Type V collagen is a form of fibrillar
collagen associated with classical
Ehlers-Danlos syndrome. It is found within the
dermal/epidermal junction
The dermoepidermal junction or dermal-epidermal junction (DEJ) is the area of tissue that joins the epidermal and the dermal layers of the skin. The basal cells in the stratum basale of the epidermis connect to the basement membrane by the anchori ...
, placental tissues, as well as in association with tissues containing
type I collagen
Type I collagen is the most abundant collagen of the human body. It forms large, eosinophilic fibers known as collagen fibers.
It is present in scar tissue, the end product when tissue heals by repair, as well as tendons, ligaments, the endom ...
.
Autoimmunity against type V collagen is associated with lung transplant failure.
Genes
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COL5A1
Collagen alpha-1(V) chain is a protein that in humans is encoded by the ''COL5A1'' gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' ...
,
COL5A2
Collagen alpha-2(V) chain is a protein that in humans is encoded by the ''COL5A2'' gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' o ...
,
COL5A3
Collagen alpha-3(V) chain is a protein that in humans is encoded by the ''COL5A3'' gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' ...
References
External links
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Collagens
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