The Upstream pseudoknot (UPSK) domain is an
RNA element found in the
turnip yellow mosaic virus,
beet virus Q,
barley stripe mosaic virus
Barley stripe mosaic virus (BSMV), of genus ''Hordevirus'', is an RNA viral plant pathogen whose main hosts are barley and wheat. The common symptoms for BSMV are yellow streaks or spots, mosaic, leaves and stunted growth. It is spread primaril ...
and
tobacco mosaic virus
Tobacco mosaic virus (TMV) is a positive-sense single-stranded RNA virus species in the genus '' Tobamovirus'' that infects a wide range of plants, especially tobacco and other members of the family Solanaceae. The infection causes characteris ...
,
which is thought to be needed for efficient
transcription. Disruption of the
pseudoknot
__NOTOC__
A pseudoknot is a nucleic acid secondary structure containing at least two stem-loop structures in which half of one stem is intercalated between the two halves of another stem. The pseudoknot was first recognized in the turnip yellow ...
structure gives rise to a 50% drop in transcription efficiency. This element acts in conjunction with the
Tymovirus/Pomovirus tRNA-like 3' UTR element to enhance translation.
References
External links
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Cis-regulatory RNA elements
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