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Bunyaviridae
''Bunyaviricetes'' is a class of segmented negative-strand RNA viruses with mainly tripartite genomes. Member viruses infect arthropods, plants, protozoans, and vertebrates. The name ''Bunyaviricetes'' derives from Bunyamwera, where the virus Bunyamwera virus was first discovered. Bunyaviruses belong to the fifth group of the Baltimore classification system, which includes viruses with a negative-sense, single-stranded RNA genome. They have an enveloped, spherical virion. Though generally found in arthropods or rodents, certain viruses in this class occasionally infect humans. Some of them also infect plants. In addition, there is a group of bunyaviruses whose replication is restricted to arthropods and is known as insect-specific bunyaviruses. A majority of bunyaviruses are vector-borne. With the exception of Hantaviruses and Arenaviruses, all viruses in the ''Bunyaviricetes'' class are transmitted by arthropods (mosquitos, tick, or sandfly). Hantaviruses are transmitted ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hantavirus
''Orthohantavirus'' is a genus of viruses that includes all hantaviruses (family ''Hantaviridae'') that cause disease in humans. Orthohantaviruses, hereafter referred to as hantaviruses, are naturally found primarily in rodents. In general, each hantavirus is carried by one rodent species and each rodent that carries a hantavirus carries one hantavirus species. Hantaviruses in their natural reservoirs usually cause an asymptomatic, persistent infection. In humans, however, hantaviruses cause two diseases: hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). HFRS is mainly caused by hantaviruses in Africa, Asia, and Europe, called Old World hantaviruses, and HPS is usually caused by hantaviruses in the Americas, called New World hantaviruses. Hantaviruses are transmitted mainly through aerosols and droplets that contain rodent excretions, as well as through contaminated food, bites, and scratches. Environmental factors such as rainfall, temperature, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bunyamwera Virus
Bunyamwera virus (BUNV) is a negative-sense, single-stranded enveloped RNA virus. It is assigned to the '' Orthobunyavirus'' genus, in the ''Peribunyaviridae'' family. Bunyamwera virus can infect both humans and ''Aedes aegypti'' (yellow fever mosquito). It is named for Bunyamwera, a town in western Uganda, where it was isolated in 1943. Reassortant viruses derived from Bunyamwera virus, such as Ngari virus, have been associated with large outbreaks of viral haemorrhagic fever in Kenya and Somalia. Molecular biology The genetic structure of Bunyamwera virus is typical for viruses in '' Bunyaviricetes'', which are a class of enveloped negative-sense, single-stranded RNA viruses with a genome split into three parts—Small (S), Middle (M), and Large (L). The L RNA segment encodes an RNA-dependent RNA polymerase (L protein), the M RNA segment encodes two surface glycoproteins (Gc and Gn) and a nonstructural protein (NSm), while the S RNA segment encodes a nucleocapsid pro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sense (molecular Biology)
In molecular biology and genetics, the sense of a nucleic acid molecule, particularly of a strand of DNA or RNA, refers to the nature of the roles of the strand and its complement in specifying a sequence of amino acids. Depending on the context, sense may have slightly different meanings. For example, the negative-sense strand of DNA is equivalent to the template strand, whereas the positive-sense strand is the non-template strand whose nucleotide sequence is equivalent to the sequence of the mRNA transcript. DNA sense Because of the complementary nature of base-pairing between nucleic acid polymers, a double-stranded DNA molecule will be composed of two strands with sequences that are reverse complements of each other. To help molecular biologists specifically identify each strand individually, the two strands are usually differentiated as the "sense" strand and the "antisense" strand. An individual strand of DNA is referred to as positive-sense (also positive (+) or simply se ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bunyamwera
Bunyamwera is a town in Bundibugyo District, Uganda. It lies just outside of Rwenzori Mountains National Park, which is to the south. The town is north of Kagugu, southeast of Bunyana, and southwest of Butama. Other nearby settlements include Bundimbuga, 1½ km north, and Bundikahondo, 2 km northwest. The peak of Busunga is 6 km northwest, Kyabwageya's peak is 10 km east, and Kinera's peak is 10 km east. The nearest hospital, Kasulenge Health Center II, is 9 km northeast. In the 1950s, Bunyamwera was considered a Konzo spur village, and children there went to primary school in the parish of Mutunda. Bunyamwera parish includes two hydropower plants, Ndugutu and Sindila. Bunyamwera is where '' Bunyamwera orthobunyavirus'' was first isolated, and it also lends its name to that virus' genus '' Orthobunyavirus'', its family ''Peribunyaviridae'', and its order ''Bunyavirales ''Bunyaviricetes'' is a class of segmented negative-strand RN ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Scandinavia
Scandinavia is a subregion#Europe, subregion of northern Europe, with strong historical, cultural, and linguistic ties between its constituent peoples. ''Scandinavia'' most commonly refers to Denmark, Norway, and Sweden. It can sometimes also refer to the Scandinavian Peninsula (which excludes Denmark but includes a part of northern Finland). In English usage, Scandinavia is sometimes used as a synonym for Nordic countries. Iceland and the Faroe Islands are sometimes included in Scandinavia for their Ethnolinguistics, ethnolinguistic relations with Sweden, Norway and Denmark. While Finland differs from other Nordic countries in this respect, some authors call it Scandinavian due to its economic and cultural similarities. The geography of the region is varied, from the Norwegian fjords in the west and Scandinavian mountains covering parts of Norway and Sweden, to the low and flat areas of Denmark in the south, as well as archipelagos and lakes in the east. Most of the population ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Finland
Finland, officially the Republic of Finland, is a Nordic country in Northern Europe. It borders Sweden to the northwest, Norway to the north, and Russia to the east, with the Gulf of Bothnia to the west and the Gulf of Finland to the south, opposite Estonia. Finland has a population of 5.6 million. Its capital and largest city is Helsinki. The majority of the population are Finns, ethnic Finns. The official languages are Finnish language, Finnish and Swedish language, Swedish; 84.1 percent of the population speak the first as their mother tongue and 5.1 percent the latter. Finland's climate varies from humid continental climate, humid continental in the south to boreal climate, boreal in the north. The land cover is predominantly boreal forest biome, with List of lakes of Finland, more than 180,000 recorded lakes. Finland was first settled around 9000 BC after the Last Glacial Period, last Ice Age. During the Stone Age, various cultures emerged, distinguished by differen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Russia
Russia, or the Russian Federation, is a country spanning Eastern Europe and North Asia. It is the list of countries and dependencies by area, largest country in the world, and extends across Time in Russia, eleven time zones, sharing Borders of Russia, land borders with fourteen countries. Russia is the List of European countries by population, most populous country in Europe and the List of countries and dependencies by population, ninth-most populous country in the world. It is a Urbanization by sovereign state, highly urbanised country, with sixteen of its urban areas having more than 1 million inhabitants. Moscow, the List of metropolitan areas in Europe, most populous metropolitan area in Europe, is the capital and List of cities and towns in Russia by population, largest city of Russia, while Saint Petersburg is its second-largest city and Society and culture in Saint Petersburg, cultural centre. Human settlement on the territory of modern Russia dates back to the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Puumala Virus
Puumala virus (PUUV) is the main cause of hemorrhagic fever with renal syndrome (HFRS) in Europe and Russia. Puumala virus is transmitted by the bank vole (''Clethrionomys glareolus''). In its natural reservoir, PUUV causes a persistent infection with few symptoms and is spread through excretions, fighting, and grooming. Humans can become infected by inhaling aerosols that contain rodent saliva, urine, or feces, as well as through bites and scratches. In humans, infection is usually asymptomatic but can lead to a mild form of HFRS often called nephropathia epidemica (NE). Symptoms include fever and headache, impaired vision, as well as the appearance of spots on the skin and renal symptoms such as kidney swelling, excess protein in urine, blood in urine, decreased urine production, and kidney failure. The case fatality rate from infection is less than 1%. The genome of PUUV is about 12 kilobases (kb) in length and segmented into three negative-sense, single-stranded RNA (-ssRNA) ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Viremia
Viremia is a medical condition where viruses enter the bloodstream and hence have access to the rest of the body. It is similar to ''bacteremia'', a condition where bacteria enter the bloodstream. The name comes from combining the word "virus" with the Greek word for "blood" (''haima''). It usually lasts for 4 to 5 days in the primary condition. Primary versus secondary Primary viremia refers to the initial spread of virus in the blood from the first site of infection. Secondary viremia occurs when primary viremia has resulted in infection of additional tissues via bloodstream, in which the virus has replicated and once more entered the circulation. Usually secondary viremia results in higher viral shedding and viral loads within the bloodstream due to the possibility that the virus is able to reach its natural host cell from the bloodstream and replicate more efficiently than the initial site. An excellent example to profile this distinction is the rabies virus. Usually the vir ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
