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Addiction Research Center
The Addiction Research Center (ARC) is a center of addiction research that was founded in 1935. It was originally based in Lexington, Kentucky, United States, housed on the rural campus of the US Public Health Service Hospital. The ARC shared the campus with the Federal Bureau of Prisons; subjects ("volunteers") for the human experimental research were drawn from a pool of felons convicted of drug charges. Dr Harris Isbell was the Director of Research from 1945 until 1963. The ARC became part of the National Institute on Drug Abuse The National Institute on Drug Abuse (NIDA) is a United States federal government research institute whose mission is to "advance science on the causes and consequences of drug use and addiction and to apply that knowledge to improve individual a ... in 1974. The ARC clinical research unit and basic science unit were relocated to Baltimore, Maryland in 1979 and 1984, respectively. Research at the ARC is well-documented in two books published in 1978, ...
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Lexington, Kentucky
Lexington is a city in Kentucky, United States that is the county seat of Fayette County. By population, it is the second-largest city in Kentucky and 57th-largest city in the United States. By land area, it is the country's 28th-largest city. The city is also known as "Horse Capital of the World". It is within the state's Bluegrass region. Notable locations in the city include the Kentucky Horse Park, The Red Mile and Keeneland race courses, Rupp Arena, Central Bank Center, Transylvania University, the University of Kentucky, and Bluegrass Community and Technical College. As of the 2020 census the population was 322,570, anchoring a metropolitan area of 516,811 people and a combined statistical area of 747,919 people. Lexington is consolidated entirely within Fayette County, and vice versa. It has a nonpartisan mayor-council form of government, with 12 council districts and three members elected at large, with the highest vote-getter designated vice mayor. His ...
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United States
The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country Continental United States, primarily located in North America. It consists of 50 U.S. state, states, a Washington, D.C., federal district, five major unincorporated territories, nine United States Minor Outlying Islands, Minor Outlying Islands, and 326 Indian reservations. The United States is also in Compact of Free Association, free association with three Oceania, Pacific Island Sovereign state, sovereign states: the Federated States of Micronesia, the Marshall Islands, and the Palau, Republic of Palau. It is the world's List of countries and dependencies by area, third-largest country by both land and total area. It shares land borders Canada–United States border, with Canada to its north and Mexico–United States border, with Mexico to its south and has maritime borders with the Bahamas, Cuba, Russia, and other nations. With a population of over 333 m ...
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Federal Medical Center, Lexington
The Federal Medical Center, Lexington (FMC Lexington) is a United States federal prison in Kentucky for male or female inmates requiring medical or mental health care. It is designated as an administrative facility, which means that it holds inmates of all security classifications. It is operated by the Federal Bureau of Prisons, a division of the United States Department of Justice. The facility also has an adjacent minimum-security satellite camp for female inmates. FMC Lexington is located 7 miles (11 km) north of Lexington and 20 miles (32 km) southeast of Frankfort, the state capital. History The site opened on May 15, 1935 on under the name "United States Narcotic Farm" then changed shortly after to " U.S. Public Health Service Hospital." In 1967, it changed its name again to "National Institute of Mental Health, Clinical Research Center." Its original purpose was to treat people who "voluntarily" were admitted with drug abuse problems and treat them, with mostl ...
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Federal Bureau Of Prisons
The Federal Bureau of Prisons (BOP) is a United States federal law enforcement agency under the Department of Justice that is responsible for the care, custody, and control of incarcerated individuals who have committed federal crimes; that is, violations of the United States Code. History The federal prison system had existed for more than 30 years before the BOP was established. Although its wardens functioned almost autonomously, the Superintendent of Prisons, a Department of Justice official in Washington, was nominally in charge of federal prisons. The passage of the "Three Prisons Act" in 1891 authorized the first three federal penitentiaries: USP Leavenworth, USP Atlanta, and USP McNeil Island with limited supervision by the Department of Justice. Until 1907, prison matters were handled by the Justice Department General Agent, with responsibility for Justice Department accounts, oversight of internal operations, and certain criminal investigations, as well as priso ...
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Harris Isbell
Harris Isbell (June 7, 1910 – December 23, 1994) was an American pharmacologist and the director of research for the NIMH Addiction Research Center at the Public Health Service Hospital in Lexington, Kentucky from 1945 to 1963. He did extensive research on the physical and psychological effects of various drugs on humans (imprisoned narcotics offenders, see below). Early work investigated aspects of physical dependence (an important aspect of drug addiction) with opiates and barbiturates, while later work (at least partially funded by the Central Intelligence Agency as part of the MKUltra project)Marks JD. 1991. ''The Search for the "Manchurian Candidate"''. W.W. Norton.Lee, MA. 1994. ''Acid Dreams: The Complete Social History of LSD''. Grove Press.Campbell ND, Olsen JP, Walden L. 2008. ''The Narcotics Farm''. Harry N. Abrams. investigated psychedelic drugs, including LSD. The research was extensively reported in academic journals such as the ''Journal of Pharmacology and Exp ...
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National Institute On Drug Abuse
The National Institute on Drug Abuse (NIDA) is a United States federal government research institute whose mission is to "advance science on the causes and consequences of drug use and addiction and to apply that knowledge to improve individual and public health." The institute has conducted an in-depth study of addiction according to its biological, behavioral and social components. It has also supported many treatments such as nicotine patches and gums, and performed research into AIDS and other drug-related diseases. Its monopoly on the supply of research-grade marijuana has proved controversial. History NIDA's roots can be traced back to 1935, when a research facility (named the Addiction Research Center in 1948) was established in Lexington, Kentucky as part of a USPHS hospital. The Drug Abuse Warning Network (DAWN) and National Household Survey on Drug Abuse (NHSDA) were created in 1972. In 1974 NIDA was established as part of the Alcohol, Drug Abuse, and Mental Health A ...
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Addiction Organizations In The United States
Addiction is a neuropsychological disorder characterized by a persistent and intense urge to engage in certain behaviors, one of which is the usage of a drug, despite substantial harm and other negative consequences. Repetitive drug use often alters brain function in ways that perpetuate craving, and weakens (but does not completely negate) self-control. This phenomenon – drugs reshaping brain function – has led to an understanding of addiction as a brain disorder with a complex variety of psychosocial as well as neurobiological (and thus involuntary) factors that are implicated in addiction's development. Classic signs of addiction include compulsive engagement in rewarding stimuli, ''preoccupation'' with substances or behavior, and continued use despite negative consequences. Habits and patterns associated with addiction are typically characterized by immediate gratification (short-term reward), coupled with delayed deleterious effects (long-term costs). Examples ...
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Lysergic Acid Diethylamide
Lysergic acid diethylamide (LSD), also known colloquially as acid, is a potent psychedelic drug. Effects typically include intensified thoughts, emotions, and sensory perception. At sufficiently high dosages LSD manifests primarily mental, visual, as well as auditory, hallucinations. Dilated pupils, increased blood pressure, and increased body temperature are typical. Effects typically begin within half an hour and can last for up to 20 hours. LSD is also capable of causing mystical experiences and ego dissolution. It is used mainly as a recreational drug or for spiritual reasons. LSD is both the prototypical psychedelic and one of the "classical" psychedelics, being the psychedelics with the greatest scientific and cultural significance. LSD is typically either swallowed or held under the tongue. It is most often sold on blotter paper and less commonly as tablets, in a watery solution or in gelatin squares called panes. LSD is considered to be non-addictive with low potent ...
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