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CURB-65
CURB-65, also known as the CURB criteria, is a clinical prediction rule that has been validated for predicting mortality in community-acquired pneumonia and infection of any site. The CURB-65 is based on the earlier CURB score and is recommended by the British Thoracic Society for the assessment of severity of pneumonia. It was developed in 2002 at the University of Nottingham by Dr. W.S. Lim et al. In 2018 a new toolkit was presented on the basis of CURB-65. The score is an acronym for each of the risk factors measured. Each risk factor scores one point, for a maximum score of 5: * Confusion of new onset (defined as an AMTS of 8 or less) * Blood Urea nitrogen greater than 7 mmol/L (19 mg/dL) * Respiratory rate of 30 breaths per minute or greater * Blood pressure less than 90 mmHg systolic or diastolic blood pressure 60 mmHg or less * Age 65 or older Predicting death Pneumonia The risk of death at 30 days increases as the score increases: * 0—0.7% * 1—3.2% * ...
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Pneumonia Severity Index
The pneumonia severity index (PSI) or PORT Score is a clinical prediction rule that medical practitioners can use to calculate the probability of morbidity and mortality among patients with community acquired pneumonia. The PSI/PORT score is often used to predict the need for hospitalization in people with pneumonia. This is consistent with the conclusions stated in the original report that published the PSI/PORT score: "The prediction rule we describe accurately identifies the patients with community-acquired pneumonia who are at low risk for death and other adverse outcomes. This prediction rule may help physicians make more rational decisions about hospitalization for patients with pneumonia." Mortality prediction is similar to that when using CURB-65. Development The rule uses demographics (whether someone is older, and is male or female), the coexistence of co-morbid illnesses, findings on physical examination and vital signs, and essential laboratory findings. This study ...
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Clinical Prediction Rule
A clinical prediction rule or clinical probability assessment specifies how to use medical signs, symptoms, and other findings to estimate the probability of a specific disease or clinical outcome. Physicians have difficulty in estimated risks of diseases; frequently erring towards overestimation, perhaps due to cognitive biases such as base rate fallacy in which the risk of an adverse outcome is exaggerated. Methods In a prediction rule study, investigators identify a consecutive group of patients who are suspected of having a specific disease or outcome. The investigators then obtain a standard set of clinical observations on each patient and a test or clinical follow-up to define the true state of the patient. They then use statistical methods to identify the best clinical predictors of the patient's true state. The probability of disease will depend on the patient's key clinical predictors. Published methodological standards specify good practices for developing a clinical pred ...
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Community-acquired Pneumonia
Community-acquired pneumonia (CAP) refers to pneumonia (any of several lung diseases) contracted by a person outside of the healthcare system. In contrast, hospital-acquired pneumonia (HAP) is seen in patients who have recently visited a hospital or who live in long-term care facilities. CAP is common, affecting people of all ages, and its symptoms occur as a result of oxygen-absorbing areas of the lung ( alveoli) filling with fluid. This inhibits lung function, causing dyspnea, fever, chest pains and cough. CAP, the most common type of pneumonia, is a leading cause of illness and death worldwide. Its causes include bacteria, viruses, fungi and parasites. CAP is diagnosed by assessing symptoms, performing a physical examination, by x-ray or by sputum examination. Patients with CAP sometimes require hospitalization, and it is treated primarily with antibiotics, antipyretics and cough medicine. Some forms of CAP can be prevented by vaccination and by abstaining from tobacco products ...
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British Thoracic Society
The British Thoracic Society (BTS) was formed in 1982 by the amalgamation of the British Thoracic Association and the Thoracic Society. It is a registered charity and a company limited by guarantee. Function The society's main charitable objective is to improve the care of people with respiratory and associated disorders, which it aims to achieve by: * promoting optimum standards of care (the Clinical Information section of the BTS website contains treatment Guidelines, good practice guides and related audit tools) * promoting and advancing knowledge about the causes, prevention and treatment of respiratory diseases (the society runs two large conferences each year and a range of short courses and are currently developing an e-learning resource - more details of these can be found in the Education Hub) * promoting and disseminating research (the society's Winter Meeting is the main showcase for this activity, as well as the journal Thorax, published jointly with the British Med ...
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University Of Nottingham
The University of Nottingham is a public university, public research university in Nottingham, United Kingdom. It was founded as University College Nottingham in 1881, and was granted a royal charter in 1948. The University of Nottingham belongs to the research intensive Russell Group association. Nottingham's main campus (University Park Campus, Nottingham, University Park) with Jubilee Campus and teaching hospital (Queen's Medical Centre) are located within the City of Nottingham, with a number of smaller campuses and sites elsewhere in Nottinghamshire and Derbyshire. Outside the UK, the university has campuses in Semenyih, Malaysia, and Ningbo, China. Nottingham is organised into five constituent faculties, within which there are more than 50 schools, departments, institutes and research centres. Nottingham has about 45,500 students and 7,000 staff, and had an income of £694 million in 2020–21, of which £114.9 million was from research grants and contracts. The institution's ...
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Acronym
An acronym is a word or name formed from the initial components of a longer name or phrase. Acronyms are usually formed from the initial letters of words, as in '' NATO'' (''North Atlantic Treaty Organization''), but sometimes use syllables, as in '' Benelux'' (short for ''Belgium, the Netherlands, and Luxembourg''). They can also be a mixture, as in '' radar'' (''Radio Detection And Ranging''). Acronyms can be pronounced as words, like '' NASA'' and '' UNESCO''; as individual letters, like ''FBI'', '' TNT'', and ''ATM''; or as both letters and words, like ''JPEG'' (pronounced ') and ''IUPAC''. Some are not universally pronounced one way or the other and it depends on the speaker's preference or the context in which it is being used, such as '' SQL'' (either "sequel" or "ess-cue-el"). The broader sense of ''acronym''—the meaning of which includes terms pronounced as letters—is sometimes criticized, but it is the term's original meaning and is in common use. Dictionary ...
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Abbreviated Mental Test Score
The Abbreviated Mental Test score (AMTS) is a 10-point test for rapidly assessing elderly patients for the possibility of dementia. It was first used in 1972, and is now sometimes also used to assess for mental confusion (including delirium) and other cognitive impairments. A 4-item version called the Abbreviated Mental Test - 4 (AMT4) has been developed and tested. Questionnaire The following questions are put to the patient. Each question correctly answered scores one point. A score of 7–8 or less suggests cognitive impairment at the time of testing, although further and more formal tests are necessary to confirm a diagnosis of dementia, delirium or other causes of cognitive impairment. Culturally-specific questions may vary based on region. Abbreviated Mental Test - 4 (AMT4) The AMT4 uses 4 items from the AMTS: (i) What is your age? (ii) What is your date of birth? (iii) What is the name of this place? (iv) What is the year? A cut off score of 3/4 performs comparably to a ...
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Diagnostic Intensive Care Medicine
Diagnosis is the identification of the nature and cause of a certain phenomenon. Diagnosis is used in many different disciplines, with variations in the use of logic, analytics, and experience, to determine " cause and effect". In systems engineering and computer science, it is typically used to determine the causes of symptoms, mitigations, and solutions. Computer science and networking * Bayesian networks * Complex event processing * Diagnosis (artificial intelligence) * Event correlation * Fault management * Fault tree analysis * Grey problem * RPR Problem Diagnosis * Remote diagnostics * Root cause analysis * Troubleshooting * Unified Diagnostic Services Mathematics and logic * Bayesian probability * Block Hackam's dictum * Occam's razor * Regression diagnostics * Sutton's law copy right remover block Medicine * Medical diagnosis * Molecular diagnostics Methods * CDR Computerized Assessment System * Computer-assisted diagnosis * Differential diagnosis * Medical ...
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Medical Scales
Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of skill and knowledge), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, ...
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Science And Technology In Nottinghamshire
Science is a systematic endeavor that builds and organizes knowledge in the form of testable explanations and predictions about the universe. Science may be as old as the human species, and some of the earliest archeological evidence for scientific reasoning is tens of thousands of years old. The earliest written records in the history of science come from Ancient Egypt and Mesopotamia in around 3000 to 1200 BCE. Their contributions to mathematics, astronomy, and medicine entered and shaped Greek natural philosophy of classical antiquity, whereby formal attempts were made to provide explanations of events in the physical world based on natural causes. After the fall of the Western Roman Empire, knowledge of Greek conceptions of the world deteriorated in Western Europe during the early centuries (400 to 1000 CE) of the Middle Ages, but was preserved in the Muslim world during the Islamic Golden Age and later by the efforts of Byzantine Greek scholars who brought Greek ma ...
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