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A5 and variants may refer to: Science and mathematics * A5 regulatory sequence in biochemistry * A5, the abbreviation for the androgen Androstenediol * Annexin A5, a human cellular protein * ATC code A05 ''Bile and liver therapy'', a subgroup of the Anatomical Therapeutic Chemical Classification System * British NVC community A5 (Ceratophyllum demersum community), a British Isles plants community * Subfamily A5, a Rhodopsin-like receptors subfamily * Noradrenergic cell group A5, a noradrenergic cell group located in the Pons * A5 pod, a name given to a group of orcas (Orcinus orca) found off the coast of British Columbia, Canada * A5, the strain at fracture of a material as measured with a load test on a cylindrical body of length 5 times its diameter * ''A''5, the alternating group on five elements Technology * Apple A5 The Apple A5 is a 32-bit system on a chip (SoC) designed by Apple Inc. and manufactured by Samsung. The first product Apple featured an A5 in was the iPa ...
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A5 Regulatory Sequence
Transcription (biology), Transcription of insulin is regulated by the binding of various transcription factors to the ~400 base pairs before the insulin transcription start site, called the "insulin regulatory sequence". This sequence is made up of several distinct regions with different biochemical properties, each of which serve as binding sites for distinct regulatory proteins. First, multiple adenosine, A/Thymidine, T-rich sequences, called "A elements", each of which contains a "TAAT" reocognized by homeodomain proteins. These regions are primarily bound by PDX-1, but also Cdx2 and Isl-1. Second, two so-called "C elements" – C1 located 107–118 base pairs before the transcription start site; C2 311–317 base pairs before the start site. C1 is bound by RIPE3b1 via MafA. C2 (also called the "pancreatic islet cell enhancer sequence" or "PISCES") is bound by PAX6. Third, an "E element" (two in rodents) with sequence GCCATCTG is 91–100 base pairs before the transcription start s ...
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