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Clonorchiasis
Clonorchiasis is an infectious disease caused by the Chinese liver fluke (''Clonorchis sinensis'') and two related species. Clonorchiasis is a known risk factor for the development of cholangiocarcinoma, a neoplasm of the biliary system. Symptoms of opisthorchiasis caused by ''Opisthorchis viverrini'' and by '' O. felineus'' are indistinguishable from clonorchiasis caused by '' Clonorchis sinensis'', leading some to argue that the disease by these three parasites should be referred to collectively as clonorchiasis.. Signs and symptoms Cause ''Clonorchis sinensis'' is a trematode (fluke) which is part of the phylum Platyhelminthes. The parasitic worm is as long as 10 to 25 mm and lives in the bile ducts of the liver. It is a hermaphroditic fluke that requires two intermediate hosts. The eggs of the worms are passed in fecal matter into a body of water and are then ingested by mollusks. The water snail is the first intermediate host, in which a miracidium (an embryonat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clonorchis Sinensis
''Clonorchis sinensis'', the Chinese liver fluke, is a liver fluke belonging to the class trematode, Trematoda, phylum Platyhelminthes. It infects fish-eating mammals, including humans. In humans, it infects the common bile duct and gall bladder, feeding on bile. It was discovered by British physician James McConnell at the Medical College Hospital in Calcutta (Kolkata) in 1874. The first description was given by Thomas Spencer Cobbold, who named it ''Distoma sinense''. The fluke passes its lifecycle in three different hosts, namely freshwater snail as first intermediate hosts, freshwater fish as second intermediate host, and mammals as definitive hosts. Endemic to Asia and Russia, ''C. sinensis'' is the most prevalent human fluke in Asia and third-most in the world. It is still actively transmitted in Korea, China, Vietnam, and Russia. Most infections (about 85%) occur in China. The infection, called clonorchiasis, generally appears as jaundice, indigestion, biliary inflammation, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trematode
Trematoda is a Class (biology), class of flatworms known as trematodes, and commonly as flukes. They are obligate parasite, obligate Endoparasites, internal parasites with a complex biological life cycle, life cycle requiring at least two Host (biology), hosts. The intermediate host, in which asexual reproduction occurs, is a Mollusca, mollusk, usually a snail. The definitive host, where the flukes Sexual reproduction, sexually reproduce, is a vertebrate. Infection by trematodes can cause disease in all five vertebrate classes: mammals, birds, amphibians, reptiles, and fish. Etymology Trematodes are commonly referred to as flukes. This term can be traced back to the Old English name for flounder, and refers to the flattened, rhomboidal shape of the organisms. The etymology of trematode stems from the Ancient Greek, Greek word ''trēmatṓdēs'', which means "pierced with holes", and refers to the worm's sucker (zoology), sucker, which pierces a hole in the host while the worm is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cholangiocarcinoma
Cholangiocarcinoma, also known as bile duct cancer, is a type of cancer that forms in the bile ducts. Symptoms of cholangiocarcinoma may include abdominal pain, yellowish skin, weight loss, generalized itching, and fever. Light colored stool or dark urine may also occur. Other biliary tract cancers include gallbladder cancer and cancer of the ampulla of Vater. Risk factors for cholangiocarcinoma include primary sclerosing cholangitis (an inflammatory disease of the bile ducts), ulcerative colitis, cirrhosis, hepatitis C, hepatitis B, infection with certain liver flukes, and some congenital liver malformations. Most people have no identifiable risk factors. The diagnosis is suspected based on a combination of blood tests, medical imaging, endoscopy, and sometimes surgical exploration. The disease is confirmed by examination of cells from the tumor under a microscope. It is typically an adenocarcinoma (a cancer that forms glands or secretes mucin). Cholangiocarcinoma is ty ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Helminthiases
Helminthiasis, also known as worm infection, is any macroparasitic disease of humans and other animals in which a part of the body is infected with parasitic worms, known as helminths. There are numerous species of these parasites, which are broadly classified into tapeworms, flukes, and roundworms. They often live in the gastrointestinal tract of their hosts, but they may also burrow into other organs, where they induce physiological damage. Soil-transmitted helminthiasis and schistosomiasis are the most important helminthiases, and are among the neglected tropical diseases. These group of helminthiases have been targeted under the joint action of the world's leading pharmaceutical companies and non-governmental organizations through a project launched in 2012 called the London Declaration on Neglected Tropical Diseases, which aimed to control or eradicate certain neglected tropical diseases by 2020. Helminthiasis has been found to result in poor birth outcome, poor cognitiv ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Praziquantel
Praziquantel, sold under the brandname Biltricide among others, is a medication used to treat a number of types of parasitic worm infections in mammals, birds, amphibians, reptiles, and fish. In humans specifically, it is used to treat schistosomiasis, clonorchiasis, opisthorchiasis, tapeworm infections, cysticercosis, echinococcosis, paragonimiasis, fasciolopsiasis, and fasciolosis. It should not be used for worm infections of the eye. It is taken by mouth. Side effects in humans may include poor coordination, abdominal pain, vomiting, headache, and allergic reactions. While it may be used during pregnancy, it is not recommended for use during breastfeeding. Praziquantel is in the anthelmintic class of medications. It works partly by affecting the function of the worm's sucker. Praziquantel was approved for medical use in the United States in 1982, and in the European Union in April 2025. It is on the World Health Organization's List of Essential Medicines. Medic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Infectious Disease
An infection is the invasion of tissue (biology), tissues by pathogens, their multiplication, and the reaction of host (biology), host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable disease, is an Disease#Terminology, illness resulting from an infection. Infections can be caused by a wide range of pathogens, most prominently pathogenic bacteria, bacteria and viruses. Hosts can fight infections using their immune systems. Mammalian hosts react to infections with an Innate immune system, innate response, often involving inflammation, followed by an Adaptive immune system, adaptive response. Treatment for infections depends on the type of pathogen involved. Common medications include: * Antibiotics for bacterial infections. * Antivirals for viral infections. * Antifungals for fungal infections. * Antiprotozoals for protozoan infections. * Antihelminthics for infections caused by parasi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cercaria
A cercaria (plural cercariae) is a larval form of the trematode class of parasites. It develops within the germinal cells of the Trematode life cycle stages, sporocyst or redia. A cercaria has a tapering head with large penetration glands. It may or may not have a long swimming "tail", depending on the species. The motile cercaria finds and settles in a host where it will become either an adult, or a mesocercaria, or a metacercaria, according to species. Cercarial infection in water environments by non-human Schistosomatidae, schistosome species causes dermatologic burden to nearby swimmers, fishermen and farmers. The cycle as mentioned above, starts with egg distribution whether fecal in route or from the nostril of a duck or goose. Miracidia infect snail reservoirs and form successive sporocysts. Released cercariae travel and infect nearby non-human mammals or birds, depending on species, or accidental hosts such as humans. This dead-end infection and host allergic reaction ha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hepatology
Hepatology is the branch of medicine that incorporates the study of liver, gallbladder, biliary tree, and pancreas as well as management of their disorders. Although traditionally considered a sub-specialty of gastroenterology, rapid expansion has led in some countries to doctors specializing solely on this area, who are called hepatologists. Diseases and complications related to viral hepatitis and alcohol are the main reason for seeking specialist advice. More than two billion people have been infected with hepatitis B virus at some point in their life, and approximately 350 million have become persistent carriers. Up to 80% of liver cancers can be attributed to either hepatitis B or hepatitis C virus. In terms of Mortality rate, mortality, the former is second only to smoking among known agents causing cancer. With more widespread implementation of vaccination and strict Screening (medicine), screening before blood transfusion, lower infection rates are expected in the futur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Health And Family Planning Commission
The National Health and Family Planning Commission of the People's Republic of China (NHFPC) was a Ministries of the People's Republic of China, cabinet-level executive department under the State Council of the People's Republic of China, State Council which is responsible for providing information, raising health awareness and education, family planning, ensuring the accessibility of health services, monitoring the quality of health services provided to citizens and visitors in the mainland China, mainland, population and family planning in the People's Republic of China. In March 2018, the ministry was dissolved and its functions were integrated into the new agency called the National Health Commission. History The Ministry is created from the former Ministry of Health of the People's Republic of China, Ministry of Health and National Population and Family Planning Commission. This was announced at the 2013 National People's Congress. From 16 March 2013 to March 2018, the com ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Metacercariae
Trematodes are parasitic flatworms of the class ''Trematoda'', specifically parasitic flukes with two Sucker (zoology), suckers: one ventral and the other Mouth, oral. Trematodes are covered by a Tegument (helminth), tegument, that protects the organism from the environment by providing secretory and absorptive functions. The life cycle of a typical trematode begins with an egg. Some trematode eggs hatch directly in the environment (water), while others are eaten and hatched within a host, typically a mollusc. The hatchling is called a ''miracidium,'' a free-swimming, ciliated larva. Miracidia will then grow and develop within the intermediate host into a sac-like structure known as a sporocyst or into rediae, either of which may give rise to free-swimming, motile cercariae larvae. The cercariae then could either infect a vertebrate host or a second intermediate host. Adult metacercariae or mesocercariae, depending on the individual trematode's life cycle, will then infect the ve ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Far East
The Far East is the geographical region that encompasses the easternmost portion of the Asian continent, including North Asia, North, East Asia, East and Southeast Asia. South Asia is sometimes also included in the definition of the term. In modern times, the term ''Far East'' has widely fallen out of use and been substituted by Asia–Pacific, while the terms Middle East and Near East, although now pertaining to different territories, are still commonly used today. The term first came into use in European geopolitical discourse in the 15th century, particularly the British people, British, denoting the Far East as the "farthest" of the three "Easts", beyond the Near East and the Middle East. Likewise, during the Qing dynasty of the 19th and early 20th centuries, the term "Far West (Taixi), Tàixī ()" – i.e., anything further west than the Arab world – was used to refer to the Western countries. Since the mid-20th century, the term has mostly gone out of use for the region ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Endemic
Endemism is the state of a species being found only in a single defined geographic location, such as an island, state, nation, country or other defined zone; organisms that are indigenous to a place are not endemic to it if they are also found elsewhere. For example, the Cape sugarbird is found exclusively in southwestern South Africa and is therefore said to be ''endemic'' to that particular part of the world. An endemic species can also be referred to as an ''endemism'' or, in scientific literature, as an ''endemite''. Similarly, many species found in the Western ghats of India are examples of endemism. Endemism is an important concept in conservation biology for measuring biodiversity in a particular place and evaluating the risk of extinction for species. Endemism is also of interest in evolutionary biology, because it provides clues about how changes in the environment cause species to undergo range shifts (potentially expanding their range into a larger area or bec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
