debate among philosophers, scientists, and theologians. Opinions differ about what exactly needs to be studied or even considered consciousness. In some explanations, it is synonymous with the mind, and at other times, an aspect of it. In the past, it was one's "inner life", the world of introspection, of private thought, imagination, and volition (psychology), volition. Today, it often includes any kind of cognition, experience, feeling, or perception. It may be awareness, awareness of awareness, metacognition, or self-awareness, either continuously changing or not. The disparate range of research, notions, and speculations raises a curiosity about whether the right questions are being asked. Examples of the range of descriptions, definitions or explanations are: ordered distinc ...
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Neurology
Neurology (from , "string, nerve" and the suffix wikt:-logia, -logia, "study of") is the branch of specialty (medicine) , medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the nervous system, which comprises the Human brain, brain, the spinal cord and the peripheral nervous system , peripheral nerves. Neurological practice relies heavily on the field of neuroscience, the scientific study of the nervous system, using various techniques of neurotherapy. IEEE Brain (2019). "Neurotherapy: Treating Disorders by Retraining the Brain". ''The Future Neural Therapeutics White Paper''. Retrieved 23.01.2025 from: https://brain.ieee.org/topics/neurotherapy-treating-disorders-by-retraining-the-brain/#:~:text=Neurotherapy%20trains%20a%20patient's%20brain,wave%20activity%20through%20positive%20reinforcement International Neuromodulation Society, Retrieved 23 January 2025 from: https://www.neuromodulation.com/ Val Danilov I (2023). "The O ...
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Neuroscience
Neuroscience is the scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions, and its disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, developmental biology, cytology, psychology, physics, computer science, chemistry, medicine, statistics, and mathematical modeling to understand the fundamental and emergent properties of neurons, glia and neural circuits. The understanding of the biological basis of learning, memory, behavior, perception, and consciousness has been described by Eric Kandel as the "epic challenge" of the biological sciences. The scope of neuroscience has broadened over time to include different approaches used to study the nervous system at different scales. The techniques used by neuroscientists have expanded enormously, from molecular and cellular studies of individual neurons to imaging of sensory, motor and cognitive tasks in the brain. Hist ...
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Stimulation
Stimulation is the encouragement of development or the cause of activity in general. For example, "The press provides stimulation of political discourse." An interesting or fun activity can be described as "stimulating", regardless of its physical effects on senses. ''Stimulate'' means to act as a stimulus to; ''stimulus'' means something that rouses the recipient to activity; ''stimuli'' is the plural of ''stimulus''. A particular use of the term is physiological stimulation, which refers to sensory excitation, the action of various agents or forms of energy (Stimulus (physiology), stimuli) on receptors that generate Action potential, impulses that travel through nerves to the brain (afferents). There are sensory receptors on or near the surface of the body, such as photoreceptors in the retina of the eye, hair cells in the cochlea of the ear, touch receptors in the skin and chemical receptors in the mouth and nasal cavity. There are also sensory receptors in the muscles, joints ...
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Online Etymology Dictionary
Etymonline, or ''Online Etymology Dictionary'', sometimes abbreviated as OED (not to be confused with the ''Oxford English Dictionary'', which the site often cites), is a free online dictionary that describes the etymology, origins of English language, English words, written and compiled by Douglas R. Harper. Description Douglas R. Harper is an American Civil War historian and copy editor for LNP Media Group. He compiled the etymology dictionary to record the history and evolution of more than 50,000 words, including slang and technical terms. The core of its etymology information stems from ''The Barnhart Dictionary of Etymology'' by Robert Barnhart, Ernest Klein's ''Comprehensive Etymology Dictionary of the English Language'', ''The Middle English Compendium'', ''The Oxford English Dictionary'', and the 1889–1902 ''Century Dictionary''. Harper also researches on digital archives. On the ''Etymonline'' homepage, Harper says that he considers himself "essentially and for the m ...
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Thomas Sydenham
Thomas Sydenham (; 10 September 1624 – 29 December 1689) was an England, English physician. He was the author of ''Observationes Medicae'' (1676) which became a standard textbook of medicine for two centuries so that he became known as 'The English Hippocrates'. Among his many achievements was the discovery of a disease, Sydenham's chorea, also known as St Vitus' Dance. To him is attributed the prescient dictum, "A man is as old as his arteries." Early life Thomas Sydenham was born at Wynford Eagle in Dorset, where his father was a gentleman of property. His brother was Colonel William Sydenham. At the age of eighteen Sydenham attended Magdalen Hall, Oxford; after a short period his college studies appear to have been interrupted, and he served for a time as an officer in the Parliamentarian army during the Civil War. He completed his Oxford course in 1648, graduating as bachelor of medicine, and about the same time he was elected a fellow of All Souls College, Oxford, All ...
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White Matter
White matter refers to areas of the central nervous system that are mainly made up of myelinated axons, also called Nerve tract, tracts. Long thought to be passive tissue, white matter affects learning and brain functions, modulating the distribution of action potentials, acting as a relay and coordinating communication between different brain regions. White matter is named for its relatively light appearance resulting from the lipid content of myelin. Its white color in prepared specimens is due to its usual preservation in formaldehyde. It appears pinkish-white to the naked eye otherwise, because myelin is composed largely of lipid tissue veined with capillaries. Structure White matter White matter is composed of bundles, which connect various grey matter areas (the locations of nerve cell bodies) of the brain to each other, and carry nerve impulses between neurons. Myelin acts as an insulator, which allows saltatory conduction, electrical signals to jump, rather than cour ...
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Apoplexy
Apoplexy () refers to the rupture of an internal organ and the associated symptoms. Informally or metaphorically, the term ''apoplexy'' is associated with being furious, especially as "apoplectic". Historically, it described what is now known as a hemorrhagic stroke, typically involving a ruptured blood vessel in the brain; modern medicine typically specifies the anatomical location of the bleeding, such as cerebral apoplexy, ovarian apoplexy, or pituitary apoplexy. Historical meaning From the late 14th to the late 19th century, the diagnosis ''apoplexy'' referred to any sudden death that began with abrupt loss of consciousness, especially when the victim died within seconds after losing consciousness. The word ''apoplexy'' was sometimes used to refer to the symptom of sudden loss of consciousness immediately preceding death. Strokes, ruptured aortic aneurysms, and even heart attacks were referred to as apoplexy in the past, because before the advent of biomedical scienc ...
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Lethargy
Lethargy is a state of tiredness, sleepiness, weariness, fatigue, sluggishness, or lack of energy. It can be accompanied by depression, decreased motivation, or apathy. Lethargy can be a normal response to inadequate sleep, overexertion, overworking, stress, lack of exercise, improper nutrition, drug abuse, boredom, or a symptom of an underlying illness or disorder. It may also be a side effect of medication or caused by an interaction between medications or medication(s) and alcohol. It may also be an altered level of consciousness. When part of a normal response, lethargy often resolves with rest, adequate sleep, decreased stress, physical exercise, and good nutrition. Its symptoms, however, can last days or even months, so it can be a sign of a recent underlying illness or infection if it does not resolve normally. See also * Clinical depression * Disorders of diminished motivation * Encephalitis lethargica * Sleep apnea * Sleep deprivation * Somnolence Somnolence ( ...
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Thomas Willis
Thomas Willis Fellow of the Royal Society, FRS (27 January 1621 – 11 November 1675) was an English physician who played an important part in the history of anatomy, neurology, and psychiatry, and was a founding member of the Royal Society. Life Willis was born on his parents' farm in Great Bedwyn, Wiltshire, where his father held the stewardship of the manor. He was a kinsman of the Willys baronets of Fen Ditton, Cambridgeshire. He graduated Master of Arts, M.A. from Christ Church, Oxford in 1642.Willis, Thomas
The Galileo Project. Galileo.rice.edu. Retrieved on 17 July 2012.
In the Civil War years he was a Royalist, dispossessed of the family farm at North Hinksey by Roundheads, Parliamentary forces. In the 1640s, Willis was one of the royal physicians to Charles I of England, Charles I. Once q ...
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Galen
Aelius Galenus or Claudius Galenus (; September 129 – AD), often Anglicization, anglicized as Galen () or Galen of Pergamon, was a Ancient Rome, Roman and Greeks, Greek physician, surgeon, and Philosophy, philosopher. Considered to be one of the most accomplished of all medical researchers of Ancient history, antiquity, Galen influenced the development of various scientific disciplines, including anatomy, physiology, pathology, pharmacology, and neurology, as well as philosophy and logic. The son of Aelius Nicon, a wealthy Greek architect with scholarly interests, Galen received a comprehensive education that prepared him for a successful career as a physician and philosopher. Born in the ancient city of Pergamon (present-day Bergama, Turkey), Galen traveled extensively, exposing himself to a wide variety of medical theories and discoveries before settling in Ancient Rome, Rome, where he served prominent members of Roman society and eventually was given the position of perso ...
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