''Vincetoxicum auriculatum'',

synonym A synonym is a word, morpheme, or phrase that means precisely or nearly the same as another word, morpheme, or phrase in a given language. For example, in the English language, the words ''begin'', ''start'', ''commence'', and ''initiate'' are a ...

''Cynanchum auriculatum'', is a species of climbing vine. Its Chinese name is ''niu pi xiao'' 牛皮消 (leather eater). ''V. auriculatum'' flowers between June and August; fruiting from August all the way to December.

Distribution and habitat

''Vincetoxicum auriculatum'' is native to Asian temperate and tropical regions; found in

China China, officially the People's Republic of China (PRC), is a country in East Asia. With population of China, a population exceeding 1.4 billion, it is the list of countries by population (United Nations), second-most populous country after ...

(in

Sichuan Sichuan is a province in Southwestern China, occupying the Sichuan Basin and Tibetan Plateau—between the Jinsha River to the west, the Daba Mountains to the north, and the Yunnan–Guizhou Plateau to the south. Its capital city is Cheng ...

Xizang The Tibet Autonomous Region (TAR), often shortened to Tibet in English or Xizang in Hanyu Pinyin, is an autonomous region of the People's Republic of China. It was established in 1965 to replace the Tibet Area, a former administrative divisio ...

, and

Yunnan Yunnan; is an inland Provinces of China, province in Southwestern China. The province spans approximately and has a population of 47.2 million (as of 2020). The capital of the province is Kunming. The province borders the Chinese provinces ...

provinces),

Bhutan Bhutan, officially the Kingdom of Bhutan, is a landlocked country in South Asia, in the Eastern Himalayas between China to the north and northwest and India to the south and southeast. With a population of over 727,145 and a territory of , ...

Nepal Nepal, officially the Federal Democratic Republic of Nepal, is a landlocked country in South Asia. It is mainly situated in the Himalayas, but also includes parts of the Indo-Gangetic Plain. It borders the Tibet Autonomous Region of China Ch ...

, and the northern parts of

Pakistan Pakistan, officially the Islamic Republic of Pakistan, is a country in South Asia. It is the List of countries and dependencies by population, fifth-most populous country, with a population of over 241.5 million, having the Islam by country# ...

and

India India, officially the Republic of India, is a country in South Asia. It is the List of countries and dependencies by area, seventh-largest country by area; the List of countries by population (United Nations), most populous country since ...

(it is also native to

Kashmir Kashmir ( or ) is the Northwestern Indian subcontinent, northernmost geographical region of the Indian subcontinent. Until the mid-19th century, the term ''Kashmir'' denoted only the Kashmir Valley between the Great Himalayas and the Pir P ...

). Its

habitat In ecology, habitat refers to the array of resources, biotic factors that are present in an area, such as to support the survival and reproduction of a particular species. A species' habitat can be seen as the physical manifestation of its ...

mountain A mountain is an elevated portion of the Earth's crust, generally with steep sides that show significant exposed bedrock. Although definitions vary, a mountain may differ from a plateau in having a limited summit area, and is usually higher t ...

ous

shrubland Shrubland, scrubland, scrub, brush, or bush is a plant community characterized by vegetation dominance (ecology), dominated by shrubs, often also including grasses, herbaceous plant, herbs, and geophytes. Shrubland may either occur naturally o ...

terrain, at elevations from 2800 to 3600 meters.

Studies

Ethanol Ethanol (also called ethyl alcohol, grain alcohol, drinking alcohol, or simply alcohol) is an organic compound with the chemical formula . It is an Alcohol (chemistry), alcohol, with its formula also written as , or EtOH, where Et is the ps ...

extracts derived from

root In vascular plants, the roots are the plant organ, organs of a plant that are modified to provide anchorage for the plant and take in water and nutrients into the plant body, which allows plants to grow taller and faster. They are most often bel ...

s of ''V. auriculatum'' are being studied for use in anti-cancer medicine; one preliminary study found extracts to have some

cytotoxic Cytotoxicity is the quality of being toxic to cells. Examples of toxic agents are toxic metals, toxic chemicals, microbe neurotoxins, radiation particles and even specific neurotransmitters when the system is out of balance. Also some types of dr ...

effects on certain human

tumor A neoplasm () is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists ...

cell lines. The tests were conducted, both ''

in vitro ''In vitro'' (meaning ''in glass'', or ''in the glass'') Research, studies are performed with Cell (biology), cells or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in ...

'' and ''

in vivo Studies that are ''in vivo'' (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, an ...

'', on both human subjects, and

mice A mouse (: mice) is a small rodent. Characteristically, mice are known to have a pointed snout, small rounded ears, a body-length scaly tail, and a high breeding rate. The best known mouse species is the common house mouse (''Mus musculus' ...

References

External links

A photo
of ''C. auriculatum'', from

Flora of China The flora of China consists of a diverse range of plant species including over 39,000 vascular plants, 27,000 species of fungi and 3000 species of bryophytes.Wu, Z. Y., P. H. Raven & D. Y. Hong, eds. 2006. Flora of China. Vol. 22 (Poaceae). Sci ...

, courtesy of the

Harvard University Herbaria The Harvard University Herbaria and Botanical Museum are institutions located on the grounds of Harvard University at 22 Divinity Avenue, Cambridge, Massachusetts. The Botanical Museum is one of three which comprise the Harvard Museum of Natura ...

auriculatum Flora of East Himalaya Flora of West Himalaya Flora of Nepal Flora of Pakistan Flora of South-Central China Flora of Tibet Plants described in 1834 {{Apocynaceae-stub