Zhong Nanshan
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Zhong Nanshan (born 20 October 1936) is a Chinese
pulmonologist Pulmonology (, , from Latin ''pulmō, -ōnis'' "lung" and the Greek Greek may refer to: Anything of, from, or related to Greece, a country in Southern Europe: *Greeks, an ethnic group *Greek language, a branch of the Indo-European language fam ...
. He was president of the
Chinese Medical Association In China, the practice of medicine is a mixture of government, charitable, and private institutions, while many people rely on traditional medicine. Until reforms in the late twentieth and early twenty-first century, physicians were quasi-governm ...
from 2005 to 2009 and is currently the editor-in-chief of the '' Journal of Thoracic Disease''. Zhong was bestowed the Medal of the Republic, the highest honorary medal of the People's Republic of China, in August 2020. Zhong earned international fame for managing the
SARS Severe acute respiratory syndrome (SARS) is a viral respiratory disease of zoonotic origin caused by the virus SARS-CoV-1, the first identified strain of the SARS-related coronavirus. The first known cases occurred in November 2002, and the ...
outbreak and was renowned for refuting the official line which downplayed the severity of the crisis. He was voted one of China's top 10 scientists in 2010. During the
COVID-19 pandemic The COVID-19 pandemic (also known as the coronavirus pandemic and COVID pandemic), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), began with an disease outbreak, outbreak of COVID-19 in Wuhan, China, in December ...
which was first identified in
Wuhan Wuhan; is the capital of Hubei, China. With a population of over eleven million, it is the most populous city in Hubei and the List of cities in China by population, eighth-most-populous city in China. It is also one of the nine National cent ...
,
Hubei Hubei is a province of China, province in Central China. It has the List of Chinese provincial-level divisions by GDP, seventh-largest economy among Chinese provinces, the second-largest within Central China, and the third-largest among inland ...
, Zhong was a leading advisor in managing the crisis, suggesting evidence-based control measures to contain the disease and sharing the successful treatment plan with the international community. He was named by ''Time'' as one of the 100 most influential people in the world in 2020.


Early life and education

Zhong was born on 20 October 1936 at the Central Hospital in
Nanjing Nanjing or Nanking is the capital of Jiangsu, a province in East China. The city, which is located in the southwestern corner of the province, has 11 districts, an administrative area of , and a population of 9,423,400. Situated in the Yang ...
,Because the hospital is located south of Zhongshan in Nanjing, his parents named it "Nanshan" according to the location of his birthplace., though his family was from
Fujian Fujian is a provinces of China, province in East China, southeastern China. Fujian is bordered by Zhejiang to the north, Jiangxi to the west, Guangdong to the south, and the Taiwan Strait to the east. Its capital is Fuzhou and its largest prefe ...
province. He was educated at
Beijing Medical University Peking University Health Science Center is the medical school of Peking University, which has 14 affiliated hospitals in Beijing, China. It was formerly the independent Beijing Medical University between 1952 and 2000. History It was first esta ...
, where he finished his residency training in internal medicine. After graduating from university in 1960, Zhong Nanshan had few opportunities to participate in clinical medicine. He once taught medicine, worked as a worker, and edited the school newspaper until he was transferred back to the Affiliated Hospital of Guangzhou Medical College in 1971. Zhong completed further training at
St Bartholomew's Hospital St Bartholomew's Hospital, commonly known as Barts, is a teaching hospital located in the City of London. It was founded in 1123 by Rahere, and is currently run by Barts Health NHS Trust. History Early history Barts was founded in 1123 by ...
in London and the
University of Edinburgh Medical School The University of Edinburgh Medical School (also known as Edinburgh Medical School) is the medical school of the University of Edinburgh in Scotland and the United Kingdom and part of the University of Edinburgh College of Medicine and Veterinar ...
between 1979 and 1981, graduating from the
University of Edinburgh Medical School The University of Edinburgh Medical School (also known as Edinburgh Medical School) is the medical school of the University of Edinburgh in Scotland and the United Kingdom and part of the University of Edinburgh College of Medicine and Veterinar ...
with an MD in 1981.


Career

Zhong Nanshan was awarded the title of one of the first batch of national-level experts with outstanding contributions in 1984. Served as graduate tutor in 1985.In 1995, he became a doctoral supervisor. In May 1996, he was elected as an academician of the Chinese Academy of Engineering. Zhong became president of the Chinese Thoracic Society in 2000 and became president of the
Chinese Medical Association In China, the practice of medicine is a mixture of government, charitable, and private institutions, while many people rely on traditional medicine. Until reforms in the late twentieth and early twenty-first century, physicians were quasi-governm ...
in 2005. He is currently the director of the Guangzhou Institute of Respiratory Diseases and editor-in-chief of the ''Journal of Thoracic Disease''. Zhong discovered the relationship between protein malnutrition and
COPD Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by chronic respiratory symptoms and airflow limitation. GOLD defines COPD as a heterogeneous lung condition characterized by chronic respiratory s ...
and has developed a calibrated formula on energy consumption for patients with COPD.


SARS outbreak

When Zhong directed the Guangzhou Institute of Respiratory Diseases, they received the second case of a
SARS Severe acute respiratory syndrome (SARS) is a viral respiratory disease of zoonotic origin caused by the virus SARS-CoV-1, the first identified strain of the SARS-related coronavirus. The first known cases occurred in November 2002, and the ...
patient as early as 20 December 2002. Over the next month, 28 similar cases were reported in
Zhongshan Zhongshan ( zh, c=中山 ), alternately romanized via Cantonese as Chungshan, is a prefecture-level city in the south of the Pearl River Delta in Guangdong province, China. As of the 2020 census, the whole city with 4,418,060 inhabitants is n ...
alone, and on 21 January 2003, Zhong and other doctors and researchers in related fields reported this disease at an emergency meeting and gave it the name
atypical pneumonia Atypical pneumonia, also known as walking pneumonia, is any type of pneumonia not caused by one of the pathogens most commonly associated with the disease. Its clinical presentation contrasts to that of "typical" pneumonia. A variety of microorga ...
. On 28 January 2003, Zhong felt sick and discovered that he had caught
pneumonia Pneumonia is an Inflammation, inflammatory condition of the lung primarily affecting the small air sacs known as Pulmonary alveolus, alveoli. Symptoms typically include some combination of Cough#Classification, productive or dry cough, ches ...
. Concerned that the news that a leading researcher and doctor for respiratory diseases falling ill during the SARS outbreak would cause fear and panic for the general public, Zhong decided to not receive treatment in the hospital. Instead he returned home, hoping that it was not caused by SARS and that he could recover without treatment. With care from his wife, Li Shaofen, he managed to recover after eight days. After recovery he immediately returned to the Guangzhou Institute of Respiratory Diseases to direct the fight against SARS. On 11 February 2003, at a press conference held by the Guangdong Department of Health, Zhong explained the disease and its symptoms, and calmed the public by asserting that it was "preventable" and "curable". Zhong, for the first time while treating SARS patients, employed
non-invasive ventilation Non-invasive ventilation (NIV) is the use of breathing support administered through a face mask, nasal mask, or a helmet. Air, usually with added oxygen, is given through the mask under positive pressure; generally the amount of pressure is alte ...
methods that increased the amount of oxygen that the patients could take in and alleviated pain. Zhong also insisted on proposing the use of
cortisone Cortisone is a pregnene (21-carbon) steroid hormone. It is a naturally-occurring corticosteroid metabolite that is also used as a pharmaceutical prodrug. Cortisol is converted by the action of the enzyme corticosteroid 11-beta-dehydrogenase ...
for the treating of patients experiencing severe conditions, which significantly lowered the death rate of severe patients to 13% and decreased the total treatment time. The decision to use cortisone was politically controversial at the time. In February 2003 the
Chinese Center for Disease Control and Prevention The Chinese Center for Disease Control and Prevention (CCDC; ) is an institution directly under the National Health Commission, based in Changping District, Beijing, China. Established in 1983, it works to protect public health and safety ...
had already published the authoritative view that normal ''
Chlamydia Chlamydia, or more specifically a chlamydia infection, is a sexually transmitted infection caused by the bacterium ''Chlamydia trachomatis''. Most people who are infected have no symptoms. When symptoms do appear, they may occur only several w ...
'' was the direct cause of atypical pneumonia and, as a result, the only legally prescribed way of treating SARS patients was to use
antibiotic An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting pathogenic bacteria, bacterial infections, and antibiotic medications are widely used in the therapy ...
s. Based on observations of hundreds of patients in
Guangdong ) means "wide" or "vast", and has been associated with the region since the creation of Guang Prefecture in AD 226. The name "''Guang''" ultimately came from Guangxin ( zh, labels=no, first=t, t= , s=广信), an outpost established in Han dynasty ...
, Zhong was determined to advocate for the moderate usage of cortisone. Zhong said later in an interview that he knew this might bring dishonor and defamation, but he persisted because he trusted in his observations and scientific judgements regarding the disease. With the support of the Guangdong government and the positive results in Guangdong in the treating of SARS disease, Zhong's method was later used as the standard protocol for treating all
SARS Severe acute respiratory syndrome (SARS) is a viral respiratory disease of zoonotic origin caused by the virus SARS-CoV-1, the first identified strain of the SARS-related coronavirus. The first known cases occurred in November 2002, and the ...
patients in China. When delegates led by Dr. Evans from the
World Health Organization The World Health Organization (WHO) is a list of specialized agencies of the United Nations, specialized agency of the United Nations which coordinates responses to international public health issues and emergencies. It is headquartered in Gen ...
visited China in early April, Zhong presented the characteristics of SARS as well as the treatment and prevention method in China. Zhong's presentation was well-received and his methods were adopted around the world.


COVID-19

In early January 2020, Zhong visited
Wuhan Wuhan; is the capital of Hubei, China. With a population of over eleven million, it is the most populous city in Hubei and the List of cities in China by population, eighth-most-populous city in China. It is also one of the nine National cent ...
, in response to a growing cluster of then-unidentified pneumonia cases, and was reassured by city health officials that the disease was controllable and preventable. On 20 January, however, he returned to Wuhan, to re-evaluate the situation, and came to the conclusion that the novel coronavirus was more transmissible than previously identified, and warned the
Central Committee of the Chinese Communist Party The Central Committee of the Chinese Communist Party, officially the Central Committee of the Communist Party of China, is the Central committee, highest organ when the National Congress of the Chinese Communist Party, national congress is not ...
that authorities in Wuhan were likely understating the severity of the outbreak, and on the same day, publicly announced on state television the same. In later reporting of his state TV broadcast he recommended that "a quarantine period of 10 days to two weeks is very effective, so there will not be a large-scale infection as people travel back from their holidays" but also concluded with the prediction that "the virus outbreak may recede in a week to 10 days." Zhong has compiled a coronavirus diagnosis and treatment protocol, and has made great contributions to the prevention and control of epidemics, treatment of severe cases, and COVID-19 research. In August 2020, he received from Chinese leader
Xi Jinping Xi Jinping, pronounced (born 15 June 1953) is a Chinese politician who has been the general secretary of the Chinese Communist Party (CCP) and Chairman of the Central Military Commission (China), chairman of the Central Military Commission ...
the Medal of the Republic, the highest state honor, for his outstanding contribution to fighting the COVID-19 epidemic. During the pandemic, Zhong had promoted publicly the usage of a controversial traditional Chinese medicine of Lianhua Qingwen capsule for treating COVID-19 infection. Though later he had denied any commercial tie with the pharmaceutical company that supplies the capsule, on 4 May 2021, an article from
Retraction Watch Retraction Watch is a blog that reports on retractions of scientific papers and on related topics. The blog was launched in August 2010 and is produced by science writers Ivan Oransky (Former Vice President, Editorial ''Medscape'') and Adam Ma ...
showed that Zhong and his coworkers were financially tied to the Yiling Pharmaceutical company that supplies the capsule. In 2020, Zhong worked with
Tencent Tencent Holdings Ltd. ( zh, s=腾讯, p=Téngxùn) is a Chinese Multinational corporation, multinational technology Conglomerate (company), conglomerate and holding company headquartered in Shenzhen. It is one of the highest grossing multimed ...
to establish an AI Joint Lab to conduct research on disease screening, prevention, and outbreak warnings. Zhong also worked on pandemic research projects with
Foxconn Hon Hai Precision Industry Co., Ltd. (), Trade name, doing business as Hon Hai Technology Group () in Taiwan, Foxconn Technology Group () in China, and Foxconn () internationally, is a Taiwanese multinational corporation, multinational electron ...
and
Alibaba Cloud Alibaba Cloud, also known as Aliyun ( zh, p=Ālǐyún, s=阿里云, l=Ali Cloud), is a cloud computing company, a subsidiary of Alibaba Group. Alibaba Cloud provides cloud computing services to online businesses and Alibaba's own e-commerce ecos ...
.


Honors

; Awards and Prizes :* 2021:
Asian Scientist 100 The Asian Scientist 100 is an annually published list of 100 prize-winning Asian researchers, academicians, innovators and business leaders from across the Asia-Pacific region and a range of scientific disciplines. Recipients "must have received ...
, ''
Asian Scientist ''Asian Scientist'' is an English language science and technology magazine published in Singapore. History and profile ''Asian Scientist'' was launched as a blog in March 2011 by Juliana Chan. The blog's popularity eventually led to a partnersh ...
'' :* 2020: Grand Lotus Medal of Honour (GML) :* 2020: Order of the Republic :* 2016: Guanghua Engineering Science and Technology Prize :* 2007: WAO Awards for Distinguished Recognition :* 2005: National Role Model of Labors :* 1997: National Award for Advances in Science and Technology, ChinaCurriculum Vitae of Nan-Shan ZHONG (PDF). 澳門科技大學. 2013 020-02-09 On 12 December 2020, the Affiliated High School of South China Normal University unveiled a bronze statue of Zhong Nanshan was unveiled on its 132nd anniversary. ; Paper of the Year :*''The Lancet''; 2008: The editorial board praised Zhong and his team, as they "clarified that
carbocisteine Carbocisteine, also called carbocysteine, is a mucolytic that reduces the viscosity of sputum and so can be used to help relieve the symptoms of chronic obstructive pulmonary disorder (COPD) and bronchiectasis by allowing the sufferer to bring u ...
can prevent the worsening of chronic obstructive pulmonary disease and can improve life at an affordable price, which is of great significance to developing countries." (Note: The editorial board selected six papers for readers to vote, and announced two winners, one selected by the editorial board and one with the highest reader votes. Zhong's paper obtained the highest number of votes.) ; Professional Titles :* 1989: Fellow of the American College of Chest Physicians :* 1993: Member of the European Respiratory Society :* 2005: Fellow of the Royal College of Physicians of Ireland :* 2011: Fellow of the Royal College of Physicians of Edinburgh :* 201?: Fellow of the Royal College of Physicians of London ; Honorary Degrees :* 2005: Honorary Fellow of Hong Kong Academy of Medicine :* 2008: Honorary Fellow of the European Respiratory Society :* 2011: Honorary Doctor of Science, University of Birmingham :* 2013: Honorary Doctor of Science, The Chinese University of Hong Kong ; Professional Societies :* 1985–1990: Member, WHO Advisory Panel on Smoking & Health :* 1982–1985: Member, Executive Committee, Chinese Medical Association :* 1989–2000: Member, Executive Committee, American College of Chest Physicians :* 1989–present: Fellow, American College of Chest Physicians (FCCP)


Personal life

Zhong was an outstanding college athlete in the 1950s. The Beijing Municipal Track and Field Team attempted to recruit him as a full-time athlete, but he was determined to become a doctor and declined the offer. Through his sports connection, he was introduced to , a basketball player who was a member of the China women's national basketball team for 13 years. And won the 1964 French "Four Nations" women's basketball championship. But because Li Shaofen was a member of the national women's basketball team at the time and could not get married, Zhong Nanshan waited for her for eight years. They married on 31 December 1963. They have two children: son Zhong Weide, a physician, who is a doctor in the Urology Department of Guangzhou First People's Hospital and the absolute main force of the hospital's basketball team, and daughter Zhong Weiyue, a swimmer, once won the short course world championship. His father, Zhong Shifan, is a doctor of medicine from the State University of New York and a pediatric medical expert. His mother, Liao Yueqin, graduated from Peking Union Medical College and is the founder of Guangdong Cancer Hospital.


See also

*
Carlo Urbani Carlo Urbani (; 19 October 1956 – 29 March 2003) was an Italian physician and microbiologist and the first to identify severe acute respiratory syndrome (SARS) as probably a new and dangerously contagious viral disease, and his early warn ...
, doctor who was the first to identify SARS and died of the disease in 2003 * Chen Wei, medical researcher who won multiple national awards * Li Lanjuan, medical researcher who won multiple national awards


References


External links

* {{DEFAULTSORT:Zhong, Nanshan 1936 births Living people Alumni of the University of Edinburgh Medical School Biologists from Jiangsu Chinese epidemiologists Chinese pulmonologists Medical journal editors Members of the Chinese Academy of Engineering Peking University alumni Physicians from Jiangsu Scientists from Nanjing 2002–2004 SARS outbreak Coronavirus researchers Chinese Communist Party politicians from Jiangsu Members of the 8th Chinese People's Political Consultative Conference Members of the 9th Chinese People's Political Consultative Conference Members of the 10th Chinese People's Political Consultative Conference Delegates to the 11th National People's Congress Delegates to the 12th National People's Congress People of Hokkien descent Recipients of the Order of the Republic (China)