In
molecular biology, Z6 small nucleolar RNA is a
non-coding RNA (ncRNA)
molecule which functions in the modification of other
small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the
nucleolus of the
eukaryotic cell which is a major site of
snRNA biogenesis. It is known as a
small nucleolar RNA
In molecular biology, Small nucleolar RNAs (snoRNAs) are a class of small RNA molecules that primarily guide chemical modifications of other RNAs, mainly ribosomal RNAs, transfer RNAs and small nuclear RNAs. There are two main classes of snoRNA, t ...
(snoRNA) and also often referred to as a guide RNA.
Z6 snoRNA belongs to the
C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-
methylation
In the chemical sciences, methylation denotes the addition of a methyl group on a substrate, or the substitution of an atom (or group) by a methyl group. Methylation is a form of alkylation, with a methyl group replacing a hydrogen atom. These t ...
of substrate RNAs.
References
External links
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Small nuclear RNA
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