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''Yarrowia'' is a fungal
The cells of ''Y. lipolytica'' have over 20% fat content, placing it in the group of oleaginous yeasts. Most lipids are stored as triacylglycerids (TAGs). This physiological trait makes this species especially interesting for producing lipid derivates. For example, genetic engineering and process optimization allow it to produce high amounts of
''Yarrowia lipolytica'' has dimorphic growth, which means it can grow in two different phenotypes. The usual form of the cells can be described as round and spherical. When exposed to stressful conditions such as temperature, pH, mechanical or osmotic stress, the cell can switch into a filamentous growth form (also see
genus
Genus (; : genera ) is a taxonomic rank above species and below family (taxonomy), family as used in the biological classification of extant taxon, living and fossil organisms as well as Virus classification#ICTV classification, viruses. In bino ...
in the family Dipodascaceae
The Dipodascaceae are a family of yeasts in the order Saccharomycetales. According to the 2007 Outline of Ascomycota, the family contains four genera; however, the placement of ''Sporopachydermia'' and ''Yarrowia'' is uncertain.
GBIF accepted ...
. For a while the genus was monotypic
In biology, a monotypic taxon is a taxonomic group (taxon) that contains only one immediately subordinate taxon. A monotypic species is one that does not include subspecies or smaller, infraspecific taxa. In the case of genera, the term "unisp ...
, containing the single species ''Yarrowia lipolytica'', a yeast
Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom (biology), kingdom. The first yeast originated hundreds of millions of years ago, and at least 1,500 species are currently recognized. They are est ...
that can use unusual carbon sources, such as hydrocarbon
In organic chemistry, a hydrocarbon is an organic compound consisting entirely of hydrogen and carbon. Hydrocarbons are examples of group 14 hydrides. Hydrocarbons are generally colourless and Hydrophobe, hydrophobic; their odor is usually fain ...
s. This has made it of interest for use in industrial microbiology
Industrial microbiology is a branch of biotechnology that applies microbial sciences to create industrial products in mass quantities, often using Microbial cell factory, microbial cell factories. There are multiple ways to manipulate a microorgani ...
, especially for the production of specialty lipid
Lipids are a broad group of organic compounds which include fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, and others. The functions of lipids include storing ...
s. Molecular phylogenetics
Molecular phylogenetics () is the branch of phylogeny that analyzes genetic, hereditary molecular differences, predominantly in DNA sequences, to gain information on an organism's evolutionary relationships. From these analyses, it is possible to ...
analysis has revealed several other species that have since been added to the genus.
In January 2019, ''Yarrowia lipolytica'' yeast biomass
Biomass is a term used in several contexts: in the context of ecology it means living organisms, and in the context of bioenergy it means matter from recently living (but now dead) organisms. In the latter context, there are variations in how ...
was defined by the European Food Safety Authority
The European Food Safety Authority (EFSA) is the agency of the European Union (EU) that provides independent scientific advice and communicates on existing and emerging risks associated with the food chain. EFSA was established in February 2002 ...
as a safe novel food
A novel food is a type of food that does not have a significant history of consumption or is produced by a method that has not previously been used for food.
Designer food
Designer food is a type of novel food that has not existed on any regional ...
– dried and heat‐killed – with the underlying qualifications that it is widespread in nature, present in the typical environment, may be used as food for people over age 3 (3 grams per day for children under age 10, and 6 grams per day for teens and adults), and may be manufactured as a dietary supplement
A dietary supplement is a manufactured product intended to supplement a person's diet by taking a pill (pharmacy), pill, capsule (pharmacy), capsule, tablet (pharmacy), tablet, powder, or liquid. A supplement can provide nutrients eithe ...
.
Biology
Habitat
''Yarrowia lipolytica'' has been isolated from various locations (e.g. milled corn fiber tailings or Paris sewers). Often these environments contain an excess of lipids, which can be efficiently utilized by ''Y. lipolytica'' as a carbon and energy source. This species is strictlyaerobic
Aerobic means "requiring air," in which "air" usually means oxygen.
Aerobic may also refer to
* Aerobic exercise, prolonged exercise of moderate intensity
* Aerobics, a form of aerobic exercise
* Aerobic respiration, the aerobic process of cellu ...
.
Oleaginous yeast
The cells of ''Y. lipolytica'' have over 20% fat content, placing it in the group of oleaginous yeasts. Most lipids are stored as triacylglycerids (TAGs). This physiological trait makes this species especially interesting for producing lipid derivates. For example, genetic engineering and process optimization allow it to produce high amounts of eicosapentaenoic acid
Eicosapentaenoic acid (EPA; also icosapentaenoic acid) is an omega−3 fatty acid. In physiological literature, it is given the name 20:5(''n''−3). It also has the trivial name timnodonic acid. In chemical structure, EPA is a carboxylic acid wi ...
(EPA).
Dimorphism
''Yarrowia lipolytica'' has dimorphic growth, which means it can grow in two different phenotypes. The usual form of the cells can be described as round and spherical. When exposed to stressful conditions such as temperature, pH, mechanical or osmotic stress, the cell can switch into a filamentous growth form (also see hypha
A hypha (; ) is a long, branching, filamentous structure of a fungus, oomycete, or actinobacterium. In most fungi, hyphae are the main mode of vegetative growth, and are collectively called a mycelium.
Structure
A hypha consists of one o ...
e).
Genome
The genome of ''Y. lipolytica'' consists of around 20.5 Mbp (mega base pairs), encodes for over 7000 genes and is distributed on sixchromosome
A chromosome is a package of DNA containing part or all of the genetic material of an organism. In most chromosomes, the very long thin DNA fibers are coated with nucleosome-forming packaging proteins; in eukaryotic cells, the most import ...
s (named A to F) and the mitochondrial DNA
Mitochondrial DNA (mtDNA and mDNA) is the DNA located in the mitochondrion, mitochondria organelles in a eukaryotic cell that converts chemical energy from food into adenosine triphosphate (ATP). Mitochondrial DNA is a small portion of the D ...
(M). Naturally, there are small differences in the length of the genomes of different strain isolates. Usually hemiascomycetous yeast have a low number of intron
An intron is any nucleotide sequence within a gene that is not expressed or operative in the final RNA product. The word ''intron'' is derived from the term ''intragenic region'', i.e., a region inside a gene."The notion of the cistron .e., gen ...
s, but ''Y. lipolytica'' is an exception with about 15% of genes containing introns.
References
{{Taxonbar, from=Q10723443 Ascomycota genera Saccharomycetes Taxa described in 1981