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Brodmann Area 30
Brodmann area 30, also known as agranular retrolimbic area 30, is a subdivision of the cytoarchitecturally defined retrosplenial region of the cerebral cortex. In the human it is located in the isthmus of cingulate gyrus. Cytoarchitecturally it is bounded internally by the granular retrolimbic area 29, dorsally by the ventral posterior cingulate area 23 and ventrolaterally by the ectorhinal area 36 (Brodmann-1909). In primates, Brodmann area 30 demonstrates projections to the mid-dorsolateral prefrontal cortex ( Brodmann areas 46 and 9) and the thalamus. Additionally, approximately 20% of cortical inputs to the entorhinal cortex arise from the retrosplenial cortex. Individuals with lesions to retrosplenial cortex, predominately Brodmann’s area 30, demonstrate dysfunction in their topographical orientation, including defective navigation in novel and familiar environments. See also * Brodmann area A Brodmann area is a region of the cerebral cortex, in the human or ...
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Cytoarchitecture
Cytoarchitecture (from Greek κύτος 'cell' and ἀρχιτεκτονική 'architecture'), also known as cytoarchitectonics, is the study of the cellular composition of the central nervous system's tissues under the microscope. Cytoarchitectonics is one of the ways to parse the brain, by obtaining sections of the brain using a microtome and staining them with chemical agents which reveal where different neurons are located. The study of the parcellation of ''nerve fibers'' (primarily axons) into layers forms the subject of myeloarchitectonics (from Greek μυελός 'marrow' and ἀρχιτεκτονική 'architecture'), an approach complementary to cytoarchitectonics. History of the cerebral cytoarchitecture Defining cerebral cytoarchitecture began with the advent of histology—the science of slicing and staining brain slices for examination. It is credited to the Viennese psychiatrist Theodor Meynert (1833–1892), who in 1867 noticed regional variations in the ...
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Retrosplenial Region
The retrosplenial cortex (RSC) is a cortical area in the brain comprising Brodmann areas 29 and 30. It is secondary association cortex, making connections with numerous other brain regions. The region's name refers to its anatomical location immediately behind the splenium of the corpus callosum in primates, although in rodents it is located more towards the brain surface and is relatively larger. Its function is currently not well understood, but its location close to visual areas and also to the hippocampal spatial/memory system suggest it may have a role in mediating between perceptual and memory functions, particularly in the spatial domain. However, its exact contribution to either space or memory processing has been hard to pin down. Anatomy There is large variation in the region's size across different species. In humans it comprises roughly 0.3% of the entire cortical surface whereas in rabbits it is at least 10% and in rats it extends for more than half the cerebrum d ...
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Cerebral Cortex
The cerebral cortex, also known as the cerebral mantle, is the outer layer of neural tissue of the cerebrum of the brain in humans and other mammals. It is the largest site of Neuron, neural integration in the central nervous system, and plays a key role in attention, perception, awareness, thought, memory, language, and consciousness. The six-layered neocortex makes up approximately 90% of the Cortex (anatomy), cortex, with the allocortex making up the remainder. The cortex is divided into left and right parts by the longitudinal fissure, which separates the two cerebral hemispheres that are joined beneath the cortex by the corpus callosum and other commissural fibers. In most mammals, apart from small mammals that have small brains, the cerebral cortex is folded, providing a greater surface area in the confined volume of the neurocranium, cranium. Apart from minimising brain and cranial volume, gyrification, cortical folding is crucial for the Neural circuit, brain circuitry ...
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Isthmus Of Cingulate Gyrus
The cingulate gyrus commences below the rostrum of the corpus callosum, curves around in front of the genu, extends along the upper surface of the body, and finally turns downward behind the splenium, where it is connected by a narrow isthmus with the parahippocampal gyrus The parahippocampal gyrus (or hippocampal gyrus') is a grey matter cortical region, a gyrus of the brain that surrounds the hippocampus and is part of the limbic system. The region plays an important role in memory encoding and retrieval. It ha .... Additional images File:Medial surface of cerebral cortex - gyri.png, Medial surface of cerebral cortex - gyri File:Isthmus_Cingulate_-_DK_ATLAS.png, Isthmus of the cingulate gyrus, medial surface of right hemisphere References External links * http://braininfo.rprc.washington.edu/whereisit.aspx?language=0&requestID=ID163&parentID=ID159&originalID=ID163 * https://web.archive.org/web/20091029114245/http://bstr431.biostr.washington.edu/syl/lab7/lab7.htm ...
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Granular Retrolimbic Area 29
Brodmann area 29, also known as granular retrolimbic area 29 or granular retrosplenial cortex, is a cytoarchitecturally defined portion of the retrosplenial region of the cerebral cortex. In the human it is a narrow band located in the isthmus of cingulate gyrus. Cytoarchitecturally it is bounded internally by the ectosplenial area 26 and externally by the agranular retrolimbic area 30 (Brodmann-1909). Brodmann has this to say about area 29, amongst his other comments on it: "An unusual regression of layer II together with layer III is found in the granular retrosplenial cortex, illustrated in Figures 38 to 41 for four different animals. Here, in addition to the regression of layers II and III, there is fusion of the original layers V and VI and at the same time an isolated massive increase of the inner granular layer, that is particularly prominent in Figures 38 and 39;..." See also * Brodmann area * Retrosplenial region The retrosplenial cortex (RSC) is a cortical area i ...
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Ventral Posterior Cingulate Area 23
Brodmann area 23 (BA23) is a region in the brain that lies inside the posterior cingulate cortex. It lies between Brodmann area 30 and Brodmann area 31 and is located on the medial wall of the cingulate gyrus between the callosal sulcus and the cingulate sulcus. Human This area is also known as ventral posterior cingulate area 23. It is a subdivision of the cytoarchitecturally defined cingulate region of cerebral cortex. In the human it occupies most of the posterior cingulate gyrus adjacent to the corpus callosum. At the caudal extreme it is bounded approximately by the parieto-occipital sulcus. Cytoarchitecturally it is bounded dorsally by the dorsal posterior cingulate area 31, rostrally by the ventral anterior cingulate area 24, and ventrorostrally in its caudal half by the retrosplenial region (Brodmann-1909). Guenon Brodmann area 23 is a subdivision of the cerebral cortex of the guenon defined on the basis of cytoarchitecture. Brodmann regarded it as topographically and ...
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Ectorhinal Area 36
Brodmann area 35, together with Brodmann area 36, comprise the perirhinal cortex. They are cytoarchitecturally defined temporal regions of the cerebral cortex. Human Brodmann area 35 This area is known as perirhinal area 35. It is a subdivision of the cytoarchitecturally defined hippocampal region of the cerebral cortex. In the human it is located along the rhinal sulcus. Cytoarchitectually it is bounded medially by the entorhinal area 28 and laterally by the ectorhinal area 36 (H). Monkey Brodmann area 35 Brodmann found a cytoarchitecturally homologous area in the monkey (Cercopithecus), but it was so weakly developed that he omitted it from the cortical map of that species (Brodmann-1909). Brodmann area 36 With its medial boundary corresponding approximately to the rhinal sulcus it is located primarily in the fusiform gyrus. Cytoarchitecturally it is bounded laterally and caudally by the inferior temporal area 20, medially by the area 35 and rostrally by the temporo ...
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Brodmann Area 46
Brodmann area 46, or BA46, is part of the frontal cortex in the human brain. It is between BA10 and BA45. BA46 is known as middle frontal area 46. In the human brain it occupies approximately the middle third of the middle frontal gyrus and the most rostral portion of the inferior frontal gyrus. Brodmann area 46 roughly corresponds with the dorsolateral prefrontal cortex (DLPFC), although the borders of area 46 are based on cytoarchitecture rather than function. The DLPFC also encompasses part of granular frontal area 9, directly adjacent on the dorsal surface of the cortex. Cytoarchitecturally, BA46 is bounded dorsally by the granular frontal area 9, rostroventrally by the frontopolar area 10 and caudally by the triangular area 45 (Brodmann-1909). There is some discrepancy between the extent of BA8 (Brodmann-1905) and the same area as described by Walker (1940). Function The dorsolateral prefrontal cortex plays a central role in sustaining attention and managing wor ...
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Brodmann Area 9
Brodmann area 9, or BA9, refers to a cytoarchitecturally defined portion of the frontal cortex in the brain of humans and other primates. Its cytoarchitecture is referred to as granular due to the concentration of granule cells in layer IV. It contributes to the dorsolateral and medial prefrontal cortex. Functions The area is involved in short term memory, evaluating recency, overriding automatic responses, verbal fluency, error detection, auditory verbal attention, inferring the intention of others, inferring deduction from spatial imagery, inductive reasoning, attributing intention, sustained attention involved in counting a series of auditory stimuli, and displays lower levels of energy consumption in individuals suffering from bipolar disorder. The area found on the left hemisphere is at least partially responsible for working memory, empathy, idioms, processing pleasant and unpleasant emotional scenes, self criticisms and attention to negative emotions. On the right he ...
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Entorhinal Cortex
The entorhinal cortex (EC) is an area of the brain's allocortex, located in the medial temporal lobe, whose functions include being a widespread network hub for memory, navigation, and the perception of time.Integrating time from experience in the lateral entorhinal cortex Albert Tsao, Jørgen Sugar, Li Lu, Cheng Wang, James J. Knierim, May-Britt Moser & Edvard I. Moser Naturevolume 561, pages57–62 (2018) The EC is the main interface between the hippocampus and neocortex. The EC-hippocampus system plays an important role in declarative (autobiographical/episodic/semantic) memories and in particular spatial memories including memory formation, memory consolidation, and memory optimization in sleep. The EC is also responsible for the pre-processing (familiarity) of the input signals in the reflex nictitating membrane response of classical trace conditioning; the association of impulses from the eye and the ear occurs in the entorhinal cortex. Anatomy The entorhina ...
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Retrosplenial Cortex
The retrosplenial cortex (RSC) is a cortical area in the brain comprising Brodmann areas 29 and 30. It is secondary association cortex, making connections with numerous other brain regions. The region's name refers to its anatomical location immediately behind the splenium of the corpus callosum in primates, although in rodents it is located more towards the brain surface and is relatively larger. Its function is currently not well understood, but its location close to visual areas and also to the hippocampal spatial/memory system suggest it may have a role in mediating between perceptual and memory functions, particularly in the spatial domain. However, its exact contribution to either space or memory processing has been hard to pin down. Anatomy There is large variation in the region's size across different species. In humans it comprises roughly 0.3% of the entire cortical surface whereas in rabbits it is at least 10% and in rats it extends for more than half the cerebrum do ...
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Brodmann Area
A Brodmann area is a region of the cerebral cortex, in the human or other primate brain, defined by its cytoarchitecture, or histological structure and organization of cells. The concept was first introduced by the German anatomist Korbinian Brodmann in the early 20th century. Brodmann mapped the human brain based on the varied cellular structure across the cortex and identified 52 distinct regions, which he numbered 1 to 52. These regions, or Brodmann areas, correspond with diverse functions including sensation, motor control, and cognition. History Brodmann areas were originally defined and numbered by the German anatomist Korbinian Brodmann based on the cytoarchitectural organization of neurons he observed in the cerebral cortex using the Nissl method of cell staining. Brodmann published his maps of cortical areas in humans, monkeys, and other species in 1909, along with many other findings and observations regarding the general cell types and laminar organization of t ...
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