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A vial (also known as a phial or
flacon A ''flacon'' (from Late Latin , meaning "bottle"; cf. "flagon") is a small, often decorative, bottle. It has an opening seal or stopper and is designed to hold valuable liquids which may deteriorate upon contact with the air. They are widespread ...
) is a small glass or plastic vessel or bottle, often used to store
medication Medication (also called medicament, medicine, pharmaceutical drug, medicinal product, medicinal drug or simply drug) is a drug used to medical diagnosis, diagnose, cure, treat, or preventive medicine, prevent disease. Drug therapy (pharmaco ...
in the form of liquids, powders, or capsules. They can also be used as scientific sample vessels; for instance, in autosampler devices in analytical
chromatography In chemical analysis, chromatography is a laboratory technique for the Separation process, separation of a mixture into its components. The mixture is dissolved in a fluid solvent (gas or liquid) called the ''mobile phase'', which carries it ...
. Vial-like glass containers date back to
classical antiquity Classical antiquity, also known as the classical era, classical period, classical age, or simply antiquity, is the period of cultural History of Europe, European history between the 8th century BC and the 5th century AD comprising the inter ...
; modern vials are often made of plastics such as
polypropylene Polypropylene (PP), also known as polypropene, is a thermoplastic polymer used in a wide variety of applications. It is produced via chain-growth polymerization from the monomer Propene, propylene. Polypropylene belongs to the group of polyolefin ...
. There are different types of vials such as a single dose vial and multi-dose vials often used for medications. The single dose vial is only used once whereas a multi-dose vial can be used more than once. The CDC sets specific guidelines on multi-dose vials.


History and etymology

A vial can be tubular, or have a bottle-like shape with a neck. The volume defined by the neck is known as the headspace. The English word "vial" is derived from the
Greek Greek may refer to: Anything of, from, or related to Greece, a country in Southern Europe: *Greeks, an ethnic group *Greek language, a branch of the Indo-European language family **Proto-Greek language, the assumed last common ancestor of all kno ...
''phiale'', meaning "a broad flat container". Comparable terms include the
Latin Latin ( or ) is a classical language belonging to the Italic languages, Italic branch of the Indo-European languages. Latin was originally spoken by the Latins (Italic tribe), Latins in Latium (now known as Lazio), the lower Tiber area aroun ...
''phiala'',
Late Latin Late Latin is the scholarly name for the form of Literary Latin of late antiquity.Roberts (1996), p. 537. English dictionary definitions of Late Latin date this period from the 3rd to 6th centuries CE, and continuing into the 7th century in ...
''fiola'' and
Middle English Middle English (abbreviated to ME) is a form of the English language that was spoken after the Norman Conquest of 1066, until the late 15th century. The English language underwent distinct variations and developments following the Old English pe ...
''fiole'' and ''viole''.


Modern vials

Modern vials are often made out of glass or plastic. They are often used as storage for small quantities of liquid used in medical or molecular biology applications. There are several different types of commonly used closure systems. For glass vials, options include screw vials (closed with a screw cap or dropper/
pipette A pipette (sometimes spelled as pipet) is a type of laboratory tool commonly used in chemistry and biology to transport a measured volume of liquid, often as a media dispenser. Pipettes come in several designs for various purposes with differing ...
), lip vials (closed with a cork or plastic stopper) and crimp vials (closed with a rubber stopper and a metal cap). Plastic vials, which can be moulded in plastic, can have other closure systems, such as 'hinge caps' which snap shut when pressed. These are sometimes called flip-tops or snap caps. The bottom of a vial is often flat, unlike
test tube A test tube, also known as a culture tube or sample tube, is a common piece of laboratory glassware consisting of a finger-like length of glass or clear plastic tubing, open at the top and closed at the bottom. Test tubes are usually placed in s ...
s, which have usually a rounded bottom, but this is often not the case for small hinge-cap or snap-top vials. The small bottle-shaped vials typically used in laboratories are also known as bijou or McCartney's bottles. The bijou bottle tends to be smaller, often with a volume of around 10
milliliter The litre (Commonwealth English, Commonwealth spelling) or liter (American English, American spelling) (SI symbols L and l, other symbol used: ℓ) is a metric units, metric unit of volume. It is equal to 1 cubic decimetre (dm3), 1000 cubic c ...
s.


See also

*
Ampoule An ampoule (also ampul and ampule) is a small sealed vial which is used to contain and preserve a sample, usually a solid or liquid. Ampoules are usually made of glass. Modern ampoules are most commonly used to contain pharmaceuticals and chem ...
*
Seven bowls The seven bowls (, ''phialas'' (acc. pl.), nom. sing. φιάλη, ''phialē''; also translated as cups or vials) are a set of plagues mentioned in Revelation 16. They are recorded as apocalyptic events that were seen in the vision of the Reve ...
, also referred to as "seven vials", a series of plagues mentioned in the Biblical
Book of Revelation The Book of Revelation, also known as the Book of the Apocalypse or the Apocalypse of John, is the final book of the New Testament, and therefore the final book of the Bible#Christian Bible, Christian Bible. Written in Greek language, Greek, ...
*
Vacutainer A vacutainer blood collection tube is a sterile glass or plastic test tube with a colored rubber stopper creating a vacuum seal inside of the tube, facilitating the drawing of a predetermined volume of liquid. Vacutainer tubes may contain addit ...


References


Bibliography

* {{laboratory equipment Containers Dosage forms Laboratory glassware