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CEBPZ
CCAAT/enhancer-binding protein zeta is a protein that in humans is encoded by the ''CEBPZ'' gene. Interactions CCAAT/enhancer binding protein zeta has been shown to interact with: * NFYB, * P53, * P73 See also * Ccaat-enhancer-binding proteins CCAAT-enhancer-binding proteins (or C/EBPs) is a Protein family, family of transcription factors composed of six members, named from C/EBPα to C/EBPζ. They promote the expression of certain genes through interaction with their Promoter (biology ... References Further reading * * * * * * * * External links * * * Transcription factors {{gene-2-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
NFYB
Nuclear transcription factor Y subunit beta is a protein that in humans is encoded by the ''NFYB'' gene. Function The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. Interactions NFYB has been shown to interact with: * CEBPZ CCAAT/enhancer-binding protein zeta is a protein that in humans is encoded by the ''CEBPZ'' gene. Interactions CCAAT/enhancer binding protein zeta has been shown to interact with: * NFYB, * P53, * P73 Se ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ccaat-enhancer-binding Proteins
CCAAT-enhancer-binding proteins (or C/EBPs) is a Protein family, family of transcription factors composed of six members, named from C/EBPα to C/EBPζ. They promote the expression of certain genes through interaction with their Promoter (biology), promoters. Once bound to DNA, C/EBPs can recruit so-called co-activators (such as CBP) that in turn can open up chromatin structure or recruit basal transcription factors. Function C/EBP proteins interact with the CCAAT (cytosine-cytosine-adenosine-adenosine-thymidine) box motif, which is present in several gene promoters. They are characterized by a highly conservation (genetics), conserved bZIP domain, basic-leucine zipper (bZIP) domain at the C-terminus. This domain is involved in protein dimer, dimerization and DNA binding, as are other transcription factors of the leucine zipper domain-containing family (''c-Fos'' and ''c-jun''). The bZIP domain structure of C/EBPs is composed of an α-helix that forms a "coiled coil" structure ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metabolic reactions, DNA replication, Cell signaling, responding to stimuli, providing Cytoskeleton, structure to cells and Fibrous protein, organisms, and Intracellular transport, transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the Nucleic acid sequence, nucleotide sequence of their genes, and which usually results in protein folding into a specific Protein structure, 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called pep ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and non-coding genes. During gene expression (the synthesis of Gene product, RNA or protein from a gene), DNA is first transcription (biology), copied into RNA. RNA can be non-coding RNA, directly functional or be the intermediate protein biosynthesis, template for the synthesis of a protein. The transmission of genes to an organism's offspring, is the basis of the inheritance of phenotypic traits from one generation to the next. These genes make up different DNA sequences, together called a genotype, that is specific to every given individual, within the gene pool of the population (biology), population of a given species. The genotype, along with environmental and developmental factors, ultimately determines the phenotype ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
