Ubiquilin 4 is a

protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respon ...

in humans that is encoded by the UBQLN4

gene In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...

. Ubiquilin 4 regulates proteasomal protein degradation.

Similarity to Other Proteins

Human UBQLN4 shares a high degree of similarity with related ubiquilins including

UBQLN1 Ubiquilin-1 is a protein that in humans is encoded by the ''UBQLN1'' gene. Ubiquilins contain two domains, an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubi ...

and UBQLN2.

References

External links

* {{gene-1-stub