Topic summary
Favorskii rearrangement
In organic chemistry, the Favorskii rearrangement is a reaction of α-halo ketones with a nucleophilic base to acyl derivatives. In the rearrangement, the substrate extrudes the carbonyl carbon to a primary position, which then acylates the base. In the case of cyclic α-halo ketones, the Favorskii rearrangement constitutes a ring contraction: