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Actifed
Actifed is a registered trademark for a combination antihistamine and nasal decongestant medication used for cold and allergy symptoms. Actifed was developed in 1958 by Burroughs Wellcome & Company (now part of GlaxoSmithKline), later Haleon. 2006 U.S. formula change The original formula for Actifed contained pseudoephedrine hydrochloride 60 mg as the nasal decongestant and triprolidine hydrochloride 2.5 mg as the antihistamine. However, in response to widespread laws requiring products containing pseudoephedrine to be kept behind the pharmacy counter, Pfizer changed Actifed's U.S. formula in late 2006 to contain phenylephrine HCl 10 mg as the nasal decongestant and chlorpheniramine maleate 4 mg as the antihistamine before the product was reacquired by GSK. Many users of the old formula have complained that the new formula is not as effective at relieving their symptoms. In 2023, a Food and Drug Administration panel concluded that phenylephrine was ineffecti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haleon Brands
Haleon plc is a British multinational consumer healthcare company with headquarters in Weybridge, England. It is one of the largest consumer healthcare businesses in the world, with brands including Sensodyne toothpaste, Panadol and Advil painkillers, and Centrum vitamins. The company was projected to be a global leader in over the counter medicines with a 7.3 percent market share in 2022. Haleon was established on 18 July 2022 as a corporate spin-off from GSK. Sir Dave Lewis is chairman, with Brian McNamara as CEO. Haleon is listed on the London Stock Exchange and is a component of the FTSE 100, with a secondary listing on the New York Stock Exchange. Annual sales amounted to around £10 billion across 120 markets in 2020. History GSK and Pfizer merged their consumer healthcare businesses in 2019. GSK owned just over two thirds of the joint venture, and Pfizer held the remainder. GSK announced plans to spin off Haleon in 2022, in order to give the "tired drugmaker extra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Apollo 7
Apollo 7 (October 11–22, 1968) was the first crewed flight in NASA's Apollo program, and saw the resumption of human spaceflight by the agency after the fire that had killed the three Apollo 1 astronauts during a launch rehearsal test on January 27, 1967. The Apollo7 crew commander (Apollo program), was commanded by Wally Schirra, Walter M. Schirra, with Command Module Pilot Donn F. Eisele and Lunar Module pilot Walter Cunningham, R. Walter Cunningham (so designated even though Apollo7 did not carry a Apollo Lunar Module, Lunar Module). The three astronauts were originally designated for the second crewed Apollo flight, and then as backups for Apollo1. After the Apollo1 fire, crewed flights were suspended while the cause of the accident was investigated and improvements made to the spacecraft and safety procedures, and uncrewed test flights made. Determined to prevent a repetition of the fire, the crew spent long periods monitoring the construction of their Apollo comma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haleon
Haleon plc is a British multinational consumer healthcare company with headquarters in Weybridge, England. It is one of the largest consumer healthcare businesses in the world, with brands including Sensodyne toothpaste, Panadol and Advil painkillers, and Centrum vitamins. The company was projected to be a global leader in over the counter medicines with a 7.3 percent market share in 2022. Haleon was established on 18 July 2022 as a corporate spin-off from GSK. Sir Dave Lewis is chairman, with Brian McNamara as CEO. Haleon is listed on the London Stock Exchange and is a component of the FTSE 100, with a secondary listing on the New York Stock Exchange. Annual sales amounted to around £10 billion across 120 markets in 2020. History GSK and Pfizer merged their consumer healthcare businesses in 2019. GSK owned just over two thirds of the joint venture, and Pfizer held the remainder. GSK announced plans to spin off Haleon in 2022, in order to give the "tired drugmaker ext ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pseudoephedrine
Pseudoephedrine, sold under the brand name Sudafed among others, is a sympathomimetic medication which is used as a decongestant to treat nasal congestion. It has also been used off-label for certain other indications, like treatment of low blood pressure. At higher doses, it may produce various additional effects including stimulant, appetite suppressant, and performance-enhancing effects. In relation to this, non-medical use of pseudoephedrine has been encountered. The medication is taken by mouth. Side effects of pseudoephedrine include insomnia, elevated heart rate, increased blood pressure, restlessness, dizziness, anxiety, and dry mouth, among others. Rarely, pseudoephedrine has been associated with serious cardiovascular complications like heart attack and hemorrhagic stroke. Some people may be more sensitive to its cardiovascular effects. Pseudoephedrine acts as a norepinephrine releasing agent, thereby indirectly activating adrenergic receptors. As such, it ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Triprolidine
Triprolidine is an over-the-counter antihistamine with anticholinergic properties. It is used to combat the symptoms associated with allergies and is sometimes combined with other cold medications designed to provide general relief for flu-like symptoms. As with many antihistamines, the most common side effect is drowsiness. Today, triprolidine is used less frequently and has been replaced in popular medications by other antihistamines like diphenhydramine, promethazine, chlorpheniramine, as well as second-generation antihistamines like loratadine and fexofenadine. Triprolidine remains an ingredient in the cold medicine Actifed in many territories. It was patented in 1948 and came into medical use in 1953. See also *Benzatropine *Pseudoephedrine Pseudoephedrine, sold under the brand name Sudafed among others, is a sympathomimetic medication which is used as a decongestant to treat nasal congestion. It has also been used off-label for certain other indications, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pseudoephedrine Hydrochloride
Pseudoephedrine, sold under the brand name Sudafed among others, is a sympathomimetic medication which is used as a decongestant to treat nasal congestion. It has also been used off-label for certain other indications, like treatment of low blood pressure. At higher doses, it may produce various additional effects including stimulant, appetite suppressant, and performance-enhancing effects. In relation to this, non-medical use of pseudoephedrine has been encountered. The medication is taken by mouth. Side effects of pseudoephedrine include insomnia, elevated heart rate, increased blood pressure, restlessness, dizziness, anxiety, and dry mouth, among others. Rarely, pseudoephedrine has been associated with serious cardiovascular complications like heart attack and hemorrhagic stroke. Some people may be more sensitive to its cardiovascular effects. Pseudoephedrine acts as a norepinephrine releasing agent, thereby indirectly activating adrenergic receptors. As such, it is an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Triprolidine Hydrochloride
Triprolidine is an over-the-counter antihistamine with anticholinergic properties. It is used to combat the symptoms associated with allergies and is sometimes combined with other cold medications designed to provide general relief for flu-like symptoms. As with many antihistamines, the most common side effect is drowsiness. Today, triprolidine is used less frequently and has been replaced in popular medications by other antihistamines like diphenhydramine, promethazine, chlorpheniramine, as well as second-generation antihistamines like loratadine and fexofenadine. Triprolidine remains an ingredient in the cold medicine Actifed in many territories. It was patented in 1948 and came into medical use in 1953. See also *Benzatropine *Pseudoephedrine Pseudoephedrine, sold under the brand name Sudafed among others, is a sympathomimetic medication which is used as a decongestant to treat nasal congestion. It has also been used off-label for certain other indications, li ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Registered Trademark
A trademark (also written trade mark or trade-mark) is a form of intellectual property that consists of a word, phrase, symbol, design, or a combination that identifies a product or service from a particular source and distinguishes it from others. Trademarks can also extend to non-traditional marks like drawings, symbols, 3D shapes like product designs or packaging, sounds, scents, or specific colours used to create a unique identity. For example, Pepsi® is a registered trademark associated with soft drinks, and the distinctive shape of the Coca-Cola® bottle is a registered trademark protecting Coca-Cola's packaging design. The primary function of a trademark is to identify the source of goods or services and prevent consumers from confusing them with those from other sources. Legal protection for trademarks is typically secured through registration with governmental agencies, such as the United States Patent and Trademark Office (USPTO) or the European Union Intellectual P ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Over-the-counter Drug
Over-the-counter (OTC) drugs are medicines sold directly to a consumer without a requirement for a prescription from a healthcare professional, as opposed to prescription drugs, which may be supplied only to consumers possessing a valid prescription. In many countries, OTC drugs are selected by a regulatory agency to ensure that they contain ingredients that are safe and effective when used without a physician's care. OTC drugs are usually regulated according to their active pharmaceutical ingredient (API) and strengths of final products. The term ''over-the-counter'' (''OTC'') refers to a medication that can be purchased without a medical prescription. In contrast, prescription drugs require a prescription from a doctor or other health care professional and should only be used by the prescribed individual. Some drugs may be legally classified as over-the-counter (i.e. no prescription is required), but may only be dispensed by a pharmacist after an assessment of the patient ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Apollo 12
Apollo 12 (November 14–24, 1969) was the sixth crewed flight in the United States Apollo program and the second to land on the Moon. It was launched on November 14, 1969, by NASA from the Kennedy Space Center in Florida. Commander Charles "Pete" Conrad and Lunar Module Pilot Alan L. Bean completed just over one day and seven hours of lunar surface activity while Command Module Pilot Richard F. Gordon remained in lunar orbit. Apollo 12 would have attempted the first lunar landing had Apollo 11 failed, but after the success of the earlier mission, Apollo 12 was postponed by two months, and other Apollo missions also put on a more relaxed schedule. More time was allotted for geologic training in preparation for Apollo 12 than for Apollo 11, Conrad and Bean making several geology field trips in preparation for their mission. Apollo 12's spacecraft and launch vehicle were almost identical to Apollo 11's. One addition was a set of hammocks, designed to provide Conrad and Bean ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Apollo Mission
The Apollo program, also known as Project Apollo, was the United States human spaceflight program led by NASA, which Moon landing, landed the first humans on the Moon in 1969. Apollo followed Project Mercury that put the first Americans in space. It was conceived in 1960 as a three-person spacecraft during President Presidency of Dwight D. Eisenhower, Dwight D. Eisenhower's administration. Apollo was later dedicated to President John F. Kennedy's national goal for the 1960s of "landing a man on the Moon and returning him safely to the Earth" in an address to United States Congress, Congress on May 25, 1961. It was the third American human spaceflight program to fly, preceded by Project Gemini conceived in 1961 to extend spaceflight capability in support of Apollo. Kennedy's goal was accomplished on the Apollo 11 mission when astronauts Neil Armstrong and Buzz Aldrin landed their Apollo Lunar Module (LM) on July 20, 1969, and walked on the lunar surface, while Michael Collins ( ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States
The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic of 50 U.S. state, states and a federal capital district, Washington, D.C. The 48 contiguous states border Canada to the north and Mexico to the south, with the semi-exclave of Alaska in the northwest and the archipelago of Hawaii in the Pacific Ocean. The United States asserts sovereignty over five Territories of the United States, major island territories and United States Minor Outlying Islands, various uninhabited islands in Oceania and the Caribbean. It is a megadiverse country, with the world's List of countries and dependencies by area, third-largest land area and List of countries and dependencies by population, third-largest population, exceeding 340 million. Its three Metropolitan statistical areas by population, largest metropolitan areas are New York metropolitan area, New York, Greater Los Angeles, Los Angel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
