UCSC Malaria Genome Browser is a bioinformatic research tool to study the

malaria Malaria is a Mosquito-borne disease, mosquito-borne infectious disease that affects vertebrates and ''Anopheles'' mosquitoes. Human malaria causes Signs and symptoms, symptoms that typically include fever, Fatigue (medical), fatigue, vomitin ...

genome, developed by Hughes Undergraduate Research Laboratory together with the laboratory of Prof. Manuel Ares Jr. at the

University of California, Santa Cruz The University of California, Santa Cruz (UC Santa Cruz or UCSC) is a public university, public Land-grant university, land-grant research university in Santa Cruz, California, United States. It is one of the ten campuses in the University of C ...

. The web interface and database structure is based on the UCSC

Genome Browser The completion of the human genome sequencing in the early 2000s was a turning point in genomics research. Scientists have conducted series of research into the activities of genes and the genome as a whole. The human genome contains around 3 billio ...

. UCSC Malaria Genome Browser brings together on a single screen the full

DNA sequence A nucleic acid sequence is a succession of bases within the nucleotides forming alleles within a DNA (using GACT) or RNA (GACU) molecule. This succession is denoted by a series of a set of five different letters that indicate the order of the nu ...

s of several species of the malaria parasite (''Plasmodium sp.''), alongside experimental results and previously discovered genes collected from the literature. The program allows users to search through 14 chromosomes of the malaria parasite's genome, enter their own sequence data and notes, and compare findings across species. The Malaria Genome Browser also supports text and sequence based searches that provide quick, precise access to any region of specific interest in the malaria genome. This site contains the

reference genome A reference genome (also known as a reference assembly) is a digital nucleic acid sequence database, assembled by scientists as a representative example of the genome, set of genes in one idealized individual organism of a species. As they are a ...

sequence and working draft assembly for ''Plasmodium falciparum'' from PlasmoDb, the ''Plasmodium'' genome database build 5.0.

References

External links

UCSC Malaria Genome Browser

UCSC Genome Browser for human, vertebrate, invertebrate and other species

Ares lab page

UCSC Genome Browser tutorials
Genome databases Malaria {{genetics-stub