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Sir Victor Alexander Haden Horsley (14 April 1857 – 16 July 1916) was a British scientist and professor. He was born in
Kensington Kensington is an area of London in the Royal Borough of Kensington and Chelsea, around west of Central London. The district's commercial heart is Kensington High Street, running on an east–west axis. The north-east is taken up by Kensingt ...
, London. Educated at Cranbrook School, Kent, he studied medicine at
University College London University College London (Trade name, branded as UCL) is a Public university, public research university in London, England. It is a Member institutions of the University of London, member institution of the Federal university, federal Uni ...
and in Berlin, Germany (1881) and, in the same year, started his career as a house surgeon and registrar at the
University College Hospital University College Hospital (UCH) is a teaching hospital in the Fitzrovia area of the London Borough of Camden, England. The hospital, which was founded as the North London Hospital in 1834, is closely associated with University College Lo ...
. From 1884 to 1890, Horsley was Professor-Superintendent of the Brown Institute. In 1886, he was appointed as Assistant Professor of Surgery at the National Hospital for Paralysis and Epilepsy, and as a Professor of Pathology (1887–1896) and Professor of Clinical Surgery (1899–1902) at University College London. He was a supporter of
women's suffrage Women's suffrage is the women's rights, right of women to Suffrage, vote in elections. Several instances occurred in recent centuries where women were selectively given, then stripped of, the right to vote. In Sweden, conditional women's suffra ...
and was an opponent of tobacco and alcohol.


Personal life

Victor Alexander Haden Horsley was born in Kensington, London, the son of Rosamund (Haden) and
John Callcott Horsley John Callcott Horsley (29 January 1817 – 18 October 1903) was a British academic Painting, painter of genre painting, genre and historical scenes, illustrator, and designer of the first Christmas card. He was a member of the artist's colony ...
, R.A. and the brother of Rosamund Brunel Horsley. His given name, Victor Alexander, was given to him by
Queen Victoria Victoria (Alexandrina Victoria; 24 May 1819 – 22 January 1901) was Queen of the United Kingdom of Great Britain and Ireland from 20 June 1837 until Death and state funeral of Queen Victoria, her death in January 1901. Her reign of 63 year ...
. In 1883, he became engaged to Eldred Bramwell, daughter of Sir Frederick Bramwell. On 4 October 1887, Victor and Eldred married at St. Margaret's, Westminster. They had two sons, Siward and Oswald, and a daughter, Pamela. He was
knighted A knight is a person granted an honorary title of a knighthood by a head of state (including the pope) or representative for service to the monarch, the church, or the country, especially in a military capacity. The concept of a knighthood ...
in the 1902 Coronation Honours, receiving the accolade from King
Edward VII Edward VII (Albert Edward; 9 November 1841 – 6 May 1910) was King of the United Kingdom and the British Dominions, and Emperor of India, from 22 January 1901 until Death and state funeral of Edward VII, his death in 1910. The second child ...
at
Buckingham Palace Buckingham Palace () is a royal official residence, residence in London, and the administrative headquarters of the monarch of the United Kingdom. Located in the City of Westminster, the palace is often at the centre of state occasions and r ...
on 24 October that year. Horsley was a champion of many causes. One of his primary life crusades was the temperance movement. Having observed that many injuries admitted to the hospital were due to alcohol, Horsley threw himself into becoming a temperance reformer. He soon rose up to the position of vice president of the National Temperance League and the president of the British Medical Temperance Association. In 1907, along with Dr. Mary Sturge, he published a book on alcoholism titled ''Alcohol and the Human Body''. According to his biographers, Tan & Black (2002), "Horsley's kindness, humility, and generous spirit endeared him to patients, colleagues, and students. Born to privilege, he was nonetheless dedicated to improving the lot of the common man and directed his efforts toward the
suffrage Suffrage, political franchise, or simply franchise is the right to vote in public, political elections and referendums (although the term is sometimes used for any right to vote). In some languages, and occasionally in English, the right to v ...
of women, medical reform, and free health care for the working class (...) An
iconoclast Iconoclasm ()From . ''Iconoclasm'' may also be considered as a back-formation from ''iconoclast'' (Greek: εἰκοκλάστης). The corresponding Greek word for iconoclasm is εἰκονοκλασία, ''eikonoklasia''. is the social belie ...
of keen intellect, unlimited energy, and consummate skill, his life and work justifies his epitaph as a "pioneer of neurological surgery".


Medical career

Horsley specialised in surgery and in
physiology Physiology (; ) is the science, scientific study of function (biology), functions and mechanism (biology), mechanisms in a life, living system. As a branches of science, subdiscipline of biology, physiology focuses on how organisms, organ syst ...
. He was the first physician to remove a spinal tumor, in 1887, by means of a
laminectomy A laminectomy is a surgical procedure that removes a portion of a vertebra called the Lamina of the vertebral arch, lamina, which is the roof of the spinal canal. It is a major spine operation with residual scar tissue and may result in postla ...
. He developed many practical neurosurgical techniques, including the hemostatic bone wax, the skin flap, the ligation of the
carotid artery Carotid artery may refer to: * Common carotid artery, often "carotids" or "carotid", an artery on each side of the neck which divides into the external carotid artery and internal carotid artery * External carotid artery, an artery on each side of ...
to treat cerebral
aneurysm An aneurysm is an outward :wikt:bulge, bulging, likened to a bubble or balloon, caused by a localized, abnormal, weak spot on a blood vessel wall. Aneurysms may be a result of a hereditary condition or an acquired disease. Aneurysms can also b ...
s, the transcranial approach to the
pituitary gland The pituitary gland or hypophysis is an endocrine gland in vertebrates. In humans, the pituitary gland is located at the base of the human brain, brain, protruding off the bottom of the hypothalamus. The pituitary gland and the hypothalamus contr ...
and the intradural division of the
trigeminal nerve In neuroanatomy, the trigeminal nerve (literal translation, lit. ''triplet'' nerve), also known as the fifth cranial nerve, cranial nerve V, or simply CN V, is a cranial nerve responsible for Sense, sensation in the face and motor functions ...
root for the surgical treatment of
trigeminal neuralgia Trigeminal neuralgia (TN or TGN), also called Fothergill disease, tic douloureux, trifacial neuralgia, is a chronic pain, long-term pain disorder that affects the trigeminal nerve, the nerve responsible for sensation in the face and motor funct ...
. As a neuroscientist, he carried out studies of the functions of the brain in animals and humans, particularly on the
cerebral cortex The cerebral cortex, also known as the cerebral mantle, is the outer layer of neural tissue of the cerebrum of the brain in humans and other mammals. It is the largest site of Neuron, neural integration in the central nervous system, and plays ...
. His studies on motor response to faradic
electrical stimulation Functional electrical stimulation (FES) is a technique that uses low-energy electrical pulses to artificially generate body movements in individuals who have been paralyzed due to injury to the central nervous system. More specifically, FES ca ...
of the cerebral cortex,
internal capsule The internal capsule is a paired white matter structure, as a two-way nerve tract, tract, carrying afferent nerve fiber, ascending and efferent nerve fiber, descending axon, fibers, to and from the cerebral cortex. The internal capsule is situate ...
and
spinal cord The spinal cord is a long, thin, tubular structure made up of nervous tissue that extends from the medulla oblongata in the lower brainstem to the lumbar region of the vertebral column (backbone) of vertebrate animals. The center of the spinal c ...
became classics of the field. Those studies later translated into his pioneering work on
neurosurgery Neurosurgery or neurological surgery, known in common parlance as brain surgery, is the specialty (medicine), medical specialty that focuses on the surgical treatment or rehabilitation of disorders which affect any portion of the nervous system ...
for
epilepsy Epilepsy is a group of Non-communicable disease, non-communicable Neurological disorder, neurological disorders characterized by a tendency for recurrent, unprovoked Seizure, seizures. A seizure is a sudden burst of abnormal electrical activit ...
. Between 1884 and 1886, Horsley was the first to use intraoperative electrical stimulation of the cortex for the localization of epileptic foci in humans, preceding Fedor Krause and
Wilder Penfield Wilder Graves Penfield (January 26, 1891April 5, 1976) was an American-Canadian neurosurgeon. He expanded brain surgery's methods and techniques, including mapping the functions of various regions of the brain such as the cortical homunculus. ...
. He was also a pioneer in the study of the functions of the
thyroid The thyroid, or thyroid gland, is an endocrine gland in vertebrates. In humans, it is a butterfly-shaped gland located in the neck below the Adam's apple. It consists of two connected lobes. The lower two thirds of the lobes are connected by ...
gland. He studied myxedema and cretinism, which are caused by a decreased level of the thyroid hormones (hypothyroidism), and established for the first time, in experiments with monkeys, that they could be treated with extracts of the gland. Appointed in 1886 as secretary to a governmental commission formed to study the anti-rabies
vaccine A vaccine is a biological Dosage form, preparation that provides active acquired immunity to a particular infectious disease, infectious or cancer, malignant disease. The safety and effectiveness of vaccines has been widely studied and verifi ...
developed by
Louis Pasteur Louis Pasteur (, ; 27 December 1822 – 28 September 1895) was a French chemist, pharmacist, and microbiologist renowned for his discoveries of the principles of vaccination, Fermentation, microbial fermentation, and pasteurization, the la ...
, Horsley corroborated his results and created a campaign to vaccinate against
rabies Rabies is a viral disease that causes encephalitis in humans and other mammals. It was historically referred to as hydrophobia ("fear of water") because its victims panic when offered liquids to drink. Early symptoms can include fever and abn ...
in the United Kingdom. As a pathologist, he carried out research on bacteria and founded the '' Journal of Pathology''. In June 1886, he was elected a
Fellow of the Royal Society Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is an award granted by the Fellows of the Royal Society of London to individuals who have made a "substantial contribution to the improvement of natural science, natural knowledge, incl ...
and, in 1891, jointly with his brother-in-law Francis Gotch, delivered their
Croonian Lecture The Croonian Medal and Lecture is a prestigious award, a medal, and lecture given at the invitation of the Royal Society and the Royal College of Physicians. Among the papers of William Croone at his death in 1684, was a plan to endow a singl ...
on the subject of the mammalian nervous system. In 1893, he was awarded the
Cameron Prize for Therapeutics of the University of Edinburgh The Cameron Prize for Therapeutics of the University of Edinburgh is awarded by the University of Edinburgh College of Medicine and Veterinary Medicine, College of Medicine and Veterinary Medicine to a person who has made any highly important and v ...
. A year later, in 1894, he won the
Royal Medal The Royal Medal, also known as The Queen's Medal and The King's Medal (depending on the gender of the monarch at the time of the award), is a silver-gilt medal, of which three are awarded each year by the Royal Society. Two are given for "the mo ...
for "his investigations relating to the physiology of the nervous system, and of the thyroid gland, and to their applications to the treatment of disease". Horsley, who had been a keen rifle shot when serving in the Artists' Rifles as a medical student, also investigated the effect of gunshot wounds on the brain, experimenting with animals provided by a butcher and using the recently issued Lee-Metford rifle. It dates the beginning of the experiments to 1894. He concluded that the immediate cause of death that follows was due to respiratory failure, not heart failure. It dates beginning of the experiments to 1893. His best-known innovation is the Horsley–Clarke apparatus, developed in 1908 together with Robert H. Clarke, for performing the so-called
stereotactic surgery Stereotactic surgery is a minimally invasive form of surgery, surgical intervention that makes use of a three-dimensional coordinates, coordinate system to locate small targets inside the body and to perform on them some action such as ablation, ...
, whereby a set of precise numerical coordinates are used to locate each brain structure. He was a pioneer in neurosurgery and operated on a total of 44 patients. He authored the book ''Functions of the Marginal Convolutions'' (1884) and, as a co-author, ''Experiments upon the Functions of the Cerebral Cortex'' (1888) and ''Alcohol and the Human Body'' (1902).


Political career

Horsley was a
Liberal Party The Liberal Party is any of many political parties around the world. The meaning of ''liberal'' varies around the world, ranging from liberal conservatism on the right to social liberalism on the left. For example, while the political systems ...
supporter and contested the December 1910 General election as a Liberal candidate for the
London University The University of London (UoL; abbreviated as Lond or more rarely Londin in post-nominals) is a federal public research university located in London, England, United Kingdom. The university was established by royal charter in 1836 as a degr ...
seat. The Animal Defence and Anti-Vivisection Society campaigned against his election because of his involvement with vivisection.The Newly Restored Bird Bath Memorial near the Thomas Carlyle Statue
Hilda Kean, hildakean.com
Following the election, he was adopted as prospective Liberal candidate, first for
Islington East Islington East was a United Kingdom constituencies, constituency which returned one Member of Parliament (United Kingdom), Member of Parliament (MP) to the House of Commons of the United Kingdom, House of Commons of the Parliament of the United ...
and then, in 1913, for Harborough in Leicestershire. Harborough was a Liberal seat and a general election, expected to take place in 1914 would most likely have seen him elected to parliament. However, he resigned as prospective candidate, citing opposition to his views on women's suffrage and temperance on the part of constituency officials, just before the
First World War World War I or the First World War (28 July 1914 – 11 November 1918), also known as the Great War, was a World war, global conflict between two coalitions: the Allies of World War I, Allies (or Entente) and the Central Powers. Fighting to ...
started. Horsley strongly supported the Liberals' welfare state initiative, the National Insurance Act of 1911, despite strong opposition from most of his medical colleagues.Michael S. Dunnill, "Victor Horsley (1857–1915) and National Insurance." ''
Journal of Medical Biography A journal, from the Old French ''journal'' (meaning "daily"), may refer to: *Bullet journal, a method of personal organization *Diary, a record of personal secretive thoughts and as open book to personal therapy or used to feel connected to onesel ...
'' 21.4 (2013): 249-254.


First World War service and death

In 1910, Horsley was commissioned as a
captain Captain is a title, an appellative for the commanding officer of a military unit; the supreme leader or highest rank officer of a navy ship, merchant ship, aeroplane, spacecraft, or other vessel; or the commander of a port, fire or police depa ...
in the Territorial Army, in the 3rd London General Hospital of the
Royal Army Medical Corps The Royal Army Medical Corps (RAMC) was a specialist corps in the British Army which provided medical services to all Army personnel and their families, in war and in peace. On 15 November 2024, the corps was amalgamated with the Royal Army De ...
. On the outbreak of the
First World War World War I or the First World War (28 July 1914 – 11 November 1918), also known as the Great War, was a World war, global conflict between two coalitions: the Allies of World War I, Allies (or Entente) and the Central Powers. Fighting to ...
, he volunteered for active duty on the Western Front, where he was initially posted as surgeon at the British hospital at Wimereux, France. In May 1915, he was posted as a
colonel Colonel ( ; abbreviated as Col., Col, or COL) is a senior military Officer (armed forces), officer rank used in many countries. It is also used in some police forces and paramilitary organizations. In the 17th, 18th, and 19th centuries, a colon ...
and Director of Surgery of the British Army Medical Service in Egypt, based at the 21st General Hospital in
Alexandria Alexandria ( ; ) is the List of cities and towns in Egypt#Largest cities, second largest city in Egypt and the List of coastal settlements of the Mediterranean Sea, largest city on the Mediterranean coast. It lies at the western edge of the Nile ...
, in support of the Dardanelles Campaign. In the following year, he volunteered for field surgery duty in
Mesopotamia Mesopotamia is a historical region of West Asia situated within the Tigris–Euphrates river system, in the northern part of the Fertile Crescent. Today, Mesopotamia is known as present-day Iraq and forms the eastern geographic boundary of ...
, where he died unexpectedly in
Amarah Amarah (), also spelled Amara, is a city in south-eastern Iraq, located on a low ridge next to the Tigris River waterway south of Baghdad about 50 km (31 mi) from the border with Iran. It lies at the northern tip of the marshlands between ...
, Iraq, on 16 July 1916, of heatstroke and severe
hyperpyrexia Fever or pyrexia in humans is a symptom of an anti-infection defense mechanism that appears with body temperature exceeding the normal range caused by an increase in the body's temperature set point in the hypothalamus. There is no single agre ...
, at only 59 years of age.


Namesakes

Horsley was the first neurosurgeon appointed to the hospital in
Queen Square, London Queen Square is a garden square in the Bloomsbury district of central London. Many of its buildings are associated with medicine, particularly neurology. Construction Queen Square was originally constructed between 1716 and 1725. It was forme ...
, now called the National Hospital for Neurology and Neurosurgery – the Victor Horsley Department of Neurosurgery is named in his honour. The Walton Centre for Neurology & Neurosurgery NHS Trust in Liverpool, England, another leading Neurosurgical Hospital, dedicated its intensive care unit to him, naming it the Horsley ward. At its Annual Representatives Meeting, the British Medical Association has a series of lunchtime lectures entitled The Victor Horsley Lectures. After the Second Gulf War, a British Field Hospital was established at Shaibah Logistics Base, and the area of tented accommodation for hospital staff was known as Horsley Lines. Horsley is credited with the invention of the "Horsley Hook", a device which he used to avulse the
trigeminal nerve In neuroanatomy, the trigeminal nerve (literal translation, lit. ''triplet'' nerve), also known as the fifth cranial nerve, cranial nerve V, or simply CN V, is a cranial nerve responsible for Sense, sensation in the face and motor functions ...
.


References


Further reading

* * * * *


External links


Horsley Papers
at
University College London University College London (Trade name, branded as UCL) is a Public university, public research university in London, England. It is a Member institutions of the University of London, member institution of the Federal university, federal Uni ...
{{DEFAULTSORT:Horsley, Victor Alexander Haden 1857 births 1916 deaths People from Kensington 19th-century English medical doctors Academics of University College London Alumni of University College London Anti-smoking activists English scientists English suffragists English neuroscientists Deaths from hyperthermia British endocrinologists Fellows of the Royal Society Fellows of the Royal College of Surgeons of England Food preservation Fullerian Professors of Physiology Knights Bachelor Male feminists English neurosurgeons Royal Army Medical Corps officers Royal Medal winners People educated at Cranbrook School, Kent Artists' Rifles soldiers British Army personnel of World War I British military personnel killed in World War I Burials at Amara War Cemetery Military personnel from the Royal Borough of Kensington and Chelsea Honorary medical staff at King Edward VII's Hospital for Officers