A wide local excision (WLE) is a
surgical
Surgery is a medical specialty that uses manual and instrumental techniques to diagnose or treat pathological conditions (e.g., trauma, disease, injury, malignancy), to alter bodily functions (e.g., malabsorption created by bariatric surgery ...
procedure to remove a small area of diseased or problematic tissue with a margin of normal tissue. This procedure is commonly performed on the breast and to skin lesions, but can be used on any area of the body.
The tissue removed is examined under a microscope to confirm the type of lesion and to grade malignant
tumour
A neoplasm () is a type of abnormal and excessive growth of tissue (biology), tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tiss ...
s. This examination also determines if all of the lesion has been removed without leaving any behind.
The results of a WLE will determine any future treatments if needed.
Wide local excision of the breast
A wide local excision of the
breast
The breasts are two prominences located on the upper ventral region of the torso among humans and other primates. Both sexes develop breasts from the same embryology, embryological tissues. The relative size and development of the breasts is ...
aims to remove benign and malignant lesions while conserving the normal shape of the breast as much as possible. It is a form of
breast-conserving surgery. A WLE can only be used for lesions up to 4 cm in diameter, as removal of any larger lesions could leave a visibly dented area in the breast. The extent of excision is variable, ranging from
lumpectomy
Lumpectomy (sometimes known as a tylectomy, partial mastectomy, breast segmental resection or breast wide local excision) is a surgical removal of a discrete portion or "lump" of breast tissue, usually in the treatment of a malignant tumor or bre ...
to
quadrantectomy. A larger excision would be categorised as a
mastectomy
Mastectomy is the medical term for the surgical removal of one or both breasts, partially or completely. A mastectomy is usually carried out to treat breast cancer. In some cases, women believed to be at high risk of breast cancer choose to have ...
instead.
Wide Local Excision
Livestrong.com. Accessed April 11, 2012.
References
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Surgical removal procedures
Breast cancer
Breast surgery