Zakai is a surname. Notable people with the surname include:
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Johanan ben Zakai
:''See Yohanan for more rabbis by this name''.
Yohanan ben Zakkai ( he, יוֹחָנָן בֶּן זַכַּאי, ''Yōḥānān ben Zakkaʾy''; 1st century CE), sometimes abbreviated as Ribaz () for Rabbi Yohanan ben Zakkai, was one of the Tan ...
, Mishnah rabbi
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Moshe Zakai (born 1926), Israeli scientist
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Shafrira Zakai (born 1932), Israeli translator
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Shmuel Zakai (born 1963), Israeli general
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Yehezkel Zakai (born 1932), Israeli politician
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