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Una Ryan (born December 18, 1941) is a British-American biologist who has conducted research on vascular biology, publishing over 300 papers. After an extended research and academic career she began a career in the biotech industry. She was Director for Health Sciences of
Monsanto The Monsanto Company () was an American agrochemical and agricultural biotechnology corporation founded in 1901 and headquartered in Creve Coeur, Missouri. Monsanto's best-known product is Roundup, a glyphosate-based herbicide, developed ...
; CEO, president and director of AVANT Immunotherapeutics; and is currently the chairman of The Bay Area BioEconomy Initiative, among many other associations. She is an
angel investor An angel investor (also known as a business angel, informal investor, angel funder, private investor, or seed investor) is an individual who provides capital to a business or businesses, including startups, usually in exchange for convertible de ...
and focuses her funds on women-led companies. She has won numerous awards and recognition during her career including the
National Institutes of Health The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. It was founded in 1887 and is part of the United States Department of Health and Human Service ...
's 10-year merit award,
Order of the British Empire The Most Excellent Order of the British Empire is a British order of chivalry, rewarding valuable service in a wide range of useful activities. It comprises five classes of awards across both civil and military divisions, the most senior two o ...
and the
Albert Einstein Award The Albert Einstein Award was an award in theoretical physics, given periodically from 1951 to 1979, that was established to recognize high achievement in the natural sciences. It was endowed by the Lewis and Rosa Strauss Memorial Fund in honor ...
.


Biography

Una Scully was born on December 18, 1941 in
Kuala Lumpur Kuala Lumpur (KL), officially the Federal Territory of Kuala Lumpur, is the capital city and a Federal Territories of Malaysia, federal territory of Malaysia. It is the largest city in the country, covering an area of with a census population ...
,
Malaysia Malaysia is a country in Southeast Asia. Featuring the Tanjung Piai, southernmost point of continental Eurasia, it is a federation, federal constitutional monarchy consisting of States and federal territories of Malaysia, 13 states and thre ...
to a British father who was interned in a Japanese camp during
World War II World War II or the Second World War (1 September 1939 – 2 September 1945) was a World war, global conflict between two coalitions: the Allies of World War II, Allies and the Axis powers. World War II by country, Nearly all of the wo ...
. Scully and her mother fled by boat from Singapore to England, where she completed her education, graduating with a degree in
zoology Zoology ( , ) is the scientific study of animals. Its studies include the anatomy, structure, embryology, Biological classification, classification, Ethology, habits, and distribution of all animals, both living and extinction, extinct, and ...
from the
University of Bristol The University of Bristol is a public university, public research university in Bristol, England. It received its royal charter in 1909, although it can trace its roots to a Merchant Venturers' school founded in 1595 and University College, Br ...
in 1963. In 1965, she began publishing under the name of Una Smith and did so until 1973. She went on to complete a PhD at the
University of Cambridge The University of Cambridge is a Public university, public collegiate university, collegiate research university in Cambridge, England. Founded in 1209, the University of Cambridge is the List of oldest universities in continuous operation, wo ...
in 1967 and that same year moved to the United States, taking up a Howard Hughes Fellowship at the
University of Miami The University of Miami (UM, UMiami, Miami, U of M, and The U) is a private university, private research university in Coral Gables, Florida, United States. , the university enrolled 19,852 students in two colleges and ten schools across over ...
to study
angiotensin-converting enzyme Angiotensin-converting enzyme (), or ACE, is a central component of the renin–angiotensin system (RAS), which controls blood pressure by regulating the volume of fluids in the body. It converts the hormone angiotensin I to the active vasocon ...
s. After completion of the fellowship, Smith taught as a professor of life sciences and medicine at the
University of Miami School of Medicine The University of Miami Miller School of Medicine, officially Leonard M. Miller School of Medicine, is the University of Miami's graduate medical school in Miami, Florida. Founded in 1952, it is the oldest medical school in the state of Florida. ...
from 1972 to 1989. In 1975, her professional publishing reflected her name as U. S. Ryan or Una Scully Ryan. Her work at Miami was recognized by a 10-year Merit Award from the National Institutes of Health. In 1989, Ryan married the surgeon, Allan Dana Callow and then beginning in 1990, she worked as a Research Professor of Surgery, Medicine and Cell Biology at
Washington University School of Medicine Washington University School of Medicine (WashU Medicine) is the medical school of Washington University in St. Louis, located in the Central West End neighborhood of St. Louis, Missouri. Founded in 1891, the School of Medicine shares a ca ...
in
St. Louis, Missouri St. Louis ( , sometimes referred to as St. Louis City, Saint Louis or STL) is an Independent city (United States), independent city in the U.S. state of Missouri. It lies near the confluence of the Mississippi River, Mississippi and the Miss ...
. Simultaneously, she accepted a position at
Monsanto The Monsanto Company () was an American agrochemical and agricultural biotechnology corporation founded in 1901 and headquartered in Creve Coeur, Missouri. Monsanto's best-known product is Roundup, a glyphosate-based herbicide, developed ...
as Director for Health Sciences. She left Monsanto in 1992 and joined AVANT Immunotherapeutics Inc. as a vice-president and chief scientific researcher in May 1993. Around the same time, she left Washington University for a position as a Research Professor of Medicine at
Boston University School of Medicine The Boston University School of Medicine (formally the Chobanian and Avedisian School of Medicine) is the medical school of Boston University, a private university, private research university in Boston, Boston, Massachusetts. It was founded in ...
and obtained US citizenship in 1994. In 1996, Ryan was promoted to President at AVANT and also began serving as chief executive officer and President of Celldex Therapeutics Inc., all the while continuing to research and publish papers on vaccines against viral and bacterial diseases and for cholesterol management. Ryan was awarded the
Order of the British Empire The Most Excellent Order of the British Empire is a British order of chivalry, rewarding valuable service in a wide range of useful activities. It comprises five classes of awards across both civil and military divisions, the most senior two o ...
in 2002 for her contributions to research and development to biotechnology. In 2007, she was honored with the
Albert Einstein Award The Albert Einstein Award was an award in theoretical physics, given periodically from 1951 to 1979, that was established to recognize high achievement in the natural sciences. It was endowed by the Lewis and Rosa Strauss Memorial Fund in honor ...
for her development of new vaccines to combat global infectious diseases and then in 2008, she left the for-profit sector leaving her positions at AVANT and Celldex. In 2009 she was awarded an honorary doctorate from the University of Bristol. In addition to vaccines, Ryan has worked on clean water solutions and in 2009 was awarded a Cartier Women's Initiative Awards for a wastewater cleaning program using
blue-green algae Cyanobacteria ( ) are a group of autotrophic gram-negative bacteria that can obtain biological energy via oxygenic photosynthesis. The name "cyanobacteria" () refers to their bluish green (cyan) color, which forms the basis of cyanobacteria' ...
and
solar energy Solar energy is the radiant energy from the Sun's sunlight, light and heat, which can be harnessed using a range of technologies such as solar electricity, solar thermal energy (including solar water heating) and solar architecture. It is a ...
. Unable to secure venture capital funds for the program, Ryan turned her focus toward a program called Diagnostics for All, in an attempt to provide inexpensive diagnostic tests to developing countries. The innovation used paper tests and a drop of blood which when chemicals were applied would change color to indicate different results, without lab work required and simple disposal, as the paper could be burned. The company began with liver testing and then expanded their products to include pregnancy tests and a glucose monitoring test for diabetics. Deciding to relocate to the American west coast in 2013, Ryan accepted a position as the first woman to chair the Bay Area BioEconomy Initiative. While she was in Boston, Ryan had served on the board of the Biotechnology Industry Organization and the BioEconomy Initiative had similar aims of increasing efficiency and decreasing the time it takes for products to begin clinical trials and ultimately get to medical professionals. She also turned her focus to angel investing in an attempt to help women-run businesses find venture capital funds. Ryan served as managing director of Golden Seeds, as a partner in Astia Angel and participated with The Angel Forum all aimed at investing in startups and mentoring businesses in the Silicon Valley. She continues to serve on the boards of several biotechnology firms. In 2015, Ryan launched ULUX fine art based on her electron micrographs. Ryan has two daughters andfour grandchildren.


Selected works

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References


Bibliography

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External links


WorldCat Publications
{{DEFAULTSORT:Ryan, Una 1941 births 20th-century women scientists 21st-century American businesspeople 21st-century American businesswomen 21st-century American women scientists Albert Einstein World Award of Science Laureates Alumni of the University of Bristol Alumni of the University of Cambridge American investors American women investors Angel investors Biotechnologists Boston University faculty Living people Malaysian biologists Malaysian women scientists Officers of the Order of the British Empire People from Kuala Lumpur University of Miami faculty Washington University School of Medicine faculty Women biotechnologists