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ViiV Healthcare ( ) is a British multinational pharmaceutical company specializing in the research and development of medicines to treat and prevent
HIV/AIDS The HIV, human immunodeficiency virus (HIV) is a retrovirus that attacks the immune system. Without treatment, it can lead to a spectrum of conditions including acquired immunodeficiency syndrome (AIDS). It is a Preventive healthcare, pr ...
. Its global headquarters is located in
London London is the Capital city, capital and List of urban areas in the United Kingdom, largest city of both England and the United Kingdom, with a population of in . London metropolitan area, Its wider metropolitan area is the largest in Wester ...
. The company was created as a joint venture by GSK and
Pfizer Pfizer Inc. ( ) is an American Multinational corporation, multinational Pharmaceutical industry, pharmaceutical and biotechnology corporation headquartered at The Spiral (New York City), The Spiral in Manhattan, New York City. Founded in 184 ...
in November 2009, with both companies transferring their HIV assets to the new company.Jacks, Andre
"GSK and Pfizer to Merge HIV Portfolios
Financial Times. 16 April 2010
In 2012,
Shionogi is a Japanese pharmaceutical company best known for developing Crestor. Medical supply and brand name also uses katakana (シオノギ). Shionogi has business roots that date back to 1878, and was incorporated in 1919. Among the medicines pr ...
joined the company. As of December 2023, 76.5% of the company is owned by GSK, 13.5% by Pfizer and 10% by Shionogi. According to The Financial Times, the company's co-ownership structure may change depending on the achievement of certain milestones. ViiV Healthcare's products have a market share of approximately 32% of the global HIV therapy market, making it the second-largest healthcare company in the sector, after
Gilead Sciences Gilead Sciences, Inc. () is an American biopharmaceutical company headquartered in Foster City, California, that focuses on researching and developing antiviral drugs used in the treatment of HIV/AIDS, hepatitis B, hepatitis C, influenza, and CO ...
. ViiV Healthcare's global headquarters are in
London London is the Capital city, capital and List of urban areas in the United Kingdom, largest city of both England and the United Kingdom, with a population of in . London metropolitan area, Its wider metropolitan area is the largest in Wester ...
in the
United Kingdom The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Northwestern Europe, off the coast of European mainland, the continental mainland. It comprises England, Scotlan ...
, and the company has sites in a number of other countries including the United States, Australia, Belgium, Canada, France, Germany, Italy, Japan, Mexico, the Netherlands, Portugal, Puerto Rico, Russia, Spain and Switzerland.


Products

The company markets 17 products: * Nucleoside reverse transcriptase inhibitors (NRTIs): **
abacavir Abacavir, sold under the brand name Ziagen among others, is a medication used to treat HIV/AIDS. Similar to other nucleoside analog reverse-transcriptase inhibitors (NRTIs), abacavir is used together with other HIV medications, and is not re ...
(brand name Ziagen) **
lamivudine Lamivudine, commonly called 3TC, is an antiretroviral medication used to prevent and treat HIV/AIDS. It is also used to treat chronic hepatitis B when other options are not possible. It is effective against both HIV-1 and HIV-2. It is typi ...
(brand names Epivir and 3TC) **
zidovudine Zidovudine (ZDV), also known as azidothymidine (AZT), was the first antiretroviral medication used to prevent and treat HIV/AIDS. It is generally recommended for use in combination with other antiretrovirals. It may be used to prevent mothe ...
(brand name Retrovir and AZT) * Non-nucleoside reverse transcriptase inhibitors (NNRTIs): **
delavirdine Delavirdine (DLV) (brand name Rescriptor) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) marketed by ViiV Healthcare. It is used as part of highly active antiretroviral therapy (HAART) for the treatment of human immunodeficiency viru ...
(brand name Rescriptor, no longer available) * Attachment inhibitors **
fostemsavir Fostemsavir, sold under the brand name Rukobia, is an antiretroviral medication for adults living with HIV/AIDS who have tried multiple HIV medications and whose HIV infection cannot be successfully treated with other therapies because of resist ...
(brand name Rukobia) * Integrase strand transfer inhibitors (INSTIs): **
dolutegravir Dolutegravir (DTG), sold under the brand name Tivicay, is an antiretroviral medication used, together with other medication, to treat HIV/AIDS. It may also be used, as part of post exposure prophylaxis, to prevent HIV infection following poten ...
(brand name Tivicay) **
cabotegravir Cabotegravir, sold under the brand name Vocabria among others, is an antiretroviral medication used for the treatment and prevention of HIV/AIDS. It is available in the form of tablets and as an intramuscular injection, as well as in an inject ...
(brand names Apretude
PrEP PowerPC Reference Platform (PReP) was a standard system architecture for PowerPC-based computer systems (as well as a reference implementation) developed at the same time as the PowerPC processor architecture. Published by IBM in 1994, it allow ...
]; and Cabenuva, Vocabria/Cabenuva [when co-administered with rilpivirine for HIV treatment – in partnership with
Janssen Pharmaceuticals Johnson & Johnson Innovative Medicine (formerly Janssen Pharmaceuticals) is a Belgian pharmaceutical company headquartered in Beerse, Belgium, and wholly owned by Johnson & Johnson. It was founded in 1953 by Paul Janssen. In 1961, Janssen Ph ...
]) * Protease inhibitor (pharmacology), Protease inhibitors: **
fosamprenavir Fosamprenavir (FPV), sold under the brand names Lexiva and Telzir, is a medication used to treat HIV/AIDS. It is a prodrug of the protease inhibitor and antiretroviral drug amprenavir. It is marketed by ViiV Healthcare as the calcium salt. Fos ...
(brand names Lexiva and Telzir) **
nelfinavir Nelfinavir, sold under the brand name Viracept, is an antiretroviral medication used in the treatment of HIV/AIDS. Nelfinavir belongs to the class of drugs known as protease inhibitor (pharmacology), protease inhibitors (PIs) and like other PIs ...
(brand name Viracept) *
Entry inhibitor Entry inhibitors, also known as fusion inhibitors, are a class of antiviral drugs that prevent a virus from entering a cell, for example, by blocking a receptor. Entry inhibitors are used to treat conditions such as HIV and hepatitis D. HIV entry ...
s: **
maraviroc Maraviroc, sold under the brand names Selzentry (US) and Celsentri (EU), is an antiretroviral medication used to treat HIV infection. It is taken by mouth. It is in the CCR5 receptor antagonist class. It was approved for medical use in the Un ...
(brand names Selzentry and Celsentri) * Antiretroviral fixed-dose combinations, including several single-pill regimens: ** abacavir/lamivudine (brand names Epzicom and Kivexa) **
abacavir/lamivudine/zidovudine Abacavir/lamivudine/zidovudine, sold under the brand name Trizivir, is a fixed-dose combination antiretroviral medication for the treatment of HIV/AIDS. It contains three reverse transcriptase inhibitors patented by GlaxoSmithKline and markete ...
(brand name Trizivir) **
lamivudine/zidovudine Lamivudine/zidovudine, sold under the brand name Combivir among others, is a fixed-dose combination antiretroviral medication used to treat HIV/AIDS. It contains two antiretroviral medications, lamivudine and zidovudine. It is used together w ...
(brand name Combivir) **
abacavir/dolutegravir/lamivudine Abacavir/dolutegravir/lamivudine, sold under the brand name Triumeq among others, is a fixed-dose combination antiretroviral medication for the treatment of HIV/AIDS. It is a combination of three medications with different and complementary mec ...
(brand name Triumeq) ** dolutegravir/lamivudine (brand name Dovato) ** dolutegravir/rilpivirine (brand name Juluca – in partnership with
Janssen Pharmaceuticals Johnson & Johnson Innovative Medicine (formerly Janssen Pharmaceuticals) is a Belgian pharmaceutical company headquartered in Beerse, Belgium, and wholly owned by Johnson & Johnson. It was founded in 1953 by Paul Janssen. In 1961, Janssen Ph ...
)


Treatment access programs

ViiV Healthcare has stated that it will continue the not-for-profit pricing schemes that
Pfizer Pfizer Inc. ( ) is an American Multinational corporation, multinational Pharmaceutical industry, pharmaceutical and biotechnology corporation headquartered at The Spiral (New York City), The Spiral in Manhattan, New York City. Founded in 184 ...
and
GlaxoSmithKline GSK plc (an acronym from its former name GlaxoSmithKline plc) is a British Multinational corporation, multinational Pharmaceutics, pharmaceutical and biotechnology company with headquarters in London. It was established in 2000 by a Mergers an ...
had been involved in prior to the setting up of the company. This program covers all low- and middle-income countries, as well as all of
Sub-Saharan Africa Sub-Saharan Africa is the area and regions of the continent of Africa that lie south of the Sahara. These include Central Africa, East Africa, Southern Africa, and West Africa. Geopolitically, in addition to the list of sovereign states and ...
."ViiV Healthcare Company Website. We Improve Access to Our Medicines"
Accessed 12 January 2014
The company has also granted voluntary licenses to 14 generics companies to enable the low-cost manufacture and sale of generic versions of the company's products in specific countries and/or regions. In March 2020, ViiV Healthcare announced the initiation of a study in partnership with
University of South Carolina The University of South Carolina (USC, SC, or Carolina) is a Public university, public research university in Columbia, South Carolina, United States. Founded in 1801 as South Carolina College, It is the flagship of the University of South Car ...
's Ryan White Program to determine the effectiveness of ride-sharing services in improving access to care for people living with HIV.


See also

*
Pharmaceutical industry in the United Kingdom The pharmaceutical industry in the United Kingdom directly employs around 73,000 people and in 2007 contributed £8.4 billion to the UK's GDP and invested a total of £3.9 billion in research and development. In 2007 exports of pharmaceutical pr ...
*
List of pharmaceutical companies This listing is limited to those pharmaceutical companies, independent companies and subsidiaries notable enough to have their own articles in Wikipedia. Both going concerns and defunct firms are included, as well as firms that were part of the ...


References

{{Authority control Pharmaceutical companies of the United Kingdom Pharmaceutical companies established in 2009 Joint ventures GSK plc Pfizer Life sciences industry Specialty drugs