Vectorial synthesis is synthesis of exported
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respon ...
s by
ribosomes in which the
ribosome-nascent chain complex
Ribosome-nascent chain complex (RNC) refers to the collection of molecules that constitute a ribosome attached to the polypeptide (protein) that it is synthesising. The synthesis of the nascent polypeptide may be stalled by one of several methods ...
is bound directly to the
endoplasmic reticulum
The endoplasmic reticulum (ER) is, in essence, the transportation system of the eukaryotic cell, and has many other important functions such as protein folding. It is a type of organelle made up of two subunits – rough endoplasmic reticulum ( ...
(ER) and the nascent peptide chain moves through the ER membrane as it emerges from the ribosome.
[
]
References
Further reading
Fuller-Pace, F., Peters, G., Dickson, C
''Cell transformation by kFGF requires secretion but not glycosylation'' Journal of Cell Biology (1991) 115 (2), pp. 547–555
Protein folding
Protein biosynthesis
{{Protein-stub