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C15H10O5
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The chemical formula C15H10O5 (molar mass : 270.23 g/mol, exact mass : 270.052823) may refer to: * Trihydroxyflavones: ** Apigenin (5,7,4'-trihydroxyflavone) ** Baicalein (5,6,7-trihydroxyflavone) ** Galangin (3,5,7-trihydroxyflavone) ** Norwogonin (5,7,8-Trihydroxyflavone) ** 7,8,3'-Trihydroxyflavone ** 6,7,4'-Trihydroxyflavone * Aloe emodin, an anthraquinone * Emodin, a purgative resin * Genistein, an isoflavone * Morindone, an anthraquinone dye * Thunberginol A, an isocoumarin * Thunberginol F, a natural benzofuran See also * List of compounds with carbon number 15 This is a partial list of molecules that contain 15 carbon atoms. See also * Carbon number * List of compounds with carbon number 14 This is a partial list of molecules that contain 14 carbon atoms. See also * Carbon number * List of com ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Apigenin
Apigenin (4′,5,7-trihydroxyflavone), found in many plants, is a natural product belonging to the flavone class that is the aglycone of several naturally occurring glycosides. It is a yellow crystalline solid that has been used to dye wool. Sources in nature Apigenin is found in many fruits and vegetables, but parsley, celery, celeriac, and chamomile tea are the most common sources. Apigenin is particularly abundant in the flowers of chamomile plants, constituting 68% of total flavonoids. Dried parsley can contain about 45 mg apigenin/gram of the herb, and dried chamomile flower about 3-5 mg/gram. The apigenin content of fresh parsley is reportedly 215.5 mg/100 grams, which is much higher than the next highest food source, green celery hearts providing 19.1 mg/100 grams. Biosynthesis Apigenin is biosynthetically derived from the general phenylpropanoid pathway and the flavone synthesis pathway. The phenylpropanoid pathway starts from the aro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Galangin
Galangin is a flavonol, a type of flavonoid. Occurrence Galangin is found in high concentrations in plants like ''Alpinia officinarum'' (lesser galangal) and ''Helichrysum aureonitens''. It is also found in the rhizome of ''Alpinia galanga'' and in propolis. Biological activities Galangin has been shown to have ''in vitro'' antibacterial and antiviral activity. It also inhibits the growth of breast tumor cells ''in vitro ''In vitro'' (meaning in glass, or ''in the glass'') studies are performed with microorganisms, cells, or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in biology an ...''. References External links Galangin on Chemblink.com {{flavonol Flavonols Resorcinols Steroid sulfotransferase inhibitors ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Emodin
Emodin (6-methyl-1,3,8-trihydroxyanthraquinone) is a chemical compound, of the anthraquinone family, that can be isolated from rhubarb, buckthorn, and Japanese knotweed ('' Reynoutria japonica'' syn. ''Polygonum cuspidatum''). Emodin is particularly abundant in the roots of the Chinese rhubarb (Rheum palmatum), knotweed and knotgrass (Polygonum cuspidatum and multiflorum) as well as Hawaii ‘au‘auko‘i cassia seeds or coffee weed (Semen cassia). It is specifically isolated from Rheum palmatum L. It is also produced by many species of fungi, including members of the genera '' Aspergillus'', '' Pyrenochaeta'', and '' Pestalotiopsis'', inter alia. The common name is derived from ''Rheum emodi'', a taxonomic synonym of '' Rheum australe'', (Himalayan rhubarb) and synonyms include emodol, frangula emodin, rheum emodin, 3-methyl-1,6,8-trihydroxyanthraquinone, Schüttgelb (Schuttgelb), and Persian Berry Lake. Pharmacology Emodin is an active component of several plants used in Trad ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genistein
Genistein (C15H10O5) is a naturally occurring compound that structurally belongs to a class of compounds known as isoflavones. It is described as an angiogenesis inhibitor and a phytoestrogen. It was first isolated in 1899 from the dyer's broom, ''Genista tinctoria''; hence, the chemical name. The compound structure was established in 1926, when it was found to be identical with that of prunetol. It was chemically synthesized in 1928. It has been shown to be the primary secondary metabolite of the ''Trifolium'' species and ''Glycine max L''. Natural occurrences Isoflavones such as genistein and daidzein are found in a number of plants including lupin, fava beans, soybeans, kudzu, and psoralea being the primary food source, also in the medicinal plants, ''Flemingia vestita'' and '' F. macrophylla'', and coffee. It can also be found in ''Maackia amurensis'' cell cultures. Biological effects Besides functioning as an antioxidant and anthelmintic, many isoflavones have been s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Morindone
Morindone is an anthraquinone compound obtained from various ''Morinda'' species, especially '' M. tinctoria'', but also '' M. citrifolia''. Its principal use is as a dye, but it has also been investigated for anticancer and microbial uses. Preparation Morindone is obtained from the root bark of ''M. tinctoria'' or related species in two stages. In the first step, small roots of immature plants are boiled in alcohol to obtain morindin, a yellowish substance which can also be used in dyeing. Further heating brings about hydrolysis of two glucose monomers through sublimation, leaving intensely red crystals. ''M. tinctoria'' is extensively grown in India for commercial production. Moridin content in the roots peaks in two to three years and drops off considerably after that; some attempts have been made to speed up production using tissue cultures. Use as a dye Morindone requires a mordant, and the color obtained varies depending on the substance used. Aluminum mordants give a re ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Baicalein
Baicalein (5,6,7-trihydroxyflavone) is a flavone, a type of flavonoid, originally isolated from the roots of '' Scutellaria baicalensis'' and '' Scutellaria lateriflora''. It is also reported in ''Oroxylum indicum'' (Indian trumpetflower) and '' Thyme''. It is the aglycone of baicalin. Baicalein is one of the active ingredients of Sho-Saiko-To, which is a Chinese classic herbal formula, and listed in Japan as Kampo medicine. As a Chinese herbal supplement, it is believed to enhance liver health. Baicalein, along with its analogue baicalin, is a positive allosteric modulator of the benzodiazepine site and/or a non-benzodiazepine site of the GABAA receptor. It displays subtype selectivity for α2 and α3 subunit-containing GABAA receptors. In accordance, baicalein shows anxiolytic effects in mice without incidence of sedation or myorelaxation. It is thought that baicalein, along with other flavonoids, may underlie the anxiolytic effects of ''S. baicalensis'' and ''S. late ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Norwogonin
Norwogonin, also known as 5,7,8-trihydroxyflavone (5,7,8-THF), is a flavone, a naturally occurring flavonoid-like chemical compound which is found in ''Scutellaria baicalensis'' (Baikal skullcap). It has been found to act as an agonist of the TrkB, the main signaling receptor of brain-derived neurotrophic factor (BDNF), and appears to possess roughly the same activity in this regard to that of the closely related but more well-known tropoflavin Tropoflavin, also known as 7,8-dihydroxyflavone, is a naturally occurring flavone found in ''Godmania aesculifolia'', ''Tridax procumbens'', and primula tree leaves. It has been found to act as a potent and selective small-molecule agonist of ... (7,8-DHF). See also * Tropomyosin receptor kinase B § Agonists References Flavones TrkB agonists {{aromatic-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
7,8,3'-Trihydroxyflavone
7,8,3′-Trihydroxyflavone (7,8,3'-THF) is a flavone and small-molecule agonist of TrkB, the main receptor of brain-derived neurotrophic factor (BDNF), that was derived from tropoflavin (7,8-DHF). Relative to tropoflavin, 7,8,3'-THF is 2–3-fold more potent ''in vitro'' as a TrkB agonist. 7,3’-Dihydroxyflavone (7,3'-DHF) is also more potent than tropoflavin ''in vitro'', indicating that a 3'-hydroxy group on the B-ring enhances TrkB agonistic activity. 7,8,3'-THF has been tested ''in vivo'' and was found to produce TrkB-dependent neuroprotective Neuroprotection refers to the relative preservation of neuronal structure and/or function. In the case of an ongoing insult (a neurodegenerative insult) the relative preservation of neuronal integrity implies a reduction in the rate of neuronal los ... effects in mice similarly to tropoflavin. See also * Tropomyosin receptor kinase B § Agonists References Flavones Neuroprotective agents TrkB agonists {{nervous-sys ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
6,7,4'-Trihydroxyflavone
6,7,4′-Trihydroxyflavone (6,7,4'-THF) is a flavone, a naturally occurring flavonoid-like chemical compound which is found in heartwood of ''Dalbergia odorifera ''Dalbergia odorifera'', fragrant rosewood or Chinese rosewood (), is a species of legume in the family Fabaceae. It is a small or medium-sized tree, tall. It is endemic to China and occurs in Fujian, Hainan, Zhejiang, and Guangdong. It is ...'', which is called "Jiangxiang" in Traditional Chinese medicine. References {{DEFAULTSORT:Trihydroxyflavone, 6,7,4'- Flavones ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aloe Emodin
Aloe emodin (1,8-dihydroxy-3-(hydroxymethyl)anthraquinone) is an anthraquinone and an isomer of emodin present in aloe latex, an exudate from the aloe plant. It has a strong stimulant-laxative action. Aloe emodin is not carcinogenic when applied to the skin, although it may increase the carcinogenicity of some kind of radiation. Aloe emodin is found in the gel, sap or leaves of aloe vera, the socotrine aloe, Barbados aloe, and Zanzibar aloes, the bark of ''Frangula'' (''Rhamnus frangula'') and cascara sagrada (''Rhamnus purshiana''), the leaves of Senna (''Cassia angustifolia''), and the rhizome of rhubarb (''Rheum rhaponticum ''Rheum rhaponticum'', the false rhubarb, rhapontic rhubarb or rhapontic, is a plant species in the genus '' Rheum'' found in the wild. It is the only ''Rheum'' species found only in Europe, and is now restricted to the Rila mountain range in sou ...''). Aloe-emodin has not been found in Natal aloes. References See also * Emodin {{Anthraqui ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thunberginol A
Thunberginol A is an isocoumarin found in '' Hydrangea macrophylla'' and the herbal preparation ''hydrangeae dulcis folium'' which is produced from its leaves. References Isocoumarins {{phenol-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
