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Albert C. Broders
Albert Compton Broders (August 8, 1885 – March 27, 1964) was an American surgical pathologist best known for developing the numerical tumor grading system, which evaluates cancer prognosis based on cellular differentiation. His work laid the foundation for modern cancer staging and personalized oncology. Early life and education Broders was born in Fairfax County, Virginia, on August 8, 1885. He attended Potomac Academy in Alexandria, Virginia. He enrolled at the Medical College of Virginia (MCV), where he earned his medical degree in 1910. He completed a one-year Internship (medicine), internship at Charlotte Williams Memorial Hospital in Richmond, Virginia, intending to become a surgeon. However, his interest shifted to surgical pathology after spending extensive time studying excised Laboratory specimen, specimens. Following the internship, Broders became an assistant to Charles R. Robins at , assisting in surgeries, administering anesthesia, and examining pathological specime ...
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Surgical Pathologist
Surgical pathology is the most significant and time-consuming area of practice for most anatomical pathology, anatomical pathologists. Surgical pathology involves gross and microscopic examination of surgery, surgical specimens, as well as biopsy, biopsies submitted by surgeons and non-surgeons such as internal medicine, general internists, medical subspecialists, dermatologists, and interventional radiologists. The practice of surgical pathology allows for definitive diagnosis of disease (or lack thereof) in any case where tissue is surgically removed from a patient. This is usually performed by a combination of gross (i.e., macroscopic) and histology, histologic (i.e., microscopic) examination of the tissue, and may involve evaluations of molecular properties of the tissue by immunohistochemistry or other laboratory tests. Specimens There are two major types of specimens submitted for surgical pathology analysis: ''biopsy, biopsies'' and ''surgical resections.'' A ''biopsy'' ...
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Johns Hopkins Hospital
Johns Hopkins Hospital (JHH) is the teaching hospital and biomedical research facility of Johns Hopkins School of Medicine in Baltimore, Maryland. Founded in 1889, Johns Hopkins Hospital and its school of medicine are considered to be the founding institutions of modern American medicine and the birthplace of numerous famed medical traditions, including rounds, residents, and house staff. Several medical specialties were founded at the hospital, including neurosurgery by Harvey Cushing and Walter Dandy, cardiac surgery by Alfred Blalock and Vivien Thomas, and child psychiatry by Leo Kanner. Johns Hopkins Children's Center, which serves infants, children, teens, and young adults aged 0–21, is attached to the hospital. Johns Hopkins Hospital is widely regarded as one of the world's greatest hospitals and medical institutions. For 21 consecutive years from 1991 to 2020, it was ranked as the best overall hospital in the United States by ''U.S. News & World Report''. In its 2019–20 ...
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Cancer Treatment
Cancer treatments are a wide range of treatments available for the many different types of cancer, with each cancer type needing its own specific treatment. Treatments can include surgery, chemotherapy, radiation therapy, hormonal therapy, targeted therapy including small-molecule drugs or monoclonal antibodies, and PARP inhibitors such as olaparib. Other therapies include hyperthermia, immunotherapy, photodynamic therapy, and stem-cell therapy. Most commonly cancer treatment involves a series of separate therapies such as chemotherapy before surgery. Angiogenesis inhibitors are sometimes used to enhance the effects of immunotherapies. The choice of therapy depends upon the location and grade of the tumor and the stage of the disease, as well as the general state of the patient. Biomarker testing can help to determine the type of cancer, and indicate the best therapy. A number of experimental cancer treatments are continuously under development. In 2023 it was estim ...
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Cancer (journal)
''Cancer'' is a biweekly peer-reviewed scientific journal covering oncology. The journal was established in 1948. It is an official journal of the American Cancer Society and is published by Wiley-Blackwell on behalf of the society. The first editor-in-chief was Fred W. Stewart, who held that position until 1961. The current editor-in-chief is Suresh S. Ramalingam, and the previous one was Fadlo R. Khuri. '' Cancer Cytopathology'' was published as a section from 1997 until 2008, when it was split into a separate journal. Abstracting and indexing The journal is abstracted and indexed in: According to the ''Journal Citation Reports'', the journal has a 2015 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a type of journal ranking. Journals with higher impact factor values are considered more prestigious or important within their field. The Impact Factor of a journa ... of 5.649, ranking it 26th out of 211 journals in the categ ...
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Journal Of The American Medical Association
''JAMA'' (''The Journal of the American Medical Association'') is a peer-reviewed medical journal published 48 times a year by the American Medical Association. It publishes original research, reviews, and editorials covering all aspects of biomedicine. The journal was established in 1883 with Nathan Smith Davis as the founding editor. Kirsten Bibbins-Domingo of the University of California San Francisco became the journal editor-in-chief on July 1, 2022, succeeding Howard Bauchner of Boston University. According to ''Journal Citation Reports'', the journal's 2024 impact factor is 63.1, ranking it 4th out of 168 journals in the category "Medicine, General & Internal". History The journal was established in 1883 by the American Medical Association and superseded the ''Transactions of the American Medical Association''. ''Councilor's Bulletin'' was renamed the ''Bulletin of the American Medical Association'', which later was absorbed by the ''Journal of the American Medi ...
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Squamous-cell Carcinoma
Squamous-cell carcinoma (SCC), also known as epidermoid carcinoma, comprises a number of different types of cancer that begin in squamous cells. These cells form on the surface of the skin, on the lining of hollow organs in the body, and on the lining of the respiratory and digestive tracts. The squamous-cell carcinomas of different body sites can show differences in their presented symptoms, natural history, prognosis, and response to treatment. By body location Human papillomavirus infection has been associated with SCCs of the oropharynx, lung, fingers, and anogenital region. Head and neck cancer About 90% of cases of head and neck cancer (cancer of the mouth, nasal cavity, nasopharynx, throat and associated structures) are due to SCC. Skin Cutaneous squamous-cell carcinoma is the second most common skin cancer, accounting for over 1 million cases in the United States each year. Thyroid Primary squamous-cell carcinoma of the thyroid shows an aggressive biologica ...
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The Journal Of The American Medical Association
''JAMA'' (''The Journal of the American Medical Association'') is a peer-reviewed medical journal published 48 times a year by the American Medical Association. It publishes original research, reviews, and editorials covering all aspects of biomedicine. The journal was established in 1883 with Nathan Smith Davis as the founding editor. Kirsten Bibbins-Domingo of the University of California San Francisco became the journal editor-in-chief on July 1, 2022, succeeding Howard Bauchner of Boston University. According to ''Journal Citation Reports'', the journal's 2024 impact factor is 63.1, ranking it 4th out of 168 journals in the category "Medicine, General & Internal". History The journal was established in 1883 by the American Medical Association and superseded the ''Transactions of the American Medical Association''. ''Councilor's Bulletin'' was renamed the ''Bulletin of the American Medical Association'', which later was absorbed by the ''Journal of the American Medical ...
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American Journal Of Clinical Pathology
The ''American Journal of Clinical Pathology'' is a monthly peer-reviewed medical journal covering clinical pathology. It was established in 1931 and is published by Oxford University Press. It is the official journal of the American Society for Clinical Pathology and the Academy of Clinical Laboratory Physicians and Scientists. The editor-in-chief is Steven H. Kroft ( Medical College of Wisconsin). According to the ''Journal Citation Reports'', the journal has a 2020 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a type of journal ranking. Journals with higher impact factor values are considered more prestigious or important within their field. The Impact Factor of a journa ... of 2.493. References External links * Clinical pathology Pathology journals Oxford University Press academic journals Academic journals established in 1931 Monthly journals Academic journals associated with learned and professional societies ...
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Stroke
Stroke is a medical condition in which poor cerebral circulation, blood flow to a part of the brain causes cell death. There are two main types of stroke: brain ischemia, ischemic, due to lack of blood flow, and intracranial hemorrhage, hemorrhagic, due to bleeding. Both cause parts of the brain to stop functioning properly. Signs and symptoms of stroke may include an hemiplegia, inability to move or feel on one side of the body, receptive aphasia, problems understanding or expressive aphasia, speaking, dizziness, or homonymous hemianopsia, loss of vision to one side. Signs and symptoms often appear soon after the stroke has occurred. If symptoms last less than 24 hours, the stroke is a transient ischemic attack (TIA), also called a mini-stroke. subarachnoid hemorrhage, Hemorrhagic stroke may also be associated with a thunderclap headache, severe headache. The symptoms of stroke can be permanent. Long-term complications may include pneumonia and Urinary incontinence, loss of b ...
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Temple, Texas
Temple is a city in Bell County, Texas, United States. As of 2020, the city has a population of 82,073 according to the 2020 United States census, U.S. census. Temple lies in the region referred to as Central Texas and is a principal city in the Killeen–Temple–Fort Hood metropolitan area, (Fort Hood was redesignated "Fort Cavazos" in 2023) which as of the 2020 Census had a population of 475,367. Located off Interstate 35, Temple is 65 miles north of Austin, Texas, Austin, 34 miles south of Waco, Texas, Waco and 27 miles east of Killeen. History Temple was founded as a railroad town by the Gulf, Colorado and Santa Fe Railroad (GC&SF). The settlement began in 1880 as a GC&SF construction camp called Temple Junction. In January 1881, a post office was established, and the settlement was officially named Temple, after Bernard Moore Temple, the chief civil engineer of the GC&SF. The town was incorporated in 1882. Also in 1882, the Missouri, Kansas and Texas Railway built throug ...
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Pill Hill Historic District
The Pill Hill Historic District is a historic district roughly bounded by Boylston Street, Pond Ave., and Acron, Oakland and Highland Roads in Brookline, Massachusetts. History The district, which is mainly residential, was developed in the mid-19th century for an upper-middle class professional population. Commuter railroads connecting Brookline to Boston opened in 1848, making the town attractive for working professionals who wished to live in a more open suburban area. Several major Boston architects designed homes in the district, including Robert Swain Peabody, Walter H. Kilham, Ware & Van Brunt, and William Ralph Emerson. By the 1880s, a significant number of doctors had settled in the district, giving it its current name. Dr. Walter Channing, one of the doctors living in the district, established one of Boston's earliest women's hospitals; his efforts inspired Brookline's Free Hospital for Women, which moved to Pill Hill in 1895. The district was added to the Nati ...
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Mayo Clinic
Mayo Clinic () is a Nonprofit organization, private American Academic health science centre, academic Medical centers in the United States, medical center focused on integrated health care, healthcare, Mayo Clinic College of Medicine and Science, education, and research. It maintains three major campuses in Rochester, Minnesota; Jacksonville, Florida; and Phoenix, Arizona, Phoenix/Scottsdale, Arizona. Mayo Clinic employs over 7,300 physicians and scientists, along with another 66,000 administrative and allied health staff. The practice specializes in treating difficult cases through Health care#Tertiary care, tertiary care and Medical tourism#United States, destination medicine. It is home to the top-15 ranked Mayo Clinic Alix School of Medicine in addition to many of the highest regarded residency education programs in the United States. It spends over $660 million a year on research and has more than 3,000 full-time research personnel. William Worrall Mayo settled his family i ...
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