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CiteAb
CiteAb Limited is a life science data company located in Bath, England that offers an antibody, biochemicals, experimental models, kits and protein search tool to aid biomedical scientists in their research. History and operations CiteAb started in 2013 as an academic project by Dr Andrew Chalmers, a senior lecturer at the University of Bath. The resource was established to help scientific researchers find suitable antibodies for their experiments - such antibodies can be helpful in context of screenings, therapeutic development, and drug discovery. CiteAb ranks antibodies by citations, making it possible for researchers to find reagents that have been successfully used in past research papers. The accompanying citations are listed, so the data contained within the publications can also be checked. The CiteAb platform was built in collaboration with technology company Storm Consultancy, in Bath, in 2012. A trial website was soft-launched in September 2012 before the full ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biotech
Biotechnology is a multidisciplinary field that involves the integration of natural sciences and engineering sciences in order to achieve the application of organisms and parts thereof for products and services. Specialists in the field are known as biotechnologists. The term ''biotechnology'' was first used by Károly Ereky in 1919 to refer to the production of products from raw materials with the aid of living organisms. The core principle of biotechnology involves harnessing biological systems and organisms, such as bacteria, yeast, and plants, to perform specific tasks or produce valuable substances. Biotechnology had a significant impact on many areas of society, from medicine to agriculture to environmental science. One of the key techniques used in biotechnology is genetic engineering, which allows scientists to modify the genetic makeup of organisms to achieve desired outcomes. This can involve inserting genes from one organism into another, and consequently, create ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Life Sciences
This list of life sciences comprises the branches of science that involve the scientific study of life – such as microorganisms, plants, and animals including human beings. This science is one of the two major branches of natural science, the other being physical science, which is concerned with non-living matter. Biology is the overall natural science that studies life, with the other life sciences as its sub-disciplines. Some life sciences focus on a specific type of organism. For example, zoology is the study of animals, while botany is the study of plants. Other life sciences focus on aspects common to all or many life forms, such as anatomy and genetics. Some focus on the micro-scale (e.g. molecular biology, biochemistry) other on larger scales (e.g. cytology, immunology, ethology, pharmacy, ecology). Another major branch of life sciences involves understanding the mindneuroscience. Life sciences discoveries are helpful in improving the quality and standard of life ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antibody
An antibody (Ab) or immunoglobulin (Ig) is a large, Y-shaped protein belonging to the immunoglobulin superfamily which is used by the immune system to identify and neutralize antigens such as pathogenic bacteria, bacteria and viruses, including those that cause disease. Each individual antibody recognizes one or more specific antigens, and antigens of virtually any size and chemical composition can be recognized. Antigen literally means "antibody generator", as it is the presence of an antigen that drives the formation of an antigen-specific antibody. Each of the branching chains comprising the "Y" of an antibody contains a paratope that specifically binds to one particular epitope on an antigen, allowing the two molecules to bind together with precision. Using this mechanism, antibodies can effectively "tag" the antigen (or a microbe or an infected cell bearing such an antigen) for attack by cells of the immune system, or can neutralize it directly (for example, by blocking a p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bath, Somerset
Bath (Received Pronunciation, RP: , ) is a city in Somerset, England, known for and named after its Roman Baths (Bath), Roman-built baths. At the 2021 census, the population was 94,092. Bath is in the valley of the River Avon, Bristol, River Avon, west of London and southeast of Bristol. The city became a UNESCO World Heritage Site in 1987, and was later added to the transnational World Heritage Site known as the "Great Spa Towns of Europe" in 2021. Bath is also the largest city and settlement in Somerset. The city became a spa with the Latin name ' ("the waters of Sulis") 60 AD when the Romans built Roman Baths (Bath), baths and a temple in the valley of the River Avon, although List of geothermal springs in the United Kingdom, hot springs were known even before then. Bath Abbey was founded in the 7th century and became a religious centre; the building was rebuilt in the 12th and 16th centuries. In the 17th century, claims were made for the curative properties of water ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Bath
The University of Bath is a public research university in Bath, England. Bath received its royal charter in 1966 as Bath University of Technology, along with a number of other institutions following the Robbins Report. Like the University of Bristol and University of the West of England, Bath can trace its roots to the Merchant Venturers' Technical College, established in Bristol as a school in 1595 by the Society of Merchant Venturers. The university's main campus is located on Claverton Down, a site overlooking the UNESCO World Heritage city of Bath, and was purpose-built, constructed from 1964 in the modernist style of the times. In the 2021 Research Excellence Framework, 40% of Bath's submitted research activity achieved the highest possible classification of 4*, defined as world-leading in terms of originality, significance and rigour. 92% was graded 4*/3*, defined as world-leading/internationally excellent. The annual income of the institution for 2023–24 was � ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
High-content Screening
High-content screening (HCS), also known as high-content analysis (HCA) or cellomics, is a method that is used in biological research and drug discovery to identify substances such as small molecules, peptides, or RNAi that alter the phenotype of a cell in a desired manner. Hence high content screening is a type of phenotypic screen conducted in cells involving the analysis of whole cells or components of cells with simultaneous readout of several parameters. HCS is related to high-throughput screening (HTS), in which thousands of compounds are tested in parallel for their activity in one or more biological assays, but involves assays of more complex cellular phenotypes as outputs. Phenotypic changes may include increases or decreases in the production of cellular products such as proteins and/or changes in the morphology (visual appearance) of the cell. Hence HCA typically involves automated microscopy and image analysis. Unlike high-content analysis, high-content screening im ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Monoclonal Antibody Therapy
Monoclonal antibodies (mAbs) have varied therapeutic uses. It is possible to create a mAb that binds specifically to almost any extracellular target, such as cell surface proteins and cytokines. They can be used to render their target ineffective (e.g. by preventing receptor binding), to induce a specific cell signal (by activating receptors), to cause the immune system to attack specific cells, or to bring a drug to a specific cell type (such as with radioimmunotherapy which delivers cytotoxic radiation). Major applications include cancer, autoimmune diseases, asthma, organ transplants, blood clot prevention, and certain infections. Antibody structure and function Immunoglobulin G ( IgG) antibodies are large heterodimeric molecules, approximately 150 kDa and are composed of two kinds of polypeptide chain, called the heavy (~50kDa) and the light chain (~25kDa). The two types of light chains are kappa (κ) and lambda (λ). By cleavage with enzyme papain, the Fab (''f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Engineering And Physical Sciences Research Council
The Engineering and Physical Sciences Research Council (EPSRC) is a British UK Research Councils, Research Council that provides government funding for grants to undertake research and postgraduate degrees in engineering and the physical sciences, mainly to universities in the United Kingdom. EPSRC research areas include mathematics, physics, chemistry, artificial intelligence and computer science, but exclude particle physics, nuclear physics, space science and astronomy (which fall under the remit of the Science and Technology Facilities Council). Since 2018 it has been part of UK Research and Innovation, which is funded through the Department for Business, Energy and Industrial Strategy. History EPSRC was created in 1994. At first part of the Science and Engineering Research Council (SERC), in 2018 it was one of nine organisations brought together to form UK Research and Innovation (UKRI). Its head office is in Swindon, Wiltshire in the same building (Polaris House) that hou ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Higher Education Funding Council For England
The Higher Education Funding Council for England (HEFCE) was a non-departmental public body in the United Kingdom, which was responsible for the distribution of funding for higher education to universities and further education colleges in England since 1992. It ceased to exist as of 1 April 2018, when its duties were divided between the newly created Office for Students and Research England (operating within United Kingdom Research and Innovation). Most universities are charities and HEFCE (rather than the Charity Commission for England and Wales) was their principal regulator. HEFCE therefore had the duty to promote compliance with charity law by the universities for which it was responsible. History HEFCE was created by the Further and Higher Education Act 1992 (which also created the Further Education Funding Council for England (FEFC), replaced in 2001 by the Learning and Skills Council). On 1 June 2010 HEFCE became the principal regulator of those higher education instit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Local Enterprise Partnership
In England, local enterprise partnerships (LEPs) were voluntary partnerships between local authorities and businesses, set up in 2011 by the Department for Business, Innovation and Skills to help determine local economic priorities and lead economic growth and job creation within the local area. They carried out some of the functions previously carried out by the regional development agencies which were abolished in March 2012. In certain areas, funding was received from the UK government via growth deals. Funding for LEPs was withdrawn by the Rishi Sunak Conservative government in April 2024 and their functions were assumed by local authorities, some of whom have formed Business Boards as replacements. History The abolition of regional development agencies and the creation of local enterprise partnerships were announced as part of the June 2010 United Kingdom budget. On 29 June 2010, a letter was sent from the Department for Communities and Local Government and the Depa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biotechnology Companies Of The United Kingdom
Biotechnology is a multidisciplinary field that involves the integration of natural sciences and engineering sciences in order to achieve the application of organisms and parts thereof for products and services. Specialists in the field are known as biotechnologists. The term ''biotechnology'' was first used by Károly Ereky in 1919 to refer to the production of products from raw materials with the aid of living organisms. The core principle of biotechnology involves harnessing biological systems and organisms, such as bacteria, yeast, and plants, to perform specific tasks or produce valuable substances. Biotechnology had a significant impact on many areas of society, from medicine to agriculture to environmental science. One of the key techniques used in biotechnology is genetic engineering, which allows scientists to modify the genetic makeup of organisms to achieve desired outcomes. This can involve inserting genes from one organism into another, and consequently, create n ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
