ZC-B (3-(4-bromo-2,5-dimethoxyphenyl)azetidine) is a

phenethylamine Phenethylamine (PEA) is an organic compound, natural monoamine alkaloid, and trace amine, which acts as a central nervous system stimulant in humans. In the brain, phenethylamine regulates monoamine neurotransmission by binding to trace ami ...

derivative which acts as a

serotonin receptor 5-HT receptors, 5-hydroxytryptamine receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in multiple tissues including the central and peripheral nervous systems. They mediate both ex ...

agonist selective for the 5-HT₂ subtypes, with an EC₅₀ of 1.6nM at 5-HT_2A, vs 5.8nM at 5-HT_2C. It is structurally related to the psychedelic phenethylamines

2C-B 2C-B, also known as 4-bromo-2,5-dimethoxyphenethylamine or by the slang name Nexus, is a synthetic psychedelic drug of the 2C family, mainly used as a recreational drug. It was first synthesized by Alexander Shulgin in 1974 for use in psychoth ...

and

DOB DOB or Dob often refers to date of birth. DOB or Dob may also refer to: Biochemistry * 2,5-dimethoxy-4-bromoamphetamine, Bromo-DMA, a psychedelic drug ** Meta-DOB, related substance ** Methyl-DOB, related substance * HLA-DOB, human gene Organiz ...

, but with the amine side chain conformationally restricted as an azetidine ring.

References

{{Phenethylamines 2,5-Dimethoxyphenethylamines Designer drugs Serotonin receptor agonists Azetidines Bromoarenes

See also

References