Zinc transporter ZIP4 is a
transmembrane protein
A transmembrane protein is a type of integral membrane protein that spans the entirety of the cell membrane. Many transmembrane proteins function as gateways to permit the transport of specific substances across the membrane. They frequently un ...
which in humans is encoded by the ''SLC39A4''
gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protei ...
. It is associated with
acrodermatitis enteropathica
Acrodermatitis enteropathica is an autosome, autosomal dominance (genetics), recessive metabolic disorder affecting the uptake of Zinc in biology, zinc through the inner lining of the bowel, the mucous membrane. It is characterized by inflammation ...
.
See also
*
Solute carrier family
The solute carrier (SLC) group of membrane transport proteins include over 400 members organized into 66 families. Most members of the SLC group are located in the cell membrane. The SLC gene nomenclature system was originally proposed by the HUGO ...
References
External links
OMIM entry on ACRODERMATITIS ENTEROPATHICA, ZINC-DEFICIENCY TYPE; AEZ
*
Solute carrier family
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