Vilanterol is an
ultra-long-acting β2-adrenoceptor agonist which was approved in May 2013 in combination with
fluticasone furoate for sale as
Breo Ellipta by
GlaxoSmithKline
GSK plc (an acronym from its former name GlaxoSmithKline plc) is a British Multinational corporation, multinational Pharmaceutics, pharmaceutical and biotechnology company with headquarters in London. It was established in 2000 by a Mergers an ...
for the treatment of
chronic obstructive pulmonary disease
Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by chronic respiratory symptoms and airflow limitation. GOLD defines COPD as a heterogeneous lung condition characterized by chronic respiratory s ...
(COPD).
The combination is also approved for the treatment of
asthma
Asthma is a common long-term inflammatory disease of the airways of the lungs. It is characterized by variable and recurring symptoms, reversible airflow obstruction, and easily triggered bronchospasms. Symptoms include episodes of wh ...
in Canada, Europe, Japan
and New Zealand.
Vilanterol is available in following combinations:
* with inhaled
corticosteroid
Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Two main classes of corticosteroids, glucocorticoids and mineralocorticoids, are invo ...
fluticasone furoate—
fluticasone furoate/vilanterol (trade names Breo Ellipta
(U.S.
The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic of 50 states and a federal capital district, Washington, D.C. The 48 contiguous ...
, NZ), Relvar Ellipta
( EU, RU, JPN))
* with
muscarinic antagonist
A muscarinic acetylcholine receptor antagonist, also simply known as a muscarinic antagonist or as an antimuscarinic agent, is a type of anticholinergic drug that blocks the activity of the muscarinic acetylcholine receptors (mAChRs). The muscarin ...
umeclidinium bromide—
umeclidinium bromide/vilanterol (trade name Anoro Ellipta)
* with inhaled
corticosteroid
Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Two main classes of corticosteroids, glucocorticoids and mineralocorticoids, are invo ...
fluticasone furoate and
muscarinic antagonist
A muscarinic acetylcholine receptor antagonist, also simply known as a muscarinic antagonist or as an antimuscarinic agent, is a type of anticholinergic drug that blocks the activity of the muscarinic acetylcholine receptors (mAChRs). The muscarin ...
umeclidinium bromide—
fluticasone furoate/umeclidinium bromide/vilanterol (trade name Trelegy Ellipta)
See also
*
Salmeterol
Salmeterol is a Long-acting beta-adrenoceptor agonist, long-acting β2 adrenergic receptor agonist (LABA) used in the treatment and prevention of asthma symptoms and control of chronic obstructive pulmonary disease (COPD) symptoms. Symptoms of b ...
—the long-acting β
2-adrenergic receptor agonist from which vilanterol was derived.
References
Long-acting beta2-adrenergic agonists
Phenylethanolamines
Chloroarenes
Secondary amines
{{respiratory-system-drug-stub