UCSF648 is an experimental drug which acts as a selective

partial agonist In pharmacology, partial agonists are drugs that bind to and activate a given Receptor (biochemistry), receptor, but have only partial Intrinsic activity, efficacy at the receptor relative to a full agonist. They may also be considered Ligand (bio ...

for the 5-HT_5A

serotonin receptor 5-HT receptors, 5-hydroxytryptamine receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in multiple tissues including the central and peripheral nervous systems. They mediate both ex ...

. Very few selective ligands are available for this receptor, and UCSF648 is expected to be useful in researching its structure and function.

References

5-HT5A agonists Experimental drugs Quinolines Sulfones Chloroarenes Secondary amines {{nervous-system-drug-stub