Vacuolar protein sorting-associated protein 11 homolog is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respon ...
that in humans is encoded by the ''VPS11''
gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...
.
Function
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway.
Interactions
VPS11 has been shown to
interact
Advocates for Informed Choice, dba interACT or interACT Advocates for Intersex Youth, is a 501(c)(3) nonprofit organization using innovative strategies to advocate for the legal and human rights of children with intersex traits. The organizat ...
with
VPS18
Vacuolar protein sorting-associated protein 18 homolog is a protein that in humans is encoded by the ''VPS18'' gene.
Function
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct orga ...
,
VPS33A
Vacuolar protein sorting-associated protein 33A is a protein that in humans is encoded by the ''VPS33A'' gene.
Function
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles ...
[ and ]STX7
Syntaxin-7 is a protein that in humans is encoded by the ''STX7'' gene.
In melanocytic cells STX7 gene expression may be regulated by MITF.
Interactions
STX7 has been shown to interact
Advocates for Informed Choice, dba interACT or int ...
.[
]
References
Further reading
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{{Gene-11-stub