Arvid Afzelius
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Arvid Afzelius
Arvid Afzelius (1857–1923) was a Swedish dermatologist. As a student at the Karolinska institutet, Afzelius studied under the prominent dermatologist Moritz Kaposi (1837–1902) in Vienna. Kaposi has now become a household name because "his" sarcoma is a common lesion in the acquired immunodeficiency syndrome. In a 1909 meeting of the Swedish Society of Dermatology, Arvid Afzelius presented research about an expanding, ring like lesion he had observed. Afzelius published his work 12 years later and speculated that the rash came from the bite of an Ixodes tick. This rash, now known as erythema migrans, is an early indication of Lyme disease. Borrelia afzelii, one of the Borrelia ''Borrelia'' is a genus of bacteria of the spirochete phylum. Several species cause Lyme disease, also called Lyme borreliosis, a zoonotic, vector-borne disease transmitted by ticks. Other species of ''Borrelia'' cause relapsing fever, and are t ... species that is an agent of Lyme disease, is name ...
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Dermatologist
Dermatology is the branch of medicine dealing with the skin.''Random House Webster's Unabridged Dictionary.'' Random House, Inc. 2001. Page 537. . It is a speciality with both medical and surgical aspects. A dermatologist is a specialist medical doctor who manages diseases related to skin, hair, nails, and some cosmetic problems. Etymology Attested in English in 1819, the word "dermatology" derives from the Greek δέρματος (''dermatos''), genitive of δέρμα (''derma''), "skin" (itself from δέρω ''dero'', "to flay") and -λογία ''-logia''. Neo-Latin ''dermatologia'' was coined in 1630, an anatomical term with various French and German uses attested from the 1730s. History In 1708, the first great school of dermatology became a reality at the famous Hôpital Saint-Louis in Paris, and the first textbooks (Willan's, 1798–1808) and atlases ( Alibert's, 1806–1816) appeared in print around the same time.Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in ...
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Tick
Ticks (order Ixodida) are parasitic arachnids that are part of the mite superorder Parasitiformes. Adult ticks are approximately 3 to 5 mm in length depending on age, sex, species, and "fullness". Ticks are external parasites, living by feeding on the blood of mammals, birds, and sometimes reptiles and amphibians. The timing of the origin of ticks is uncertain, though the oldest known tick fossils are from the Cretaceous period, around 100 million years old. Ticks are widely distributed around the world, especially in warm, humid climates. Ticks belong to two major families, the Ixodidae or hard ticks, and the Argasidae, or soft ticks. ''Nuttalliella,'' a genus of tick from southern Africa is the only member of the family Nuttalliellidae, and represents the most primitive living lineage of ticks. Adults have ovoid/pear-shaped bodies (idiosomas) which become engorged with blood when they feed, and eight legs. Their cephalothorax and abdomen are completely fused. In addit ...
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1923 Deaths
Nineteen or 19 may refer to: * 19 (number), the natural number following 18 and preceding 20 * one of the years 19 BC, AD 19, 1919, 2019 Films * ''19'' (film), a 2001 Japanese film * ''Nineteen'' (film), a 1987 science fiction film Music * 19 (band), a Japanese pop music duo Albums * ''19'' (Adele album), 2008 * ''19'', a 2003 album by Alsou * ''19'', a 2006 album by Evan Yo * ''19'', a 2018 album by MHD * ''19'', one half of the double album ''63/19'' by Kool A.D. * '' Number Nineteen'', a 1971 album by American jazz pianist Mal Waldron * ''XIX'' (EP), a 2019 EP by 1the9 Songs * "19" (song), a 1985 song by British musician Paul Hardcastle. * "Nineteen", a song by Bad4Good from the 1992 album ''Refugee'' * "Nineteen", a song by Karma to Burn from the 2001 album ''Almost Heathen''. * "Nineteen" (song), a 2007 song by American singer Billy Ray Cyrus. * "Nineteen", a song by Tegan and Sara from the 2007 album '' The Con''. * "XIX" (song), a 2014 song by Sl ...
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1857 Births
Events January–March * January 1 – The biggest Estonian newspaper, '' Postimees'', is established by Johann Voldemar Jannsen. * January 7 – The partly French-owned London General Omnibus Company begins operating. * January 9 – The 7.9 Fort Tejon earthquake shakes Central and Southern California, with a maximum Mercalli intensity of IX (''Violent''). * January 24 – The University of Calcutta is established in Calcutta, as the first multidisciplinary modern university in South Asia. The University of Bombay is also established in Bombay, British India, this year. * February 3 – The National Deaf Mute College (later renamed Gallaudet University) is established in Washington, D.C., becoming the first school for the advanced education of the deaf. * February 5 – The Federal Constitution of the United Mexican States is promulgated. * March – The Austrian garrison leaves Bucharest. * March 3 ** France and the United Kingdom ...
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Borrelia
''Borrelia'' is a genus of bacteria of the spirochete phylum. Several species cause Lyme disease, also called Lyme borreliosis, a zoonotic, vector-borne disease transmitted by ticks. Other species of ''Borrelia'' cause relapsing fever, and are transmitted by ticks or lice, depending on the species of bacteria. A few ''Borrelia'' species as ''Candidatus'' Borrelia mahuryensis harbor intermediate genetic features between Lyme disease and relapsing fever ''Borrelia''. The genus is named after French biologist Amédée Borrel (1867–1936), who first documented the distinction between a species of ''Borrelia'', ''B. anserina'', and the other known type of spirochete at the time, ''Treponema pallidum''. This bacterium must be viewed using dark-field microscopy, which make the cells appear white against a dark background. ''Borrelia'' species are grown in Barbour-Stoenner-Kelly medium. Of 52 known species of ''Borrelia'', 20 are members of the Lyme disease group (with an additional 3 ...
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Lyme Disease Microbiology
Lyme disease, or borreliosis, is caused by spirochetal bacteria from the genus '' Borrelia'', which has 52 known species. Three main species (''Borrelia garinii'', ''Borrelia afzelii'', and ''Borrelia burgdorferi s.s.'') are the main causative agents of the disease in humans, while a number of others have been implicated as possibly pathogenic. ''Borrelia'' species in the species complex known to cause Lyme disease are collectively called ''Borrelia burgdorferi'' ''sensu lato'' (''s.l.'') not to be confused with the single species in that complex '' Borrelia burgdorferi sensu stricto'' which is responsible for nearly all cases of Lyme disease in North America. ''Borrelia'' are microaerophilic and slow-growing—the primary reason for the long delays when diagnosing Lyme disease have been found to have greater strain diversity than previously estimated. The strains differ in clinical symptoms and/or presentation as well as geographic distribution. Except for '' Borrelia recurren ...
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Lyme Disease
Lyme disease, also known as Lyme borreliosis, is a vector-borne disease caused by the ''Borrelia'' bacterium, which is spread by ticks in the genus ''Ixodes''. The most common sign of infection is an expanding red rash, known as erythema migrans (EM), which appears at the site of the tick bite about a week afterwards. The rash is typically neither itchy nor painful. Approximately 70–80% of infected people develop a rash. Early diagnosis can be difficult. Other early symptoms may include fever, headaches and tiredness. If untreated, symptoms may include loss of the ability to move one or both sides of the face, joint pains, severe headaches with neck stiffness or heart palpitations. Months to years later repeated episodes of joint pain and swelling may occur. Occasionally shooting pains or tingling in the arms and legs may develop. Despite appropriate treatment about 10 to 20% of those affected develop joint pains, memory problems and tiredness for at least six months. Lym ...
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Erythema Migrans
Erythema migrans or erythema chronicum migrans is an expanding rash often seen in the early stage of Lyme disease, and can also (but less commonly) be caused by southern tick-associated rash illness (STARI). Page last reviewed: October 22, 2015 It can appear anywhere from one day to one month after a tick bite. This rash does not represent an allergic reaction to the bite, but rather an actual skin infection of one of the Lyme bacteria species from the genus ''Borrelia''. The rash's name comes from New Latin for "migrating redness". Lyme disease "Erythema migrans is the only manifestation of Lyme disease in the United States that is sufficiently distinctive to allow clinical diagnosis in the absence of laboratory confirmation." Often, but not always, mentions of a target lesion (bull's-eye lesion) are talking about erythema migrans. However, the appearance of erythema migrans can vary considerably: while some look like a bull's eye, in the U.S. most are evenly red or bluish, ...
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Ixodes
''Ixodes'' is a genus of hard-bodied ticks (family Ixodidae). It includes important disease vectors of animals and humans ( tick-borne disease), and some species (notably '' Ixodes holocyclus'') inject toxins that can cause paralysis. Some ticks in this genus may transmit the pathogenic bacterium '' Borrelia burgdorferi'' responsible for causing Lyme disease. Additional organisms that may be transmitted by ''Ixodes'' are parasites from the genus ''Babesia'', which cause babesiosis, and bacteria from the related genus ''Anaplasma'', which cause anaplasmosis. Species These species are recognised within the genus ''Ixodes'': *''Ixodes abrocomae'' Lahille, 1917 *''Ixodes acer'' Apanaskevich & Schenk, 2020 *''Ixodes acuminatus'' Neumann, 1901 *''Ixodes acutitarsus'' (Karsch, 1880) *''Ixodes affinis'' Neumann, 1899 *''Ixodes albignaci'' Uilenberg & Hoogstraal, 1969 *'' Ixodes alluaudi'' Neumann, 1913 *''Ixodes amarali'' Fonseca, 1935 *'' Ixodes amersoni'' Kohls, 1966 *''Ixodes ...
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Swedes
Swedes ( sv, svenskar) are a North Germanic ethnic group native to the Nordic region, primarily their nation state of Sweden, who share a common ancestry, culture, history and language. They mostly inhabit Sweden and the other Nordic countries, in particular Finland where they are an officially recognized minority, with a substantial diaspora in other countries, especially the United States. Etymology The English term "Swede" has been attested in English since the late 16th century and is of Middle Dutch or Middle Low German origin. In Swedish, the term is ''svensk'', which is from the name of '' svear'' (or Swedes), the people who inhabited Svealand in eastern central Sweden, and were listed as ''Suiones'' in Tacitus' history '' Germania'' from the first century AD. The term is believed to have been derived from the Proto-Indo-European reflexive pronominal root, , as the Latin ''suus''. The word must have meant "one's own (tribesmen)". The same root and original ...
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Rash
A rash is a change of the human skin which affects its color, appearance, or texture. A rash may be localized in one part of the body, or affect all the skin. Rashes may cause the skin to change color, itch, become warm, bumpy, chapped, dry, cracked or blistered, swell, and may be painful. The causes, and therefore treatments for rashes, vary widely. Diagnosis must take into account such things as the appearance of the rash, other symptoms, what the patient may have been exposed to, occupation, and occurrence in family members. The diagnosis may confirm any number of conditions. The presence of a rash may aid diagnosis; associated signs and symptoms are diagnostic of certain diseases. For example, the rash in measles is an erythematous, morbilliform, maculopapular rash that begins a few days after the fever starts. It classically starts at the head, and spreads downwards. Differential diagnosis Common causes of rashes include: * Food allergy * Medication side effects * An ...
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Sarcoma
A sarcoma is a malignant tumor, a type of cancer that arises from transformed cells of mesenchymal ( connective tissue) origin. Connective tissue is a broad term that includes bone, cartilage, fat, vascular, or hematopoietic tissues, and sarcomas can arise in any of these types of tissues. As a result, there are many subtypes of sarcoma, which are classified based on the specific tissue and type of cell from which the tumor originates. Sarcomas are ''primary'' connective tissue tumors, meaning that they arise in connective tissues. This is in contrast to ''secondary'' (or "metastatic") connective tissue tumors, which occur when a cancer from elsewhere in the body (such as the lungs, breast tissue or prostate) spreads to the connective tissue. The word ''sarcoma'' is derived from the Greek σάρκωμα ''sarkōma'' "fleshy excrescence or substance", itself from σάρξ ''sarx'' meaning "flesh". Classification Sarcomas are typically divided into two major groups: bone sar ...
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